메뉴 건너뛰기




Volumn 67, Issue 7, 2012, Pages 1730-1738

Intravaginal ring delivery of tenofovir disoproxil fumarate for prevention of HIV and herpes simplex virus infection

Author keywords

Microbicides; NRTIs; PrEP

Indexed keywords

ACICLOVIR; ETHYLENE VINYL ACETATE COPOLYMER; POLYETHERURETHAN; SILICONE; TENOFOVIR; TENOFOVIR DISOPROXIL;

EID: 84862678558     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dks097     Document Type: Article
Times cited : (80)

References (36)
  • 1
    • 77955930318 scopus 로고    scopus 로고
    • Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women
    • Abdool Karim Q, Abdool Karim SS, Frohlich JA et al. Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women. Science 2010; 329: 1168-74.
    • (2010) Science , vol.329 , pp. 1168-1174
    • Abdool Karim, Q.1    Abdool Karim, S.S.2    Frohlich, J.A.3
  • 2
    • 0027534661 scopus 로고
    • Differential antiherpesvirus and antiretrovirus effects of the (S) and (R) enantiomers of acyclic nucleoside phosphonates: potent and selective in vitro and in vivo antiretrovirus activities of (R)-9-(2-phosphonomethoxypropyl)-2,6-diaminopurine
    • Balzarini J, Holy A, Jindrich J et al. Differential antiherpesvirus and antiretrovirus effects of the (S) and (R) enantiomers of acyclic nucleoside phosphonates: potent and selective in vitro and in vivo antiretrovirus activities of (R)-9-(2-phosphonomethoxypropyl)-2,6-diaminopurine. Antimicrob Agents Chemother 1993; 37: 332-8.
    • (1993) Antimicrob Agents Chemother , vol.37 , pp. 332-338
    • Balzarini, J.1    Holy, A.2    Jindrich, J.3
  • 3
    • 80054887588 scopus 로고    scopus 로고
    • Topical tenofovir, a microbicide effective against HIV, inhibits herpes simplex virus-2 replication
    • Andrei G, Lisco A, Vanpouille C et al. Topical tenofovir, a microbicide effective against HIV, inhibits herpes simplex virus-2 replication. Cell Host Microbe 2011; 10: 379-89.
    • (2011) Cell Host Microbe , vol.10 , pp. 379-389
    • Andrei, G.1    Lisco, A.2    Vanpouille, C.3
  • 4
    • 79551614982 scopus 로고    scopus 로고
    • Female genital tract secretions and semen impact the development of microbicides for the prevention of HIV and other sexually transmitted infections
    • Herold BC, Mesquita PM, Madan RP et al. Female genital tract secretions and semen impact the development of microbicides for the prevention of HIV and other sexually transmitted infections. Am J Reprod Immunol 2011; 65: 325-33.
    • (2011) Am J Reprod Immunol , vol.65 , pp. 325-333
    • Herold, B.C.1    Mesquita, P.M.2    Madan, R.P.3
  • 6
    • 49149115228 scopus 로고    scopus 로고
    • An evaluation of intravaginal rings as a potential HIV prevention device in urban Kenya: behaviors and attitudes that might influence uptake within a high-risk population
    • Smith DJ, Wakasiaka S, Hoang TD et al. An evaluation of intravaginal rings as a potential HIV prevention device in urban Kenya: behaviors and attitudes that might influence uptake within a high-risk population. J Womens Health (Larchmt) 2008; 17: 1025-34.
    • (2008) J Womens Health (Larchmt) , vol.17 , pp. 1025-1034
    • Smith, D.J.1    Wakasiaka, S.2    Hoang, T.D.3
  • 7
    • 75149116238 scopus 로고    scopus 로고
    • Segmented polyurethane intravaginal rings for the sustained combined delivery of antiretroviral agents dapivirine and tenofovir
    • Johnson TJ, Gupta KM, Fabian J et al. Segmented polyurethane intravaginal rings for the sustained combined delivery of antiretroviral agents dapivirine and tenofovir. Eur J Pharm Sci 2010; 39: 203-12.
    • (2010) Eur J Pharm Sci , vol.39 , pp. 203-212
    • Johnson, T.J.1    Gupta, K.M.2    Fabian, J.3
  • 8
    • 78649398535 scopus 로고    scopus 로고
    • Advances in microbicide vaginal rings
    • Malcolm RK, Edwards KL, Kiser P et al. Advances in microbicide vaginal rings. Antiviral Res 2010; 88 Suppl 1: S30-9.
    • (2010) Antiviral Res , vol.88 , Issue.SUPPL. 1
    • Malcolm, R.K.1    Edwards, K.L.2    Kiser, P.3
  • 9
    • 84858804932 scopus 로고    scopus 로고
    • State of the art in intravaginal ring technology for topical prophylaxis of HIV infection
    • Kiser PF, Johnson TJ, Clark JT. State of the art in intravaginal ring technology for topical prophylaxis of HIV infection. AIDS Rev 2012; 14: 62-77.
    • (2012) AIDS Rev , vol.14 , pp. 62-77
    • Kiser, P.F.1    Johnson, T.J.2    Clark, J.T.3
  • 10
    • 0033531315 scopus 로고    scopus 로고
    • The influence of composition ratio on the morphology of biomedical polyurethanes
    • Martin DJ, Meijs GF, Gunatillake PA et al. The influence of composition ratio on the morphology of biomedical polyurethanes. J Appl Polym Sci 1999; 71: 937-52.
    • (1999) J Appl Polym Sci , vol.71 , pp. 937-952
    • Martin, D.J.1    Meijs, G.F.2    Gunatillake, P.A.3
  • 11
    • 84962259981 scopus 로고    scopus 로고
    • Case study: tenofovir disoproxil fumarate: an oral prodrug of tenofovir
    • Borchardt RT and Middaugh CR, ed. New York, USA: Springer
    • Fardis M, Oliyai R. Case study: tenofovir disoproxil fumarate: an oral prodrug of tenofovir. In: Borchardt RT and Middaugh CR, ed. Prodrugs: Challenges and Rewards. New York, USA: Springer, 2008; 1347-57.
    • (2008) Prodrugs: Challenges and Rewards , pp. 1347-1357
    • Fardis, M.1    Oliyai, R.2
  • 12
    • 0031916651 scopus 로고    scopus 로고
    • Anti-human immunodeficiency virus activity and cellular metabolism of a potential prodrug of the acyclic nucleoside phosphonate 9-R-(2-phosphonomethoxypropyl) adenine (PMPA), bis(isopropyloxymethylcarbonyl)PMPA
    • Robbins BL, Srinivas RV, Kim C et al. Anti-human immunodeficiency virus activity and cellular metabolism of a potential prodrug of the acyclic nucleoside phosphonate 9-R-(2-phosphonomethoxypropyl) adenine (PMPA), bis(isopropyloxymethylcarbonyl)PMPA. Antimicrob Agents Chemother 1998; 42: 612-7.
    • (1998) Antimicrob Agents Chemother , vol.42 , pp. 612-617
    • Robbins, B.L.1    Srinivas, R.V.2    Kim, C.3
  • 13
    • 0031863214 scopus 로고    scopus 로고
    • Antiretroviral efficacy and pharmacokinetics of oral bis(isopropyloxycarbonyloxymethyl)9-(2-phosphonylmethoxypropyl)adenine in mice
    • Naesens L, Bischofberger N, Augustijns P et al. Antiretroviral efficacy and pharmacokinetics of oral bis(isopropyloxycarbonyloxymethyl)9-(2-phosphonylmethoxypropyl)adenine in mice. Antimicrob Agents Chemother 1998; 42: 1568-73.
    • (1998) Antimicrob Agents Chemother , vol.42 , pp. 1568-1573
    • Naesens, L.1    Bischofberger, N.2    Augustijns, P.3
  • 14
    • 34447265494 scopus 로고    scopus 로고
    • Molecular umbrellas: a novel class of candidate topical microbicides to prevent human immunodeficiency virus and herpes simplex virus infections
    • Madan RP, Mesquita PMM, Cheshenko N et al. Molecular umbrellas: a novel class of candidate topical microbicides to prevent human immunodeficiency virus and herpes simplex virus infections. J Virol 2007; 81: 7636-46.
    • (2007) J Virol , vol.81 , pp. 7636-7646
    • Madan, R.P.1    Mesquita, P.M.M.2    Cheshenko, N.3
  • 15
    • 45749114155 scopus 로고    scopus 로고
    • Candidate microbicide PPCM blocks human immunodeficiency virus type 1 infection in cell and tissue cultures and prevents genital herpes in a murine model
    • Mesquita PM, Wilson SS, Manlow P et al. Candidate microbicide PPCM blocks human immunodeficiency virus type 1 infection in cell and tissue cultures and prevents genital herpes in a murine model. J Virol 2008; 82: 6576-84.
    • (2008) J Virol , vol.82 , pp. 6576-6584
    • Mesquita, P.M.1    Wilson, S.S.2    Manlow, P.3
  • 16
    • 0014286962 scopus 로고
    • Characterization of herpes simplex virus strains differing in their effects on social behaviour of infected cells
    • Ejercito PM, Kieff ED, Roizman B. Characterization of herpes simplex virus strains differing in their effects on social behaviour of infected cells. J Gen Virol 1968; 2: 357-64.
    • (1968) J Gen Virol , vol.2 , pp. 357-364
    • Ejercito, P.M.1    Kieff, E.D.2    Roizman, B.3
  • 17
    • 54849431632 scopus 로고    scopus 로고
    • Polyurethane intravaginal ring for controlled delivery of dapivirine, a nonnucleoside reverse transcriptase inhibitor of HIV-1
    • Gupta KM, Pearce SM, Poursaid AE et al. Polyurethane intravaginal ring for controlled delivery of dapivirine, a nonnucleoside reverse transcriptase inhibitor of HIV-1. J Pharm Sci 2008; 97: 4228-39.
    • (2008) J Pharm Sci , vol.97 , pp. 4228-4239
    • Gupta, K.M.1    Pearce, S.M.2    Poursaid, A.E.3
  • 18
    • 84455200648 scopus 로고    scopus 로고
    • A hot-melt extruded intravaginal ring for the sustained delivery of the antiretroviral microbicide UC781
    • Clark MR, Johnson TJ, McCabe RT et al. A hot-melt extruded intravaginal ring for the sustained delivery of the antiretroviral microbicide UC781. J Pharm Sci 2012; 101: 576-87.
    • (2012) J Pharm Sci , vol.101 , pp. 576-587
    • Clark, M.R.1    Johnson, T.J.2    McCabe, R.T.3
  • 19
    • 0030732295 scopus 로고    scopus 로고
    • Sulfated carbohydrate compounds prevent microbial adherence by sexually transmitted disease pathogens
    • Herold BC, Siston A, Bremer J et al. Sulfated carbohydrate compounds prevent microbial adherence by sexually transmitted disease pathogens. Antimicrob Agents Chemother 1997; 41: 2776-80.
    • (1997) Antimicrob Agents Chemother , vol.41 , pp. 2776-2780
    • Herold, B.C.1    Siston, A.2    Bremer, J.3
  • 20
    • 0034034688 scopus 로고    scopus 로고
    • Parameters of human immunodeficiency virus infection of human cervical tissue and inhibition by vaginal virucides
    • Greenhead P, Hayes P, Watts PS et al. Parameters of human immunodeficiency virus infection of human cervical tissue and inhibition by vaginal virucides. J Virol 2000; 74: 5577-86.
    • (2000) J Virol , vol.74 , pp. 5577-5586
    • Greenhead, P.1    Hayes, P.2    Watts, P.S.3
  • 21
    • 69149100237 scopus 로고    scopus 로고
    • Disruption of tight junctions by cellulose sulfate facilitates HIV infection: model of microbicide safety
    • Mesquita PM, Cheshenko N, Wilson SS et al. Disruption of tight junctions by cellulose sulfate facilitates HIV infection: model of microbicide safety. J Infect Dis 2009; 200: 599-608.
    • (2009) J Infect Dis , vol.200 , pp. 599-608
    • Mesquita, P.M.1    Cheshenko, N.2    Wilson, S.S.3
  • 23
    • 0034949184 scopus 로고    scopus 로고
    • Degradation kinetics of oxycarbonyloxymethyl prodrugs of phosphonates in solution
    • Yuan LC, Dahl TC, Oliyai R. Degradation kinetics of oxycarbonyloxymethyl prodrugs of phosphonates in solution. Pharm Res 2001; 18: 234-7.
    • (2001) Pharm Res , vol.18 , pp. 234-237
    • Yuan, L.C.1    Dahl, T.C.2    Oliyai, R.3
  • 24
    • 0027422278 scopus 로고
    • Genotypic and phenotypic characterization of HIV-1 patients with primary infection
    • Zhu T, Mo H, Wang N et al. Genotypic and phenotypic characterization of HIV-1 patients with primary infection. Science 1993; 261: 1179-81.
    • (1993) Science , vol.261 , pp. 1179-1181
    • Zhu, T.1    Mo, H.2    Wang, N.3
  • 25
    • 33745842280 scopus 로고    scopus 로고
    • Ex vivo culture of human colorectal tissue for the evaluation of candidate microbicides
    • Fletcher PS, Elliott J, Grivel JC et al. Ex vivo culture of human colorectal tissue for the evaluation of candidate microbicides. AIDS 2006; 20: 1237-45.
    • (2006) AIDS , vol.20 , pp. 1237-1245
    • Fletcher, P.S.1    Elliott, J.2    Grivel, J.C.3
  • 26
    • 0346995096 scopus 로고    scopus 로고
    • Toxicity of nucleoside analogues used to treat AIDS and the selectivity of the mitochondrial DNA polymerase
    • Lee H, Hanes J, Johnson KA. Toxicity of nucleoside analogues used to treat AIDS and the selectivity of the mitochondrial DNA polymerase. Biochemistry 2003; 42: 14711-9.
    • (2003) Biochemistry , vol.42 , pp. 14711-14719
    • Lee, H.1    Hanes, J.2    Johnson, K.A.3
  • 27
    • 78650915162 scopus 로고    scopus 로고
    • No impact of oral tenofovir disoproxil fumarate on herpes simplex virus shedding in HIV-infected adults
    • Tan DH, Kaul R, Raboud JM et al. No impact of oral tenofovir disoproxil fumarate on herpes simplex virus shedding in HIV-infected adults. AIDS 2011; 25: 207-10.
    • (2011) AIDS , vol.25 , pp. 207-210
    • Tan, D.H.1    Kaul, R.2    Raboud, J.M.3
  • 28
    • 79960357319 scopus 로고    scopus 로고
    • MTN-001: a phase 2 cross-over study of daily oral and vaginal TFV in healthy, sexually active women results in significantly different product acceptability and vaginal tissue drug concentrations
    • Paper # 35LB. Foundation for Retrovirology and Human Health, Alexandria, VA, USA
    • Hendrix C, Minnis A, Guddera V et al. MTN-001: a phase 2 cross-over study of daily oral and vaginal TFV in healthy, sexually active women results in significantly different product acceptability and vaginal tissue drug concentrations. In: Abstracts of the Eighteenth Conference on Retroviruses and Opportunistic Infections, Boston, MA, 2011. Paper # 35LB. Foundation for Retrovirology and Human Health, Alexandria, VA, USA.
    • Abstracts of the Eighteenth Conference on Retroviruses and Opportunistic Infections, Boston, MA, 2011
    • Hendrix, C.1    Minnis, A.2    Guddera, V.3
  • 29
    • 79960372412 scopus 로고    scopus 로고
    • Drug concentrations after topical and oral antiretroviral pre-exposure prophylaxis: implications for HIV prevention in women
    • Karim SS, Kashuba AD, Werner L et al. Drug concentrations after topical and oral antiretroviral pre-exposure prophylaxis: implications for HIV prevention in women. Lancet 2011; 378: 279-81.
    • (2011) Lancet , vol.378 , pp. 279-281
    • Karim, S.S.1    Kashuba, A.D.2    Werner, L.3
  • 30
    • 68049121905 scopus 로고    scopus 로고
    • Safety and pharmacokinetics of dapivirine delivery from matrix and reservoir intravaginal rings to HIV-negative women
    • Nel A, Smythe S, Young K et al. Safety and pharmacokinetics of dapivirine delivery from matrix and reservoir intravaginal rings to HIV-negative women. J Acquir Immune Defic Syndr 2009; 51: 416-23.
    • (2009) J Acquir Immune Defic Syndr , vol.51 , pp. 416-423
    • Nel, A.1    Smythe, S.2    Young, K.3
  • 31
    • 25444524299 scopus 로고    scopus 로고
    • The combined contraceptive vaginal device (NuvaRing): a comprehensive review
    • Sarkar NN. The combined contraceptive vaginal device (NuvaRing): a comprehensive review. Eur J Contracept Reprod Health Care 2005; 10: 73-8.
    • (2005) Eur J Contracept Reprod Health Care , vol.10 , pp. 73-78
    • Sarkar, N.N.1
  • 32
    • 84858958650 scopus 로고    scopus 로고
    • Engineering a degradable polyurethane intravaginal ring for sustained delivery of dapivirine
    • Kaur M, Gupta K, Poursaid A et al. Engineering a degradable polyurethane intravaginal ring for sustained delivery of dapivirine. Drug Deliv Transl Res 2011; 1: 223-37.
    • (2011) Drug Deliv Transl Res , vol.1 , pp. 223-237
    • Kaur, M.1    Gupta, K.2    Poursaid, A.3
  • 34
    • 0035869104 scopus 로고    scopus 로고
    • Cervical ectopy in adolescent girls with and without human immunodeficiency virus infection
    • Moscicki AB, Ma Y, Holland C et al. Cervical ectopy in adolescent girls with and without human immunodeficiency virus infection. J Infect Dis 2001; 183: 865-70.
    • (2001) J Infect Dis , vol.183 , pp. 865-870
    • Moscicki, A.B.1    Ma, Y.2    Holland, C.3
  • 35
    • 84855833051 scopus 로고    scopus 로고
    • Vaginal Langerhans cells non-productively transporting HIV-1 mediate infection of T cells
    • Ballweber L, Robinson B, Kreger A et al. Vaginal Langerhans cells non-productively transporting HIV-1 mediate infection of T cells. J Virol 2011; 85: 13443-7.
    • (2011) J Virol , vol.85 , pp. 13443-13447
    • Ballweber, L.1    Robinson, B.2    Kreger, A.3
  • 36
    • 84455192446 scopus 로고    scopus 로고
    • The pharmacokinetics of tenofovir following intravaginal and intrarectal administration of tenofovir gel to rhesus macaques
    • Nuttall J, Kashuba A, Wang R et al. The pharmacokinetics of tenofovir following intravaginal and intrarectal administration of tenofovir gel to rhesus macaques. Antimicrob Agents Chemother 2012; 56: 103-9.
    • (2012) Antimicrob Agents Chemother , vol.56 , pp. 103-109
    • Nuttall, J.1    Kashuba, A.2    Wang, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.