메뉴 건너뛰기




Volumn 28, Issue 1, 2015, Pages 42-51

Renal function three years after early conversion from a calcineurin inhibitor to everolimus: Results from a randomized trial in kidney transplantation

Author keywords

calcineurin inhibitor; conversion; everolimus; glomerular filtration rate; kidney transplantation; long term; renal function

Indexed keywords

CHOLESTEROL; CORTICOSTEROID; CYCLOSPORIN; EVEROLIMUS; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MYCOPHENOLIC ACID; TRIACYLGLYCEROL; CALCINEURIN INHIBITOR; IMMUNOSUPPRESSIVE AGENT; RAPAMYCIN;

EID: 84916594803     PISSN: 09340874     EISSN: 14322277     Source Type: Journal    
DOI: 10.1111/tri.12437     Document Type: Article
Times cited : (39)

References (34)
  • 1
    • 79953250784 scopus 로고    scopus 로고
    • Chronic calcineurin inhibitor nephrotoxicity - Lest we forget
    • Chapman JR,. Chronic calcineurin inhibitor nephrotoxicity-lest we forget. Am J Transplant 2011; 11: 693.
    • (2011) Am J Transplant , vol.11 , pp. 693
    • Chapman, J.R.1
  • 2
    • 79961032806 scopus 로고    scopus 로고
    • The ORION study: Comparison of two sirolimus-based regimens versus tacrolimus and mycophenolate mofetil in renal allograft recipients
    • Flechner SM, Glyda M, Cockfield S, et al,. The ORION study: comparison of two sirolimus-based regimens versus tacrolimus and mycophenolate mofetil in renal allograft recipients. Am J Transplant 2011; 11: 1633.
    • (2011) Am J Transplant , vol.11 , pp. 1633
    • Flechner, S.M.1    Glyda, M.2    Cockfield, S.3
  • 3
    • 37349034394 scopus 로고    scopus 로고
    • Reduced exposure to calcineurin inhibitors in renal transplantation
    • Ekberg H, Tedesco-Silva H, Demirbas A, et al,. Reduced exposure to calcineurin inhibitors in renal transplantation. N Engl J Med 2007; 357: 2562.
    • (2007) N Engl J Med , vol.357 , pp. 2562
    • Ekberg, H.1    Tedesco-Silva, H.2    Demirbas, A.3
  • 4
    • 33847717932 scopus 로고    scopus 로고
    • Mycophenolate mofetil/sirolimus compared to other common immunosuppressive regimens in kidney transplantation
    • Srinivas TR, Schold JD, Guerra G, Eagan A, Bucci CM, Meier-Kriesche HU,. Mycophenolate mofetil/sirolimus compared to other common immunosuppressive regimens in kidney transplantation. Am J Transplant 2007; 7: 586.
    • (2007) Am J Transplant , vol.7 , pp. 586
    • Srinivas, T.R.1    Schold, J.D.2    Guerra, G.3    Eagan, A.4    Bucci, C.M.5    Meier-Kriesche, H.U.6
  • 5
    • 0035872742 scopus 로고    scopus 로고
    • Multicenter trial exploring calcineurin inhibitors avoidance in renal transplantation
    • Vincenti F, Ramos E, Brattstrom C, et al,. Multicenter trial exploring calcineurin inhibitors avoidance in renal transplantation. Transplantation 2001; 71: 1282.
    • (2001) Transplantation , vol.71 , pp. 1282
    • Vincenti, F.1    Ramos, E.2    Brattstrom, C.3
  • 6
    • 33747480956 scopus 로고    scopus 로고
    • Calcineurin inhibitor avoidance with daclizumab, mycophenolate mofetil, and prednisolone in DR-matched de novo kidney transplant recipients
    • Asberg A, Midtvedt K, Line PD, et al,. Calcineurin inhibitor avoidance with daclizumab, mycophenolate mofetil, and prednisolone in DR-matched de novo kidney transplant recipients. Transplantation 2006; 82: 62.
    • (2006) Transplantation , vol.82 , pp. 62
    • Asberg, A.1    Midtvedt, K.2    Line, P.D.3
  • 7
    • 38549115640 scopus 로고    scopus 로고
    • Calcineurin inhibitor-sparing regimens in solid organ transplantation: Focus on improving renal function and nephrotoxicity
    • Flechner SM, Kobashigawa J, Klintmalm G,. Calcineurin inhibitor-sparing regimens in solid organ transplantation: focus on improving renal function and nephrotoxicity. Clin Transplant 2008; 22: 1.
    • (2008) Clin Transplant , vol.22 , pp. 1
    • Flechner, S.M.1    Kobashigawa, J.2    Klintmalm, G.3
  • 8
    • 56049102618 scopus 로고    scopus 로고
    • Calcineurin inhibitor sparing in renal transplantation
    • Ekberg H,. Calcineurin inhibitor sparing in renal transplantation. Transplantation 2008; 86: 761.
    • (2008) Transplantation , vol.86 , pp. 761
    • Ekberg, H.1
  • 10
    • 70350131319 scopus 로고    scopus 로고
    • Mycophenolate mofetil and calcineurin-inhibitor reduction: Recent progress
    • Grinyó JM, Cruzado JM,. Mycophenolate mofetil and calcineurin-inhibitor reduction: recent progress. Am J Transplant 2009; 9: 2447.
    • (2009) Am J Transplant , vol.9 , pp. 2447
    • Grinyó, J.M.1    Cruzado, J.M.2
  • 12
    • 77749237077 scopus 로고    scopus 로고
    • MTOR inhibitor/proliferation signal inhibitors: Entering or leaving the field?
    • Rostaing L, Kamar N,. mTOR inhibitor/proliferation signal inhibitors: entering or leaving the field? J Nephrol 2010; 23: 133.
    • (2010) J Nephrol , vol.23 , pp. 133
    • Rostaing, L.1    Kamar, N.2
  • 13
    • 77954952597 scopus 로고    scopus 로고
    • Renal function, efficacy, and safety of sirolimus and mycophenolate mofetil after short-term calcineurin inhibitor-based quadruple therapy in de novo renal transplant patients: One-year analysis of a randomized multicenter trial
    • Guba M, Pratschke J, Hugo C, et al,. Renal function, efficacy, and safety of sirolimus and mycophenolate mofetil after short-term calcineurin inhibitor-based quadruple therapy in de novo renal transplant patients: one-year analysis of a randomized multicenter trial. Transplantation 2010; 90: 175.
    • (2010) Transplantation , vol.90 , pp. 175
    • Guba, M.1    Pratschke, J.2    Hugo, C.3
  • 14
    • 84867098149 scopus 로고    scopus 로고
    • Improved renal function after early conversion from a calcineurin inhibitor to everolimus: A randomized trial in kidney transplantation
    • Mjörnstedt L, Sørensen SS, von Zur Mühlen B, et al,. Improved renal function after early conversion from a calcineurin inhibitor to everolimus: a randomized trial in kidney transplantation. Am J Transplant 2012; 12: 2744.
    • (2012) Am J Transplant , vol.12 , pp. 2744
    • Mjörnstedt, L.1    Sørensen, S.S.2    Von Zur Mühlen, B.3
  • 15
    • 65249134974 scopus 로고    scopus 로고
    • Efficacy and renal function of early conversion from cyclosporine to sirolimus 3 months after renal transplantation: CONCEPT study
    • Lebranchu Y, Thierry A, Toupance O, et al,. Efficacy and renal function of early conversion from cyclosporine to sirolimus 3 months after renal transplantation: CONCEPT study. Am J Transplant 2009; 9: 1115.
    • (2009) Am J Transplant , vol.9 , pp. 1115
    • Lebranchu, Y.1    Thierry, A.2    Toupance, O.3
  • 16
    • 79953243656 scopus 로고    scopus 로고
    • Mycophenolate mofetil-based immunosuppression with sirolimus in renal transplantation: A randomized, controlled Spare-the-Nephron trial
    • Weir MR, Mulgaonkar S, Chan L, et al,. Mycophenolate mofetil-based immunosuppression with sirolimus in renal transplantation: a randomized, controlled Spare-the-Nephron trial. Kidney Int 2011; 79: 897.
    • (2011) Kidney Int , vol.79 , pp. 897
    • Weir, M.R.1    Mulgaonkar, S.2    Chan, L.3
  • 17
    • 79952361568 scopus 로고    scopus 로고
    • Everolimus-based, calcineurin-inhibitor-free regimen in recipients of de-novo kidney transplants: An open-label, randomised, controlled trial
    • Budde K, Becker T, Arns W, et al,. Everolimus-based, calcineurin-inhibitor-free regimen in recipients of de-novo kidney transplants: an open-label, randomised, controlled trial. Lancet 2011; 377: 837.
    • (2011) Lancet , vol.377 , pp. 837
    • Budde, K.1    Becker, T.2    Arns, W.3
  • 18
    • 59649126728 scopus 로고    scopus 로고
    • Conversion from calcineurin inhibitors to sirolimus maintenance therapy in renal allograft recipients: 24-month efficacy and safety results from the CONVERT trial
    • Schena FP, Pascoe MD, Alberu J, et al,. Conversion from calcineurin inhibitors to sirolimus maintenance therapy in renal allograft recipients: 24-month efficacy and safety results from the CONVERT trial. Transplantation 2009; 87: 233.
    • (2009) Transplantation , vol.87 , pp. 233
    • Schena, F.P.1    Pascoe, M.D.2    Alberu, J.3
  • 19
    • 43749098555 scopus 로고    scopus 로고
    • Early, abrupt conversion of de novo renal transplant patients from cyclosporine to everolimus: Results of a pilot study
    • Holdaas H, Bentdal Ø, Pfeffer P, Mjørnstedt L, Solbu D, Midtvedt K,. Early, abrupt conversion of de novo renal transplant patients from cyclosporine to everolimus: results of a pilot study. Clin Transplant 2008; 22: 366.
    • (2008) Clin Transplant , vol.22 , pp. 366
    • Holdaas, H.1    Bentdal Ø2    Pfeffer, P.3    Mjørnstedt, L.4    Solbu, D.5    Midtvedt, K.6
  • 20
    • 84886800500 scopus 로고    scopus 로고
    • Impact of calcineurin-inhibitor conversion to mTOR inhibitor on renal allograft function in a prednisone-free regimen
    • Chhabra D, Alvarado A, Dalal P, et al,. Impact of calcineurin-inhibitor conversion to mTOR inhibitor on renal allograft function in a prednisone-free regimen. Am J Transplant 2013; 13: 2902.
    • (2013) Am J Transplant , vol.13 , pp. 2902
    • Chhabra, D.1    Alvarado, A.2    Dalal, P.3
  • 21
    • 84888371502 scopus 로고    scopus 로고
    • Planned randomized conversion from tacrolimus to sirolimus-based immunosuppressive regimen in de novo kidney transplant recipients
    • Silva HT Jr, Felipe CR, Garcia VD, et al,. Planned randomized conversion from tacrolimus to sirolimus-based immunosuppressive regimen in de novo kidney transplant recipients. Am J Transplant 2013; 13: 3155.
    • (2013) Am J Transplant , vol.13 , pp. 3155
    • Silva, H.T.1    Felipe, C.R.2    Garcia, V.D.3
  • 22
    • 0032910625 scopus 로고    scopus 로고
    • The Banff 97 working classification of renal allograft pathology
    • Racusen LC, Solez K, Colvin RB, et al,. The Banff 97 working classification of renal allograft pathology. Kidney Int 1999; 55: 713.
    • (1999) Kidney Int , vol.55 , pp. 713
    • Racusen, L.C.1    Solez, K.2    Colvin, R.B.3
  • 23
    • 79961039264 scopus 로고    scopus 로고
    • Efficacy and safety of early cyclosporine conversion to sirolimus with continued MMF - Four-year results of the Postconcept study
    • Lebranchu Y, Thierry A, Thervet E, et al,. Efficacy and safety of early cyclosporine conversion to sirolimus with continued MMF-four-year results of the Postconcept study. Am J Transplant 2011; 11: 1665.
    • (2011) Am J Transplant , vol.11 , pp. 1665
    • Lebranchu, Y.1    Thierry, A.2    Thervet, E.3
  • 24
    • 84861793711 scopus 로고    scopus 로고
    • Conversion from cyclosporine to everolimus at 4.5 months posttransplant: 3-year results from the randomized ZEUS study
    • Budde K, Lehner F, Sommerer C, et al,. Conversion from cyclosporine to everolimus at 4.5 months posttransplant: 3-year results from the randomized ZEUS study. Am J Transplant 2012; 12: 1528.
    • (2012) Am J Transplant , vol.12 , pp. 1528
    • Budde, K.1    Lehner, F.2    Sommerer, C.3
  • 25
    • 28544445337 scopus 로고    scopus 로고
    • Superior outcomes in renal transplantation after early cyclosporine withdrawal and sirolimus maintenance therapy, regardless of baseline renal function
    • Russ G, Segoloni G, Oberbauer R, et al,. Superior outcomes in renal transplantation after early cyclosporine withdrawal and sirolimus maintenance therapy, regardless of baseline renal function. Transplantation 2005; 80: 1204.
    • (2005) Transplantation , vol.80 , pp. 1204
    • Russ, G.1    Segoloni, G.2    Oberbauer, R.3
  • 26
    • 80054988911 scopus 로고    scopus 로고
    • Estimating glomerular filtration rate in kidney transplant recipients: Performance over time of four creatinine-based formulas
    • Buron F, Hadj-Aissa A, Dubourg L, Morelon E, Steghens JP, Ducher M, Fauvel JP,. Estimating glomerular filtration rate in kidney transplant recipients: performance over time of four creatinine-based formulas. Transplantation 2011; 92: 1005.
    • (2011) Transplantation , vol.92 , pp. 1005
    • Buron, F.1    Hadj-Aissa, A.2    Dubourg, L.3    Morelon, E.4    Steghens, J.P.5    Ducher, M.6    Fauvel, J.P.7
  • 27
    • 43849101666 scopus 로고    scopus 로고
    • Performance of creatinine-based estimates of GFR in kidney transplant recipients: A systematic review
    • White CA, Huang D, Akbari A, Garland J, Knoll GA,. Performance of creatinine-based estimates of GFR in kidney transplant recipients: a systematic review. Am J Kidney Dis 2008; 51: 1005.
    • (2008) Am J Kidney Dis , vol.51 , pp. 1005
    • White, C.A.1    Huang, D.2    Akbari, A.3    Garland, J.4    Knoll, G.A.5
  • 28
    • 0032983478 scopus 로고    scopus 로고
    • Screening for basiliximab exposure-response relationships in renal allotransplantation
    • Kovarik JM, Moore R, Wolf P, et al,. Screening for basiliximab exposure-response relationships in renal allotransplantation. Clin Transplant 1999; 13: 32.
    • (1999) Clin Transplant , vol.13 , pp. 32
    • Kovarik, J.M.1    Moore, R.2    Wolf, P.3
  • 29
    • 74049137551 scopus 로고    scopus 로고
    • Noncanonical TGF-b pathways, mTORC1 and Ab1, in renal interstitial fibrogenesis
    • Wang S, Wilkes MC, Leof EB, Hirschberg R., Noncanonical TGF-b pathways, mTORC1 and Ab1, in renal interstitial fibrogenesis. Am J Physiol Renal Physiol 2010; 298: F142.
    • (2010) Am J Physiol Renal Physiol , vol.298 , pp. F142
    • Wang, S.1    Wilkes, M.C.2    Leof, E.B.3    Hirschberg, R.4
  • 30
    • 38149095060 scopus 로고    scopus 로고
    • Rapamycin inhibits PAI-1 expression and reduces interstitial fibrosis and glomerulosclerosis in chronic allograft nephropathy
    • Pontrelli P, Rossini M, Infante B, et al,. Rapamycin inhibits PAI-1 expression and reduces interstitial fibrosis and glomerulosclerosis in chronic allograft nephropathy. Transplantation 2008; 85: 125.
    • (2008) Transplantation , vol.85 , pp. 125
    • Pontrelli, P.1    Rossini, M.2    Infante, B.3
  • 31
    • 70350126186 scopus 로고    scopus 로고
    • Interstitial fibrosis quantification in renal transplant recipients randomized to continue cyclosporine or convert to sirolimus
    • Servais A, Meas-Yedid V, Toupance O, et al,. Interstitial fibrosis quantification in renal transplant recipients randomized to continue cyclosporine or convert to sirolimus. Am J Transplant 2009; 9: 2552.
    • (2009) Am J Transplant , vol.9 , pp. 2552
    • Servais, A.1    Meas-Yedid, V.2    Toupance, O.3
  • 32
    • 77956222223 scopus 로고    scopus 로고
    • Progression of graft fibrosis under mammalian target of rapamycin inhibitor-based regimen
    • Yilmaz M, Nart A, Sen S, et al,. Progression of graft fibrosis under mammalian target of rapamycin inhibitor-based regimen. Nephrology (Carlton) 2010; 15: 653.
    • (2010) Nephrology (Carlton) , vol.15 , pp. 653
    • Yilmaz, M.1    Nart, A.2    Sen, S.3
  • 33
    • 84878644009 scopus 로고    scopus 로고
    • Incidence of donor-specific antibodies in kidney transplant patients following conversion to an everolimus-based calcineurin inhibitor-free regimen
    • Kamar N, Del Bello A, Congy-Jolivet N, et al,. Incidence of donor-specific antibodies in kidney transplant patients following conversion to an everolimus-based calcineurin inhibitor-free regimen. Clin Transplant 2013; 27: 455.
    • (2013) Clin Transplant , vol.27 , pp. 455
    • Kamar, N.1    Del Bello, A.2    Congy-Jolivet, N.3
  • 34
    • 84860431997 scopus 로고    scopus 로고
    • Donor-specific HLA antibodies in a cohort comparing everolimus with cyclosporine after kidney transplantation
    • Liefeldt L, Brakemeier S, Glander P, et al,. Donor-specific HLA antibodies in a cohort comparing everolimus with cyclosporine after kidney transplantation. Am J Transplant 2012; 12: 1192.
    • (2012) Am J Transplant , vol.12 , pp. 1192
    • Liefeldt, L.1    Brakemeier, S.2    Glander, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.