A novel dopamine D3 receptor antagonist YQA14 inhibits methamphetamine self-administration and relapse to drug-seeking behaviour in rats

European Journal of Pharmacology

Volumn 743, Issue , 2014, Pages 126-132

  Chen, Ying ^a   Song, Rui ^a   Yang, Ri Fang ^a   Wu, Ning ^a   Li, Jin ^a  

^a BEIJING INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY   (China)

Author keywords

Dopamine D3 receptor; Drug reward; Methamphetamine (METH); Relapse; Self administration; YQA14

Indexed keywords

DOPAMINE 3 RECEPTOR BLOCKING AGENT; METHAMPHETAMINE; UNCLASSIFIED DRUG; YQA 14; BENZOXAZOLE DERIVATIVE; COCAINE; DOPAMINE 3 RECEPTOR; DOPAMINE RECEPTOR BLOCKING AGENT; PIPERAZINE DERIVATIVE; YQA14;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASSOCIATION; ATTENUATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG EFFECT; DRUG SEEKING BEHAVIOR; DRUG SELF ADMINISTRATION; MALE; NONHUMAN; RAT; REINFORCEMENT; RELAPSE; REWARD; SYSTEMIC THERAPY; ANIMAL; ANIMAL BEHAVIOR; ANTAGONISTS AND INHIBITORS; COCAINE-RELATED DISORDERS; DRUG EFFECTS; PROCEDURES; RECURRENT DISEASE; SPRAGUE DAWLEY RAT;

ANIMALS; BEHAVIOR, ANIMAL; BENZOXAZOLES; COCAINE; COCAINE-RELATED DISORDERS; DOPAMINE ANTAGONISTS; DRUG-SEEKING BEHAVIOR; EXTINCTION, PSYCHOLOGICAL; MALE; METHAMPHETAMINE; PIPERAZINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, DOPAMINE D3; RECURRENCE; REINFORCEMENT (PSYCHOLOGY); SELF ADMINISTRATION;

EID: 84915817233     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2014.09.026     Document Type: Article

References (47)

1. H. Aujla, and R.J. Beninger The dopamine D(3) receptor-preferring partial agonist BP 897 dose-dependently attenuates the expression of amphetamine-conditioned place preference in rats Behav. Pharmacol. 16 2005 181 186
2. A.M. Barr, W.J. Panenka, G.W. MacEwan, A.E. Thornton, D.J. Lang, W.G. Honer, and T. Lecomte The need for speed: an update on methamphetamine addiction J. Neurol. Neurosurg. Psychiatry 31 2006 301 313
3. 3 receptor-preferring ligand [11C]-(+)-propyl-hexahydro-naphtho-oxazin in methamphetamine polydrug users: a positron emission tomography study J. Neurosci. 32 2012 1353 1359
4. J.M. Bossert, N.J. Marchant, D.J. Calu, and Y. Shaham The reinstatement model of drug relapse: recent neurobiological findings, emerging research topics, and translational research Psychopharmacology 229 2013 453 476
5. M.S. Castaneto, A.J. Barnes, K.B. Scheidweiler, M. Schaffer, K.K. Rogers, D. Stewart, and M.A. Huestis Identifying methamphetamine exposure in children Ther. Drug Monit. 35 2013 823 830
6. 2 dopamine receptors Neuropsychopharmacology 28 2003 1150 1159
7. China Monitoring Center for Drugs and Drug Abuse, 2013. Annual report 2012: The state of the drug problem in China, 2012. Available at 〈http://www.gov.cn/gzdt/2013-10/17/content-2509156.htm〉
8. K.L. Conrad, K. Ford, M. Marinelli, and M.E. Wolf Dopamine receptor expression and distribution dynamically change in the rat nucleus accumbens after withdrawal from cocaine self-administration Neuroscience 169 2010 182 194
9. H.S. Crombag, J.M. Bossert, E. Koya, and Y. Shaham Review. Context-induced relapse to drug seeking: a review Philos. Trans. R. Soc. B 363 2008 3233 3243
10. E.L. Gardner What we have learned about addiction from animal models of drug self-administration Am. J. Addict. 9 2000 285 313
11. 3 receptors as a target for drug addiction pharmacotherapy: a review of preclinical evidence CNS Neurol. Disord. Drug Targets 7 2008 410 421
12. 3 receptors in drug addiction: a review of pharmacological evidence Brain Res. Rev. 49 2005 77 105
13. C.A. Heidbreder, and A.H. Newman Current perspectives on selective dopamine D(3) receptor antagonists as pharmacotherapeutics for addictions and related disorders Ann. N. Y. Acad. Sci. 1187 2010 4 34
14. A.E. Higley, S.W. Kiefer, X. Li, J. Gaal, Z.X. Xi, and E.L. Gardner Dopamine D(3) receptor antagonist SB-277011A inhibits methamphetamine self-administration and methamphetamine-induced reinstatement of drug-seeking in rats Eur. J. Pharmacol. 659 2011 187 192
15. 3 receptor antagonist, inhibits the effects of methamphetamine in rats J. Psychopharmacol. 25 2011 263 273
16. R. Hu, R. Song, R. Yang, R. Su, and J. Li The dopamine D receptor antagonist YQA14 that inhibits the expression and drug-primed reactivation of morphine-induced conditioned place preference in rats Eur. J. Pharmacol. 720 2013 212 217
17. J.H. Jaffe, N.G. Cascella, K.M. Kumor, and M.A. Sherer Cocaine-induced cocaine craving Psychopharmacology 97 1989 59 64
18. P.W. Kalivas, and K. McFarland Brain circuitry and the reinstatement of cocaine-seeking behavior Psychopharmacology 168 2003 44 56
19. L. Karila, A. Weinstein, H.J. Aubin, A. Benyamina, M. Reynaud, and S.L. Batki Pharmacological approaches to methamphetamine dependence: a focused review Br. J. Clin. Pharmacol. 69 2010 578 592
20. 3 receptor and drug dependence: effects on reward or beyond? Neuropharmacology 49 2005 525 541
21. 3 receptor ligands for drug addiction treatment: update on recent findings Prog. Brain Res. 211 2014 255 275
22. 3 receptor is necessary for ethanol consumption: an approach with buspirone Neuropsychopharmacology 39 2014 2017 2028
23. F. Liu, X. Zhuang, C. Yang, Z. Li, S. Xiong, Z. Zhang, J. Li, and C. Lu Characterization of preclinical in vitro and in vivo ADME properties and prediction of human PK using a physiologically based pharmacokinetic model for YQA-14, a new dopamine D receptor antagonist candidate for treatment of drug addiction Biopharm. Drug Dispos. 35 2014 296 307
24. S. Liu, F. Zhu, M. Lai, L. Sun, Y. Liu, and W. Zhou Electroacupuncture suppresses discrete cue-evoked heroin-seeking and fos protein expression in the nucleus accumbens core in rats Evid.-Based Complement. Altern. Med.: eCAM 2012 2012 286404
25. 3 receptor antagonist J. Med. Chem. 46 2003 4952 4964
26. J.C. Maxwell Emerging research on methamphetamine Curr. Opin. Psychiatry 18 2005 235 242
27. 3 receptor binding in rats receiving a cocaine challenge at various time points after cocaine self-administration: implications for cocaine-seeking behavior Neuropsychopharmacology 29 2004 1479 1487
28. 3 receptor partial agonists and antagonists as potential drug abuse therapeutic agents J. Med. Chem. 48 2005 3663 3679
29. C.P. O'Brien, A.R. Childress, A.T. McLellan, and R. Ehrman Classical conditioning in drug-dependent humans Ann. N. Y. Acad. Sci. 654 1992 400 415
30. C.P. O'Brien, and E.L. Gardner Critical assessment of how to study addiction and its treatment: human and non-human animal models Pharmacol. Ther. 108 2005 18 58
31. N.R. Richardson, and D.C. Roberts Progressive ratio schedules in drug self-administration studies in rats: a method to evaluate reinforcing efficacy J. Neurosci. Methods 66 1996 1 11
32. Y. Shaham, and J. Stewart Exposure to mild stress enhances the reinforcing efficacy of intravenous heroin self-administration in rats Psychopharmacology 114 1994 523 527
33. U. Shalev, J.W. Grimm, and Y. Shaham Neurobiology of relapse to heroin and cocaine seeking: a review Pharmacol. Rev. 54 2002 1 42
34. U. Shalev, D. Highfield, J. Yap, and Y. Shaham Stress and relapse to drug seeking in rats: studies on the generality of the effect Psychopharmacology 150 2000 337 346
35. R. Sinha How does stress increase risk of drug abuse and relapse? Psychopharmacology 158 2001 343 359
36. P. Sokoloff, B. Giros, M.P. Martres, M.L. Bouthenet, and J.C. Schwartz Molecular cloning and characterization of a novel dopamine receptor (D3) as a target for neuroleptics Nature 347 1990 146 151
37. 3 receptors by YQA14 inhibits cocaine's rewarding effects and relapse to drug-seeking behavior in rats Neuropharmacology 77 2014 398 405
38. 3 receptor-knockout mice Addict. Biol. 17 2012 259 273
39. 3 receptors Proc. Natl. Acad. Sci. USA 109 2012 17675 17680
40. R. Song, H.Y. Zhang, X.Q. Peng, R.B. Su, R.F. Yang, J. Li, Z.X. Xi, and E.L. Gardner Dopamine D(3) receptor deletion or blockade attenuates cocaine-induced conditioned place preference in mice Neuropharmacology 72 2013 82 87
41. 3 receptor agonist BP-897 attenuate methamphetamine-enhanced brain stimulation reward in rats Psychopharmacology 196 2008 533 542
42. 3 dopamine receptors in the brain reward circuits of human cocaine fatalities J. Neurosci. 16 1996 6100 6106
43. J.D. Steketee, and P.W. Kalivas Drug wanting: behavioral sensitization and relapse to drug-seeking behavior Pharmacol. Rev. 63 2011 348 365
44. J. Stewart Pathways to relapse: the neurobiology of drug- and stress-induced relapse to drug-taking J. Psychiatry Neurosci. 25 2000 125 136
45. F.J. Vocci, and N.M. Appel Approaches to the development of medications for the treatment of methamphetamine dependence Addiction 102 Suppl. 1 2007 S96 S106
46. Z.X. Xi, and E.L. Gardner Pharmacological actions of NGB 2904, a selective dopamine D3 receptor antagonist, in animal models of drug addiction CNS Drug Rev. 13 2007 240 259
47. Z.X. Xi, and E.L. Gardner Hypothesis-driven medication discovery for the treatment of psychostimulant addiction Curr. Drug Abus. Rev. 1 2008 303 327