Tissue phosphoproteomics with PolyMAC identifies potential therapeutic targets in a transgenic mouse model of HER2 positive breast cancer

Electrophoresis

Volumn 35, Issue 24, 2014, Pages 3463-3469

  Searleman, Adam C ^a   Iliuk, Anton B ^b   Collier, Timothy S ^a,d   Chodosh, Lewis A ^c   Tao, W Andy ^b   Bose, Ron ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Purdue University   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d Cleveland Heart Lab   (United States)

Author keywords

Breast Cancer; Drug identification; HER2; Phosphoproteomics; PolyMAC

Indexed keywords

AMINO ACIDS; DISEASES; GENE THERAPY; LIQUID CHROMATOGRAPHY; MAMMALS; METAL IONS; PHOSPHORYLATION; TISSUE;

BREAST CANCER; DRUG IDENTIFICATION; HER2; METAL ION AFFINITIES; PHOSPHOPROTEOMES; PHOSPHOPROTEOMICS; PHOSPHOTYROSINE; POLYMER BASED; POLYMER-BASED METAL ION AFFINITY CAPTURE; THERAPEUTIC TARGETS;

PEPTIDES;

EPIDERMAL GROWTH FACTOR RECEPTOR 2; PHOSPHOSERINE; PHOSPHOTHREONINE; PHOSPHOTYROSINE; POLYMER; PROTEIN TYROSINE KINASE; ERBB2 PROTEIN, MOUSE; PHOSPHOAMINO ACID; PHOSPHOPEPTIDE;

ANALYTIC METHOD; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST CANCER; CONTROLLED STUDY; FEMALE; HER2 POSITIVE BREAST CANCER; HISTOPATHOLOGY; IMMUNOPRECIPITATION; INTERMETHOD COMPARISON; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MOUSE; NONHUMAN; POLYMER BASED METAL ION AFFINITY CAPTURE; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; PROTEOMICS; REVERSED PHASE LIQUID CHROMATOGRAPHY; TISSUE CHARACTERIZATION; TRANSGENIC MOUSE; WESTERN BLOTTING; AFFINITY CHROMATOGRAPHY; ANIMAL; BIOSYNTHESIS; CHEMISTRY; ENZYMOLOGY; EXPERIMENTAL MAMMARY NEOPLASM; MALE; METABOLISM; PROCEDURES; TANDEM MASS SPECTROMETRY; TISSUE MICROARRAY;

ANIMALS; CHROMATOGRAPHY, AFFINITY; FEMALE; MALE; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE; MICE, TRANSGENIC; PHOSPHOAMINO ACIDS; PHOSPHOPEPTIDES; PROTEOMICS; RECEPTOR, ERBB-2; TANDEM MASS SPECTROMETRY; TISSUE ARRAY ANALYSIS;

EID: 84916884725     PISSN: 01730835     EISSN: 15222683     Source Type: Journal    
DOI: 10.1002/elps.201400022     Document Type: Article

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