Melanopsin Forms a Functional Short-Wavelength Photopigment

Biochemistry

Volumn 42, Issue 44, 2003, Pages 12734-12738

  Newman, Lucy A ^a   Walker, Marquis T ^a   Brown, R Lane ^b   Cronin, Thomas W ^a   Robinson, Phyllis R ^a  

^a UNIVERSITY OF MARYLAND BALTIMORE COUNTY   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; CHROMOPHORES; NEUROLOGY; PROTEINS; SPECTRUM ANALYSIS; VISION;

LIGHT-DARK CYCLES;

PIGMENTS;

11 CIS RETINAL; GUANINE NUCLEOTIDE BINDING PROTEIN; MELANOPSIN; OPSIN; SHORT WAVELENGTH PHOTOPIGMENT; TRANSDUCIN; UNCLASSIFIED DRUG;

ABSORPTION SPECTROSCOPY; ARTICLE; BEHAVIOR; CELL STRAIN COS1; CIRCADIAN PACEMAKER; CIRCADIAN RHYTHM; CORTICAL SYNCHRONIZATION; HYPOTHALAMUS; LIGHT DARK CYCLE; NERVE PROJECTION; NERVE TRACT; PACEMAKER; PHOTORECEPTOR; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; RETINA; RETINA CONE; RETINA GANGLION CELL; RETINA ROD; RETINOHYPOTHALAMIC TRACT; SIGNAL TRANSDUCTION; SPECTROSCOPY; SUPRACHIASMATIC NUCLEUS;

AMINO ACID SEQUENCE; ANIMALS; CATTLE; CERCOPITHECUS AETHIOPS; CIS-TRANS-ISOMERASES; COS CELLS; LIGHT; MICE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; OPSIN; PHOTOPERIOD; RETINAL GANGLION CELLS; SIGNAL TRANSDUCTION; SPECTROPHOTOMETRY; TRANSDUCIN; TRANSFECTION;

MAMMALIA;

EID: 0242507495     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi035418z     Document Type: Article

References (26)

1. Moore, R. Y., Speh, J. C., and Card, J. P. (1995) The retinohypothalamic tract originates from a distinct subset of retinal ganglion cells, J. Comput. Neurol. 352, 351-366.
2. Freedman, M. S., Lucas, R. J., Soni, B., von Schantz, M., Munoz, M., David-Gray, Z., and Foster, R. (1999) Regulation of mammalian circadian behavior by non-rod, non-cone, ocular photoreceptors, Science 284, 502-504.
3. Berson, D. M., Dunn, F. A., and Takao, M. (2002) Phototransduction by retinal ganglion cells that set the circadian clock, Science 295, 1070-1073.
4. Lucas, R. J., Douglas, R. H., and Foster, R. G. (2001) Characterization of an ocular photopigment capable of driving pupillary constriction in mice, Nat. Neurosci. 4, 621-626.
5. Foster, R. G. (2002) Keeping an eye on the time: the Cogan Lecture, Invest. Ophthalmol. Visual Sci., 1286-1298.
6. Provencio, I., Rodriguez, I. R., Jiang, G., Hayes, W. P., Moreira, E. F., and Rollag, M. D. (2000) A novel human opsin in the inner retina, J. Neurosci. 20, 600-605.
7. Gooley, J. J., Lu, J., Chou, T. C., Scammell, T. E., and Saper, C. B. (2001) Melanopsin in cells of origin of the retinohypothalamic tract, Nat. Neurosci. 4, 1165.
8. Hannibal, J., Hindersson, P., Knudsen, S. M., Georg, B., and Fahrenkrug, J. (2002) The photopigment melanopsin is exclusively present in pituitary adenylate cyclase-activating polypeptide-containing retinal ganglion cells of the retinohypothalamic tract, J. Neurosci. 22, 1-7.
9. Hattar, S., Liao, H. W., Takao, M., Berson, D. M., and Yau, K.-W. (2002) Melanopsin-containing retinal ganglion cells: architecture, projections, and intrinsic photosensitivity, Science 295, 1065-1070.
10. Panda, S., Sato, T. K., Castrucci, A. M., Rollag, M. D., DeGrip, W. J., Hogenesch, J. B., Provencio, I., and Kay, S. A. (2002) Melanopsin (Opn4) requirement for normal light-induced circadian phase shifting, Science 298, 2213-2216.
11. Ruby, N. F., Brennan, T. J., Xie, X., Cao, V., Franken, P., Heller, H. C., and O'Hara, B. F. (2002) Role of melanopsin in circadian responses to light, Science 298, 2211-2213.
12. Lucas, R. J., Hattar, S., Takao, M., Berson, D. M., Foster, R. G., and Yau, K.-W. (2003) Diminished pupillary light reflex at high irradiances in melanopsin-knockout mice, Science 29, 245-247.
13. Menaker, M. (2003) Circadian photoreception, Science 299, 213-214.
14. Hattar, S., Lucas, R. J., Mrosovsky, N., Thompson, S., Douglas, R. H., Hankins, M. W., Lem, J., Biel, M., Hofman, F., Foster, R. G., and Yau, K.-W. (2003) Melanopsin and rod-cone photoreceptive systems account for all major accessory visual functions in mice, Nature 424, 75-81.
15. Hao, W., and Fong, H. K. (1996) Blue and ultraviolet light-absorbing opsin from the retinal pigment epithelium, Biochemistry 35, 6251-256.
16. Molday, R. S., and Mac Kenzie, D. (1983) Monoclonal antibodies to rhodopsin: Characterization, cross reactivity, and application as structural probes, Biochemistry 22, 653-660.
17. o in an in vitro reconstitution system, J. Biol. Chem. 272, 33100-33104.
18. Kaufman, R. J., Davies, M. V., Pathak, V. K., and Hershey, J. W. B. (1989) The phosphorylation state of eucaryotic initiation factor 2 alters translational efficiency of specific mRNAs, Mol. Cell. Biol. 9, 946-958.
19. Oprian, D. D. (1993) in Methods in Neurosciences: Photoreceptor Cells (Hargrave, P. A., Ed.) pp 301-306, Academic Press, San Diego.
20. Zhukovsky, E. A., Robinson, P. R., and Oprian, D. D. (1991) Transducin activation by rhodopsin without a covalent bond to 11-cis-retinal chromophore, Science 251, 558-560.
21. Laemmli, U. K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4, Nature 227, 680-685.
22. Bloom, H., Beir, H., and Gross, H. S. (1987) Electrophoresis 8, 93-99.
23. Burnett, W. N. (1981) Western blotting: electrophoretic transfer of proteins from sodium dodecyl sulfate-polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A, Anal. Biochem. 112, 195-203.
24. Menon, S. T., Han, M., and Sakmar, T. P. (2001) Rhodopsin: structural basis of molecular physiology, Physiol Rev. 81, 1659-1688.
25. Fasick, J. I., Cronin, T. W., Hunt, D. M., and Robinson, P. R. (1998) The visual pigments of the bottlenose dolphin (Tursiops truncatus), Visual Neurosci. 15, 643-651.
26. Wang, Z., Asenjo, A. B., and Oprian, D. D. (1993) Identification of the Cl binding site in the human and green color vision pigments, Biochemistry 32, 2125-2130.