HER2-positive advanced breast cancer: Optimizing patient outcomes and opportunities for drug development

British Journal of Cancer

Volumn 111, Issue 10, 2014, Pages 1888-1898

  Singh, J C ^a   Jhaveri, K ^a   Esteva, F J ^a  

^a NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

breast neoplasm; Erbb 2; lapatinib; pertuzumab; trastuzumab; trastuzumab DM1

Indexed keywords

ANTINEOPLASTIC AGENT; EPIDERMAL GROWTH FACTOR RECEPTOR 2; HEAT SHOCK PROTEIN 90 INHIBITOR; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN KINASE B INHIBITOR; PROTEIN TYROSINE KINASE INHIBITOR; TRASTUZUMAB; ERBB2 PROTEIN, HUMAN;

BRAIN METASTASIS; BREAST CANCER; BREAST METASTASIS; CANCER CHEMOTHERAPY; CANCER GROWTH; CANCER RESISTANCE; DRUG DEVELOPMENT; DRUG EFFICACY; DRUG TARGETING; EPIDERMAL GROWTH FACTOR RECEPTOR 2 POSITIVE BREAST CANCER; HIGH THROUGHPUT SEQUENCING; HUMAN; MOLECULARLY TARGETED THERAPY; MULTICENTER STUDY (TOPIC); NONHUMAN; PHASE 1 CLINICAL TRIAL (TOPIC); PHASE 2 CLINICAL TRIAL (TOPIC); PHASE 3 CLINICAL TRIAL (TOPIC); PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; TREATMENT OUTCOME; TREATMENT RESPONSE; ANTAGONISTS AND INHIBITORS; BREAST NEOPLASMS; DRUG DESIGN; FEMALE; METABOLISM;

ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; DRUG DESIGN; FEMALE; HUMANS; MOLECULAR TARGETED THERAPY; RECEPTOR, ERBB-2;

EID: 84917698578     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/bjc.2014.388     Document Type: Review

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