메뉴 건너뛰기




Volumn 121, Issue s5, 2014, Pages 62-69

Beyond HIV microbicides: Multipurpose prevention technology products

Author keywords

combination products; contraception; microbicide; MPTs

Indexed keywords

ASTODRIMER; CARRAGEENAN; CONTRACEPTIVE AGENT; DAPIVIRINE; ETONOGESTREL; MARAVIROC; MEDROXYPROGESTERONE ACETATE; MICROBICIDE; N [3 [4 (3 BENZYL 1 ETHYL 5 PYRAZOLYL) 1 PIPERIDINYLMETHYL] 4 (3 FLUOROPHENYL)CYCLOPENTYL] N METHYLVALINE; PRO 2000; PROTEINASE INHIBITOR; RECOMBINANT PROTEIN; RNA DIRECTED DNA POLYMERASE INHIBITOR; SPERMICIDAL AGENT; VACCINE; DRUG COMBINATION;

EID: 84916214797     PISSN: 14700328     EISSN: 14710528     Source Type: Journal    
DOI: 10.1111/1471-0528.12852     Document Type: Review
Times cited : (30)

References (58)
  • 1
    • 77955930318 scopus 로고    scopus 로고
    • Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women
    • Abdool Karim Q, Abdool Karim S, Frohlich JA, Grobler AC, Baxter C, Mansoor LE, et al. Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women. Science 2010; 329: 1168-74.
    • (2010) Science , vol.329 , pp. 1168-1174
    • Abdool Karim, Q.1    Abdool Karim, S.2    Frohlich, J.A.3    Grobler, A.C.4    Baxter, C.5    Mansoor, L.E.6
  • 2
    • 78649393167 scopus 로고    scopus 로고
    • Combining prevention of HIV-1, other sexually transmitted infections and unintended pregnancies: Development of dual-protection technologies
    • Friend DR, Doncel GF,. Combining prevention of HIV-1, other sexually transmitted infections and unintended pregnancies: development of dual-protection technologies. Antiviral Res 2010; 88: S47-54.
    • (2010) Antiviral Res , vol.88 , pp. S47-S54
    • Friend, D.R.1    Doncel, G.F.2
  • 3
    • 84858970174 scopus 로고    scopus 로고
    • Intravaginal rings: Controlled release systems for contraception and prevention of transmission of sexually transmitted infections
    • Friend DR,. Intravaginal rings: controlled release systems for contraception and prevention of transmission of sexually transmitted infections. Drug Delivery Trans Res 2011; 1: 185-93.
    • (2011) Drug Delivery Trans Res , vol.1 , pp. 185-193
    • Friend, D.R.1
  • 4
    • 84858809948 scopus 로고    scopus 로고
    • Drug delivery in multiple indication (multipurpose) prevention technologies: Systems to prevent HIV-1 transmission and unintended pregnancies or HSV-2 transmission
    • Friend DR,. Drug delivery in multiple indication (multipurpose) prevention technologies: systems to prevent HIV-1 transmission and unintended pregnancies or HSV-2 transmission. Expert Opin Drug Deliv 2012; 9: 417-27.
    • (2012) Expert Opin Drug Deliv , vol.9 , pp. 417-427
    • Friend, D.R.1
  • 6
    • 76449108237 scopus 로고    scopus 로고
    • Multipurpose prevention technologies for sexual and reproductive health: Gaining momentum and promise
    • Holt BY, Kilbourne-Brook M, Stone A, Harrison P, Shields WC,. Multipurpose prevention technologies for sexual and reproductive health: gaining momentum and promise. Contraception 2010; 81: 177-80.
    • (2010) Contraception , vol.81 , pp. 177-180
    • Holt, B.Y.1    Kilbourne-Brook, M.2    Stone, A.3    Harrison, P.4    Shields, W.C.5
  • 7
    • 84883448628 scopus 로고    scopus 로고
    • Delivering on MPTs: Addressing the needs, rising to the challenges and making the opportunities
    • Malcolm RK, Fetherston SM,. Delivering on MPTs: addressing the needs, rising to the challenges and making the opportunities. Contraception 2013; 88: 321-5.
    • (2013) Contraception , vol.88 , pp. 321-325
    • Malcolm, R.K.1    Fetherston, S.M.2
  • 8
    • 80053489212 scopus 로고    scopus 로고
    • Multipurpose prevention technologies: Biomedical tools to prevent HIV-1, HSV-2, and unintended pregnancies
    • Thurman AR, Clark MR, Doncel GF,. Multipurpose prevention technologies: biomedical tools to prevent HIV-1, HSV-2, and unintended pregnancies. Infect Dis Obstet Gynecol 2011; 2011: 1-10.
    • (2011) Infect Dis Obstet Gynecol , vol.2011 , pp. 1-10
    • Thurman, A.R.1    Clark, M.R.2    Doncel, G.F.3
  • 9
    • 84867046708 scopus 로고    scopus 로고
    • Herpes simplex virus and HIV: Genital infection synergy and novel approaches to dual prevention
    • Thurman AR, Doncel GF,. Herpes simplex virus and HIV: genital infection synergy and novel approaches to dual prevention. Int J STD AIDS 2012; 23: 613-9.
    • (2012) Int J STD AIDS , vol.23 , pp. 613-619
    • Thurman, A.R.1    Doncel, G.F.2
  • 10
    • 78649419410 scopus 로고    scopus 로고
    • Novel approaches to vaginal delivery and safety of microbicides: Biopharmaceuticals, nanoparticles, and vaccines
    • Whaley KJ, Hanes J, Shattock R, Cone RA, Friend DR,. Novel approaches to vaginal delivery and safety of microbicides: biopharmaceuticals, nanoparticles, and vaccines. Antiviral Res 2010; 88: S55-6.
    • (2010) Antiviral Res , vol.88 , pp. S55-S56
    • Whaley, K.J.1    Hanes, J.2    Shattock, R.3    Cone, R.A.4    Friend, D.R.5
  • 11
    • 80054887588 scopus 로고    scopus 로고
    • Topical tenofovir, a microbicide effective against HIV, inhibits herpes simplex virus-2 replication
    • Andrei G, Lisco A, Vanpouille C, Introini A, Balestra E, van den Oord J, et al. Topical tenofovir, a microbicide effective against HIV, inhibits herpes simplex virus-2 replication. Cell Host Microbe 2011; 10: 379-89.
    • (2011) Cell Host Microbe , vol.10 , pp. 379-389
    • Andrei, G.1    Lisco, A.2    Vanpouille, C.3    Introini, A.4    Balestra, E.5    Van Den Oord, J.6
  • 12
    • 84870318366 scopus 로고    scopus 로고
    • Drug-eluting fibers for HIV-1 inhibition and contraception
    • Ball C, Krogstad E, Chaowanachan T, Woodrow KA,. Drug-eluting fibers for HIV-1 inhibition and contraception. PLoS ONE 2012; 7: e49792.
    • (2012) PLoS ONE , vol.7 , pp. e49792
    • Ball, C.1    Krogstad, E.2    Chaowanachan, T.3    Woodrow, K.A.4
  • 13
    • 84879071769 scopus 로고    scopus 로고
    • A modified SILCS contraceptive diaphragm for long-term controlled release of the HIV microbicide dapivirine
    • Major I, Boyd P, Kilbourne-Brook M, Saxon G, Cohen J, Malcolm RK,. A modified SILCS contraceptive diaphragm for long-term controlled release of the HIV microbicide dapivirine. Contraception 2013; 88: 58-66.
    • (2013) Contraception , vol.88 , pp. 58-66
    • Major, I.1    Boyd, P.2    Kilbourne-Brook, M.3    Saxon, G.4    Cohen, J.5    Malcolm, R.K.6
  • 14
    • 84862678558 scopus 로고    scopus 로고
    • Intravaginal ring delivery of tenofovir disoproxil fumarate for prevention of HIV and herpes simplex virus infection
    • Mesquita PM, Rastogi R, Segarra TJ, Teller RS, Torres NM, Huber AM, et al. Intravaginal ring delivery of tenofovir disoproxil fumarate for prevention of HIV and herpes simplex virus infection. J Antimicrob Chemother 2012; 67: 1730-8.
    • (2012) J Antimicrob Chemother , vol.67 , pp. 1730-1738
    • Mesquita, P.M.1    Rastogi, R.2    Segarra, T.J.3    Teller, R.S.4    Torres, N.M.5    Huber, A.M.6
  • 15
    • 84880304261 scopus 로고    scopus 로고
    • Pharmacokinetics of a multipurpose pod-intravaginal ring simultaneously delivering five drugs in an ovine model
    • Moss JA, Malone AM, Smith TJ, Kennedy S, Nguyen C, Vincent KL, et al. Pharmacokinetics of a multipurpose pod-intravaginal ring simultaneously delivering five drugs in an ovine model. Antimicrob Agents Chemother 2013; 57: 3994-7.
    • (2013) Antimicrob Agents Chemother , vol.57 , pp. 3994-3997
    • Moss, J.A.1    Malone, A.M.2    Smith, T.J.3    Kennedy, S.4    Nguyen, C.5    Vincent, K.L.6
  • 16
    • 80051629593 scopus 로고    scopus 로고
    • Combination drugs - Hype, harm, and hope
    • Podolsky SH, Greene JA,. Combination drugs-hype, harm, and hope. N Engl J Med 2011; 365: 488-91.
    • (2011) N Engl J Med , vol.365 , pp. 488-491
    • Podolsky, S.H.1    Greene, J.A.2
  • 17
    • 84916243699 scopus 로고    scopus 로고
    • Developing combination drugs in preclinical studies
    • Jean-Charles G. editor. Berlin: Springer;
    • Lodola A,. Developing combination drugs in preclinical studies. In:, Jean-Charles G, editor. Drug Safety Evaluation: Methods and Protocols, Methods in Molecular Biology, vol. 691. Berlin: Springer; 2009. pp. 3-16.
    • (2009) Drug Safety Evaluation: Methods and Protocols, Methods in Molecular Biology , vol.691 , pp. 3-16
    • Lodola, A.1
  • 18
    • 34250179723 scopus 로고    scopus 로고
    • Fixed-dose combinations improve medication compliance: A meta-analysis
    • Bangalore S, Kamalakkannan G, Parkar S, Messerli FH,. Fixed-dose combinations improve medication compliance: a meta-analysis. Am J Med 2007; 120: 713-9.
    • (2007) Am J Med , vol.120 , pp. 713-719
    • Bangalore, S.1    Kamalakkannan, G.2    Parkar, S.3    Messerli, F.H.4
  • 19
    • 42449099867 scopus 로고    scopus 로고
    • Impact of fixed-dose combination drugs on adherence to prescription medications
    • Pan F, Chernew ME, Fendrick AM,. Impact of fixed-dose combination drugs on adherence to prescription medications. J Gen Intern Med 2008; 23: 611-4.
    • (2008) J Gen Intern Med , vol.23 , pp. 611-614
    • Pan, F.1    Chernew, M.E.2    Fendrick, A.M.3
  • 20
    • 84877948208 scopus 로고    scopus 로고
    • The economics of polypharmacology: Fixed dose combinations and drug cocktails
    • Wertheimer AI,. The economics of polypharmacology: fixed dose combinations and drug cocktails. Curr Med Chem 2013; 20: 1635-8.
    • (2013) Curr Med Chem , vol.20 , pp. 1635-1638
    • Wertheimer, A.I.1
  • 23
    • 84872376829 scopus 로고    scopus 로고
    • A silicone elastomer vaginal ring for HIV prevention containing two microbicides with different mechanisms of action
    • Fetherston SM, Boyd P, McCoy CF, McBride MC, Edwards KL, Ampofo S, et al. A silicone elastomer vaginal ring for HIV prevention containing two microbicides with different mechanisms of action. Eur J Pharm Sci 2012; 48: 406-15.
    • (2012) Eur J Pharm Sci , vol.48 , pp. 406-415
    • Fetherston, S.M.1    Boyd, P.2    McCoy, C.F.3    McBride, M.C.4    Edwards, K.L.5    Ampofo, S.6
  • 24
    • 81255157679 scopus 로고    scopus 로고
    • Non-aqueous silicone elastomer gels as a vaginal microbicide delivery system for the HIV-1 entry inhibitor maraviroc
    • Forbes CJ, Lowry D, Geer L, Veazey RS, Shattock RJ, Klasse PJ, et al. Non-aqueous silicone elastomer gels as a vaginal microbicide delivery system for the HIV-1 entry inhibitor maraviroc. J Control Release 2011; 156: 161-9.
    • (2011) J Control Release , vol.156 , pp. 161-169
    • Forbes, C.J.1    Lowry, D.2    Geer, L.3    Veazey, R.S.4    Shattock, R.J.5    Klasse, P.J.6
  • 27
    • 46249087616 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 (HIV-1) integration: A potential target for microbicides to prevent cell-free or cell-associated HIV-1 infection
    • Terrazas-Aranda K, Van Herrewege Y, Hazuda D, Lewi P, Costi R, Di Santo R, et al. Human immunodeficiency virus type 1 (HIV-1) integration: a potential target for microbicides to prevent cell-free or cell-associated HIV-1 infection. Antimicrob Agents Chemother 2008; 52: 2544-54.
    • (2008) Antimicrob Agents Chemother , vol.52 , pp. 2544-2554
    • Terrazas-Aranda, K.1    Van Herrewege, Y.2    Hazuda, D.3    Lewi, P.4    Costi, R.5    Di Santo, R.6
  • 28
    • 84857125406 scopus 로고    scopus 로고
    • Potential use of protease inhibitors as vaginal and colorectal microbicides
    • Herrera C, Shattock RJ,. Potential use of protease inhibitors as vaginal and colorectal microbicides. Curr HIV Res 2012; 10: 42-52.
    • (2012) Curr HIV Res , vol.10 , pp. 42-52
    • Herrera, C.1    Shattock, R.J.2
  • 29
    • 84872028026 scopus 로고    scopus 로고
    • MiniCD4 microbicide prevents HIV infection of human mucosal explants and vaginal transmission of SHIV162P3 in cynomolgus macaques
    • Dereuddre-Bosquet N, Morellato-Castillo L, Brouwers J, Augustijns P, Bouchemal K, Ponchel G, et al. MiniCD4 microbicide prevents HIV infection of human mucosal explants and vaginal transmission of SHIV162P3 in cynomolgus macaques. PLoS Pathog 2012; 8: e10030.
    • (2012) PLoS Pathog , vol.8 , pp. e10030
    • Dereuddre-Bosquet, N.1    Morellato-Castillo, L.2    Brouwers, J.3    Augustijns, P.4    Bouchemal, K.5    Ponchel, G.6
  • 30
    • 84881599224 scopus 로고    scopus 로고
    • Peptide and protein-based inhibitors of HIV-1 co-receptors
    • Recum HA, Pokorski JK,. Peptide and protein-based inhibitors of HIV-1 co-receptors. Exp Biol Med 2013; 238: 442-9.
    • (2013) Exp Biol Med , vol.238 , pp. 442-449
    • Recum, H.A.1    Pokorski, J.K.2
  • 32
    • 38949198100 scopus 로고    scopus 로고
    • VivaGel (SPL7013 Gel): A candidate dendrimer-microbicide for the prevention of HIV and HSV infection
    • Rupp R, Rosenthal SL, Stanberry LR,. VivaGel (SPL7013 Gel): a candidate dendrimer-microbicide for the prevention of HIV and HSV infection. Int J Nanomedicine 2007; 2007: 561-6.
    • (2007) Int J Nanomedicine , vol.2007 , pp. 561-566
    • Rupp, R.1    Rosenthal, S.L.2    Stanberry, L.R.3
  • 33
    • 80052844387 scopus 로고    scopus 로고
    • ®) retains potent HIV-1 and HSV-2 inhibitory activity following vaginal administration in humans
    • ®) retains potent HIV-1 and HSV-2 inhibitory activity following vaginal administration in humans. PLoS ONE 2011; 6: e24095.
    • (2011) PLoS ONE , vol.6 , pp. e24095
    • Price, C.F.1    Tyssen, D.2    Sonza, S.3    Davie, A.4    Evans, S.5    Lewis, G.R.6
  • 34
  • 35
    • 84861885292 scopus 로고    scopus 로고
    • Macaque studies of vaccine and microbicide combinations for preventing HIV-1 sexual transmission
    • Barouch DH, Klasse PJ, Dufour J, Veazey RS, Moore JP,. Macaque studies of vaccine and microbicide combinations for preventing HIV-1 sexual transmission. Proc Natl Acad Sci USA 2012; 109: 8694-8.
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 8694-8698
    • Barouch, D.H.1    Klasse, P.J.2    Dufour, J.3    Veazey, R.S.4    Moore, J.P.5
  • 39
    • 77955133374 scopus 로고    scopus 로고
    • Toward an information-motivation-behavioral skills model of microbicide adherence in clinical trials
    • Ferrer RA, Morrow KM, Fisher WA, Fisher JD,. Toward an information-motivation-behavioral skills model of microbicide adherence in clinical trials. AIDS Care 2010; 22: 997-1005.
    • (2010) AIDS Care , vol.22 , pp. 997-1005
    • Ferrer, R.A.1    Morrow, K.M.2    Fisher, W.A.3    Fisher, J.D.4
  • 41
    • 84858804932 scopus 로고    scopus 로고
    • State of the art in intravaginal ring technology for topical prophylaxis of HIV infection
    • Kiser PF, Johnson TJ, Clark JT,. State of the art in intravaginal ring technology for topical prophylaxis of HIV infection. AIDS Rev 2012; 14: 62-77.
    • (2012) AIDS Rev , vol.14 , pp. 62-77
    • Kiser, P.F.1    Johnson, T.J.2    Clark, J.T.3
  • 43
    • 84884555284 scopus 로고    scopus 로고
    • Assessment of topical microbicides to prevent HIV-1 transmission: Concepts, testing, lessons learned
    • Friend DR, Kiser PF,. Assessment of topical microbicides to prevent HIV-1 transmission: concepts, testing, lessons learned. Antiviral Res 2013; 99: 391-400.
    • (2013) Antiviral Res , vol.99 , pp. 391-400
    • Friend, D.R.1    Kiser, P.F.2
  • 45
    • 33750012577 scopus 로고    scopus 로고
    • Intravaginal ring delivery of the reverse transcriptase inhibitor TMC 120 as an HIV microbicide
    • Woolfson AD, Malcolm RK, Morrow RJ, Toner CF, McCullagh SD,. Intravaginal ring delivery of the reverse transcriptase inhibitor TMC 120 as an HIV microbicide. Int J Pharm 2006; 325: 82-9.
    • (2006) Int J Pharm , vol.325 , pp. 82-89
    • Woolfson, A.D.1    Malcolm, R.K.2    Morrow, R.J.3    Toner, C.F.4    McCullagh, S.D.5
  • 46
    • 68049121905 scopus 로고    scopus 로고
    • Safety and pharmacokinetics of dapivirine delivery from matrix and reservoir intravaginal rings to HIV-negative women
    • Nel A, Smythe S, Young K, Malcolm K, McCoy C, Rosenberg Z, et al. Safety and pharmacokinetics of dapivirine delivery from matrix and reservoir intravaginal rings to HIV-negative women. J Acquir Immune Defic Syndr 2009; 51: 416-23.
    • (2009) J Acquir Immune Defic Syndr , vol.51 , pp. 416-423
    • Nel, A.1    Smythe, S.2    Young, K.3    Malcolm, K.4    McCoy, C.5    Rosenberg, Z.6
  • 47
    • 34250673216 scopus 로고    scopus 로고
    • Factors associated with willingness to use the contraceptive vaginal ring
    • Gilliam M, Holmquist S, Berlin A,. Factors associated with willingness to use the contraceptive vaginal ring. Contraception 2007; 76: 30-4.
    • (2007) Contraception , vol.76 , pp. 30-34
    • Gilliam, M.1    Holmquist, S.2    Berlin, A.3
  • 48
    • 34447511281 scopus 로고    scopus 로고
    • Delivery of microbicides to the vagina: Difficulties reported with the use of three devices, adherence to use and preferences
    • Hardy E, Hebling EM, Sousa MH, Almeida AF, Amaral E,. Delivery of microbicides to the vagina: difficulties reported with the use of three devices, adherence to use and preferences. Contraception 2007; 76: 126-31.
    • (2007) Contraception , vol.76 , pp. 126-131
    • Hardy, E.1    Hebling, E.M.2    Sousa, M.H.3    Almeida, A.F.4    Amaral, E.5
  • 49
    • 0030711089 scopus 로고    scopus 로고
    • Effect of different insertion regimens on side effects with a combination contraceptive vaginal ring
    • Weisberg E, Fraser IS, Lacarra M, Mishell DR, Jackanicz T,. Effect of different insertion regimens on side effects with a combination contraceptive vaginal ring. Contraception 1997; 56: 233-9.
    • (1997) Contraception , vol.56 , pp. 233-239
    • Weisberg, E.1    Fraser, I.S.2    Lacarra, M.3    Mishell, D.R.4    Jackanicz, T.5
  • 51
    • 0037004986 scopus 로고    scopus 로고
    • High acceptability and satisfaction with NuvaRing use
    • discussion 37-9
    • Szarewski A,. High acceptability and satisfaction with NuvaRing use. Eur J Contracept Reprod Health Care 2002; 7 (Suppl 2): 31-6; discussion 37-9.
    • (2002) Eur J Contracept Reprod Health Care , vol.7 , pp. 31-36
    • Szarewski, A.1
  • 53
    • 0141459442 scopus 로고    scopus 로고
    • Efficacy and tolerability of a novel estradiol vaginal ring for relief of menopausal symptoms
    • Speroff L,. Efficacy and tolerability of a novel estradiol vaginal ring for relief of menopausal symptoms. Obstet Gynecol 2003; 102: 823-34.
    • (2003) Obstet Gynecol , vol.102 , pp. 823-834
    • Speroff, L.1
  • 54
    • 0035103518 scopus 로고    scopus 로고
    • Efficacy, tolerability and acceptability of a novel contraceptive vaginal ring releasing etonogestrel and ethinyl oestradiol
    • Roumen FJ, Apter D, Mulders TM, Dieben TO,. Efficacy, tolerability and acceptability of a novel contraceptive vaginal ring releasing etonogestrel and ethinyl oestradiol. Hum Reprod 2001; 16: 469-75.
    • (2001) Hum Reprod , vol.16 , pp. 469-475
    • Roumen, F.J.1    Apter, D.2    Mulders, T.M.3    Dieben, T.O.4
  • 55
    • 0036709915 scopus 로고    scopus 로고
    • Efficacy, cycle control, and user acceptability of a novel combined contraceptive vaginal ring
    • Dieben TOM, Roumen FJME, Apter D,. Efficacy, cycle control, and user acceptability of a novel combined contraceptive vaginal ring. Obstet Gynecol 2002; 100: 585-93.
    • (2002) Obstet Gynecol , vol.100 , pp. 585-593
    • Dieben, T.O.M.1    Roumen, F.2    Apter, D.3
  • 56
    • 0033005847 scopus 로고    scopus 로고
    • Clinical acceptability of an ethylene-vinyl-acetate nonmedicated vaginal ring
    • Roumen FJ, Dieben TO,. Clinical acceptability of an ethylene-vinyl-acetate nonmedicated vaginal ring. Contraception 1999; 59: 59-62.
    • (1999) Contraception , vol.59 , pp. 59-62
    • Roumen, F.J.1    Dieben, T.O.2
  • 57
    • 0043201350 scopus 로고    scopus 로고
    • The effect of a novel vaginal ring delivering oestradiol acetate on climacteric symptoms in postmenopausal women
    • Buckler H, Al-Azzawi F,. The effect of a novel vaginal ring delivering oestradiol acetate on climacteric symptoms in postmenopausal women. BJOG 2003; 110: 753-9.
    • (2003) BJOG , vol.110 , pp. 753-759
    • Buckler, H.1    Al-Azzawi, F.2
  • 58
    • 75149116238 scopus 로고    scopus 로고
    • Segmented polyurethane intravaginal rings for the sustained combined delivery of antiretroviral agents dapivirine and tenofovir
    • Johnson TJ, Gupta KM, Fabian J, Albright TH, Kiser PF,. Segmented polyurethane intravaginal rings for the sustained combined delivery of antiretroviral agents dapivirine and tenofovir. Eur J Pharm Sci 2010; 39: 203-12.
    • (2010) Eur J Pharm Sci , vol.39 , pp. 203-212
    • Johnson, T.J.1    Gupta, K.M.2    Fabian, J.3    Albright, T.H.4    Kiser, P.F.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.