4-(1H-imidazol-1-yl) aniline: A new ligand of mixed-mode chromatography for antibody purification

Journal of Chromatography A

Volumn 1216, Issue 33, 2009, Pages 6081-6087

  Shi, Qing Hong ^a   Cheng, Zheng ^a   Sun, Yan ^a  

^a TIANJIN UNIVERSITY   (China)

Author keywords

Albumin; Antibody; Dual selectivity; Ligand; Mixed mode chromatography; Purification

Indexed keywords

ADSORPTION EQUILIBRIA; ALBUMIN; ANTIBODY PURIFICATION; BINDING SELECTIVITY; BINDING STUDIES; BOVINE SERUM; BOVINE SERUM ALBUMINS; CHARGE TRANSFER INTERACTION; DUAL-SELECTIVITY; DYNAMIC BINDING CAPACITY; FRONTAL ANALYSIS; HYDROGEN BONDINGS; HYDROPHOBIC INTERACTIONS; IMIDAZOL; IMMUNOGLOBULIN G; LIGAND-PROTEIN INTERACTION; MIXED-MODE CHROMATOGRAPHY; PH VALUE; PURIFICATION FACTORS; SALT CONCENTRATION; SALT TOLERANCE;

ADSORPTION; ANILINE; ANTIBODIES; CHARGE TRANSFER; CHROMATOGRAPHIC ANALYSIS; DESORPTION; GEL PERMEATION CHROMATOGRAPHY; HYDROGEN; HYDROGEN BONDS; HYDROPHOBIC CHROMATOGRAPHY; HYDROPHOBICITY; ION EXCHANGE; LIGANDS; NEGATIVE IONS; PURIFICATION; SODIUM CHLORIDE;

BODY FLUIDS;

4 (1H IMIDAZOL 1 YL)ANILINE; ANILINE DERIVATIVE; BOVINE SERUM ALBUMIN; IMMUNOGLOBULIN G; LIGAND; SEPHAROSE; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ADSORPTION; ANTIGEN BINDING; ARTICLE; CHROMATOGRAPHY; CONTROLLED STUDY; ELUTION; HYDROGEN BOND; HYDROPHOBICITY; LIGAND BINDING; MIXED MODE CHROMATOGRAPHY; PH; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN PURIFICATION;

ANILINE COMPOUNDS; CHROMATOGRAPHY, AFFINITY; CHROMATOGRAPHY, AGAROSE; HYDROGEN-ION CONCENTRATION; IMIDAZOLES; IMMUNOGLOBULIN G; LIGANDS; OSMOLAR CONCENTRATION; PROTEIN BINDING; SEPHAROSE;

BOVINAE;

EID: 67650932899     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2009.06.065     Document Type: Article

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