Effects of BRAF mutations and BRAF inhibition on immune responses to melanoma

Molecular Cancer Therapeutics

Volumn 13, Issue 12, 2014, Pages 2769-2783

  Ilieva, Kristina M ^a   Correa, Isabel ^a   Josephs, Debra H ^a,b   Karagiannis, Panagiotis ^a   Egbuniwe, Isioma U ^a   Cafferkey, Michiala J ^a   Spicer, James F ^b   Harries, Mark ^b   Nestle, Frank O ^a   Lacy, Katie E ^a   Karagiannis, Sophia N ^a  

^a ST THOMAS HOSPITAL   (United Kingdom)

^b GUY S HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

3 (2,6 DICHLORO 3,5 DIMETHOXYPHENYL) 1 [6 [[4 (4 ETHYL 1 PIPERAZINYL)PHENYL]AMINO] 4 PYRIMIDINYL] 1 METHYLUREA; 4 DIALLYLAMINOMETHYLENE 1,3,4,7,10,11,12,13,14,15,16,17 DODECAHYDRO 6 HYDROXY 1 METHOXYMETHYL 10,13 DIMETHYL 3,7,17 TRIOXO 2 OXACYCLOPENTA[A]PHENANTHREN 11 YL ACETATE; ALPHA2B INTERFERON; B RAF KINASE; B RAF KINASE INHIBITOR; BINIMETINIB; BUPARLISIB; CAPMATINIB; CHIR 265; COBIMETINIB; CYCLOPHOSPHAMIDE; DABRAFENIB; DACARBAZINE; ENCORAFENIB; FAMOTIDINE; FLUDARABINE; IPILIMUMAB; PLACEBO; RECOMBINANT INTERLEUKIN 12; RECOMBINANT INTERLEUKIN 2; RIBOCICLIB; SORAFENIB; TRAMETINIB; VEMURAFENIB; XL 281; PROTEIN KINASE INHIBITOR;

ADOPTIVE IMMUNOTHERAPY; CANCER CHEMOTHERAPY; CANCER COMBINATION CHEMOTHERAPY; CANCER IMMUNOTHERAPY; CANCER PATIENT; CLINICAL EVALUATION; CLINICAL TRIAL (TOPIC); CUTANEOUS MELANOMA; CYTOTOXICITY; DRUG EFFICACY; DRUG SAFETY; GENE MUTATION; HUMAN; IMMUNE RESPONSE; IMMUNOGENICITY; IMMUNOSUPPRESSIVE TREATMENT; MELANOMA; MELANOMA CELL; METASTATIC MELANOMA; MONOTHERAPY; MUTANT; NEOPLASM; PROGRESSION FREE SURVIVAL; REVIEW; TUMOR IMMUNITY; ANIMAL; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; ENZYME ACTIVATION; GENETICS; IMMUNOLOGY; METABOLISM; MOLECULARLY TARGETED THERAPY; MULTIMODALITY CANCER THERAPY; MUTATION; SIGNAL TRANSDUCTION; TRANSLATIONAL RESEARCH; TUMOR ESCAPE;

ANIMALS; COMBINED MODALITY THERAPY; ENZYME ACTIVATION; HUMANS; MELANOMA; MOLECULAR TARGETED THERAPY; MUTATION; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS B-RAF; SIGNAL TRANSDUCTION; TRANSLATIONAL MEDICAL RESEARCH; TUMOR ESCAPE;

EID: 84917673811     PISSN: 15357163     EISSN: 15388514     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-14-0290     Document Type: Review

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