Inter-individual variation in the effect of antiepileptic drugs in the intrahippocampal kainate model of mesial temporal lobe epilepsy in mice

Neuropharmacology

Volumn 90, Issue , 2015, Pages 53-62

  Klein, Sabine ^a,b   Bankstahl, Marion ^a,b   Löscher, Wolfgang ^a,b  

^a UNIVERSITY OF VETERINARY MEDICINE HANNOVER   (Germany)

^b CENTER FOR SYSTEMS NEUROSCIENCE   (Germany)

Author keywords

Anti seizure drugs; Hippocampus; Pharmacoresistance; Refractory seizures

Indexed keywords

ANTICONVULSIVE AGENT; CARBAMAZEPINE; DIAZEPAM; ETIRACETAM; KAINIC ACID; PHENOBARBITAL; PHENYTOIN; RETIGABINE; VALPROIC ACID; PIRACETAM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; DRUG MEGADOSE; DRUG RESPONSE; ELECTROGRAPHY; FEMALE; FOCAL EPILEPSY; MESIAL TEMPORAL LOBE EPILEPSY; MOUSE; MOUSE MODEL; NONHUMAN; SEIZURE; SINGLE DRUG DOSE; TONIC CLONIC SEIZURE; ANALOGS AND DERIVATIVES; ANIMAL; DISEASE MODEL; DRUG EFFECTS; DRUG RESISTANCE; ELECTRODE IMPLANT; ELECTROENCEPHALOGRAPHY; EPILEPSY, TEMPORAL LOBE; HIPPOCAMPUS; PATHOPHYSIOLOGY; PHYSIOLOGY; SEIZURES; VALIDATION STUDY;

ANIMALS; ANTICONVULSANTS; CARBAMAZEPINE; DIAZEPAM; DISEASE MODELS, ANIMAL; DRUG RESISTANCE; ELECTRODES, IMPLANTED; ELECTROENCEPHALOGRAPHY; EPILEPSY, TEMPORAL LOBE; FEMALE; HIPPOCAMPUS; KAINIC ACID; MICE; PHENOBARBITAL; PHENYTOIN; PIRACETAM; SEIZURES; VALPROIC ACID;

EID: 84915818802     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2014.11.008     Document Type: Article

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