11′-Deoxyverticillin A (C42) promotes autophagy through K-Ras/GSK3 signaling pathway in HCT116 cells

Protein and Cell

Volumn 5, Issue 12, 2014, Pages 945-949

  Niu, Shubin ^a,b,c   Yuan, Dongdong ^a,d   Jiang, Xuejun ^a   Che, Yongsheng ^b  

^a INSTITUTE OF MICROBIOLOGY   (China)

^b BEIJING INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY   (China)

^c UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^d Shandong Academy of Pharmaceutical Science   (China)

Author keywords

[No Author keywords available]

Indexed keywords

11 DEOXYVERTICILLIN A; ACTIN; BAFILOMYCIN A1; GLYCOGEN SYNTHASE KINASE 3; GREEN FLUORESCENT PROTEIN; K RAS PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; MYCOTOXIN; NATURAL PRODUCT; UNCLASSIFIED DRUG; 11,11'-DIDEOXYVERTICILLIN A; ANTINEOPLASTIC AGENT; DISULFIDE; KRAS PROTEIN, HUMAN; ONCOPROTEIN; PIPERAZINE DERIVATIVE; RAS PROTEIN;

ANTINEOPLASTIC ACTIVITY; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ELECTRON MICROSCOPY; GENE EXPRESSION; GENE SILENCING; GENETIC TRANSFECTION; GSK3 SIGNALING PATHWAY; HCT116 CELL LINE; HUMAN; HUMAN CELL; K RAS SIGNALING PATHWAY; NEOPLASM; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM;

ANTINEOPLASTIC AGENTS; AUTOPHAGY; DISULFIDES; GENE EXPRESSION REGULATION, NEOPLASTIC; GLYCOGEN SYNTHASE KINASE 3; HCT116 CELLS; HUMANS; PIPERAZINES; PROTO-ONCOGENE PROTEINS; RAS PROTEINS; SIGNAL TRANSDUCTION;

EID: 84916940369     PISSN: 1674800X     EISSN: 16748018     Source Type: Journal    
DOI: 10.1007/s13238-014-0099-z     Document Type: Article

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