Lack of GABAB receptors modifies behavioural and biochemical alterations induced by precipitated nicotine withdrawal

Neuropharmacology

Volumn 90, Issue , 2015, Pages 90-101

  Varani, Andrés P ^a   Pedrón, Valeria T ^a   Machado, Lirane Moutinho ^a   Antonelli, Marta C ^b   Bettler, Bernhard ^c   Balerio, Graciela N ^a,d  

^a Instituto de Investigaciones Farmacologicas   (Argentina)

^b Instituto de Quimica y Fisicoquimica Biologicas Buenos Aires   (Argentina)

^c UNIVERSITY OF BASEL   (Switzerland)

^d UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

Anxiety; BDNF; Corticosterone; Epibatidine; GABAB receptor; Mice; Monoamines; Nicotine; Withdrawal

Indexed keywords

3,4 DIHYDROXYPHENYLACETIC ACID; 4 AMINOBUTYRIC ACID B RECEPTOR; BRAIN DERIVED NEUROTROPHIC FACTOR; CORTICOSTERONE; DOPAMINE; MECAMYLAMINE; MONOAMINE; TRITIUM; 4 AMINOBUTYRIC ACID A RECEPTOR; GABRB1 PROTEIN, MOUSE; NICOTINE; NICOTINIC AGENT; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR BLOCKING AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANXIETY; ARTICLE; BINDING SITE; BRAIN CORTEX; BRAIN LEVEL; CONTROLLED STUDY; ELEVATED PLUS MAZE TEST; HIPPOCAMPUS; MALE; MOUSE; NONHUMAN; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; SMOKING CESSATION; TOBACCO DEPENDENCE; ANIMAL; BAGG ALBINO MOUSE; BLOOD; BRAIN; DEFICIENCY; DISEASE MODEL; DRUG EFFECTS; GENETICS; KNOCKOUT MOUSE; METABOLISM; PATHOPHYSIOLOGY; TOBACCO USE DISORDER; WITHDRAWAL SYNDROME;

ANIMALS; ANXIETY; BRAIN; BRAIN-DERIVED NEUROTROPHIC FACTOR; CORTICOSTERONE; DISEASE MODELS, ANIMAL; MALE; MECAMYLAMINE; MICE, INBRED BALB C; MICE, KNOCKOUT; NICOTINE; NICOTINIC AGONISTS; NICOTINIC ANTAGONISTS; RECEPTORS, GABA-A; RECEPTORS, NICOTINIC; SUBSTANCE WITHDRAWAL SYNDROME; TOBACCO USE DISORDER;

EID: 84916918781     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2014.11.013     Document Type: Article

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