CCR1-mediated accumulation of myeloid cells in the liver microenvironment promoting mouse colon cancer metastasis

Clinical and Experimental Metastasis

Volumn 31, Issue 8, 2014, Pages 977-989

  Hirai, Hideyo ^a   Fujishita, Teruaki ^a,e   Kurimoto, Kazuki ^a   Miyachi, Hitoshi ^a   Kitano, Satsuki ^a   Inamoto, Susumu ^a   Itatani, Yoshiro ^a,f   Saitou, Mitinori ^a,b,c,d   Maekawa, Taira ^a   Taketo, M Mark ^a  

^a KYOTO UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c KYOTO UNIVERSITY   (Japan)

^d KYOTO UNIVERSITY   (Japan)

^e AICHI CANCER CENTER HOSPITAL   (Japan)

^f UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

CCR1; Colon cancer; Fibrocytes; Liver metastasis; MMP2; MMP9; Neutrophils

Indexed keywords

CHEMOKINE RECEPTOR CCR1; FLUORESCENT DYE; GELATINASE A; GELATINASE B; CCR1 PROTEIN, MOUSE; MESSENGER RNA; MMP2 PROTEIN, MOUSE; MMP9 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL ARTIFICIAL CHROMOSOME; BONE MARROW CELL; COLORECTAL LIVER METASTASIS; CONTROLLED STUDY; CYTOLOGY; EOSINOPHIL; FLOW CYTOMETRY; GENE EXPRESSION; GENE INACTIVATION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; METASTATIC COLORECTAL CANCER; MONOCYTE; MOUSE; MOUSE MODEL; NEUTROPHIL; NONHUMAN; PROMOTER REGION; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA HYBRIDIZATION; SPLEEN; TRANSGENIC MOUSE; TUMOR MICROENVIRONMENT; ANIMAL; C57BL MOUSE; CELL CYCLE; CELL MOTION; COLON TUMOR; DISEASE MODEL; ENZYME IMMUNOASSAY; GENETICS; IN SITU HYBRIDIZATION; KNOCKOUT MOUSE; LIVER TUMOR; METABOLISM; PATHOLOGY; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; SECONDARY; TUMOR CELL CULTURE; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; BONE MARROW CELLS; CELL CYCLE; CELL MOVEMENT; COLONIC NEOPLASMS; DISEASE MODELS, ANIMAL; FLOW CYTOMETRY; HUMANS; IMMUNOENZYME TECHNIQUES; IN SITU HYBRIDIZATION; LIVER NEOPLASMS; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; MYELOID CELLS; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, CCR1; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TUMOR CELLS, CULTURED; TUMOR MICROENVIRONMENT;

EID: 84917676700     PISSN: 02620898     EISSN: 15737276     Source Type: Journal    
DOI: 10.1007/s10585-014-9684-z     Document Type: Article

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