GYY4137, a hydrogen sulfide-releasing molecule, inhibits the inflammatory response by suppressing the activation of nuclear factor-kappa B and mitogen-activated protein kinases in Coxsackie virus B3-infected rat cardiomyocytes

Molecular Medicine Reports

Volumn 11, Issue 3, 2015, Pages 1837-1844

  Wu, Zubo ^a   Peng, Hua ^a   Du, Qing ^a   Lin, Wen ^a   Liu, Yali ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Cardiomyocytes; Coxsackie virus B3; GYY4137; Mitogen activated protein kinase; Nuclear factor B

Indexed keywords

ANTIINFLAMMATORY AGENT; CREATINE KINASE MB; GYY 4137; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; LACTATE DEHYDROGENASE; MITOGEN ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; AUTACOID; DNA BINDING PROTEIN; HYDROGEN SULFIDE; MORPHOLINE DERIVATIVE; PHOSPHOROTHIOIC ACID DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; COXSACKIE VIRUS B3; COXSACKIE VIRUS INFECTION; CYTOKINE PRODUCTION; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; GEL MOBILITY SHIFT ASSAY; HEART FAILURE; IMMUNOCOMPETENT CELL; IMMUNOFLUORESCENCE; INFLAMMATION; MOUSE; NONHUMAN; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; VIRUS MYOCARDITIS; WESTERN BLOTTING; ACTIVE TRANSPORT; ANIMAL; CELL CULTURE; COMPLICATION; DRUG EFFECTS; ENTEROVIRUS B; ENZYME ACTIVATION; HEART MUSCLE CELL; HUMAN; METABOLISM; MYOCARDITIS; PHYSIOLOGY; PROTEIN TRANSPORT; RAT; VIROLOGY;

COXSACKIEVIRUS; RATTUS;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; ANTI-INFLAMMATORY AGENTS; CELLS, CULTURED; COXSACKIEVIRUS INFECTIONS; DNA-BINDING PROTEINS; ENTEROVIRUS B, HUMAN; ENZYME ACTIVATION; HUMANS; HYDROGEN SULFIDE; INFLAMMATION MEDIATORS; MITOGEN-ACTIVATED PROTEIN KINASES; MORPHOLINES; MYOCARDITIS; MYOCYTES, CARDIAC; NF-KAPPA B; ORGANOTHIOPHOSPHORUS COMPOUNDS; PROTEIN TRANSPORT; PROTEOLYSIS; RATS;

EID: 84916608313     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2014.2901     Document Type: Article

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