Apo, Zn2+ -bound and Mn2+ -bound structures reveal ligand-binding properties of SitA from the pathogen Staphylococcus pseudintermedius

Bioscience Reports

Volumn 34, Issue 6, 2014, Pages 743-758

  Abate, Francesca ^a,b   Malito, Enrico ^a   Cozzi, Roberta ^a   Lo Surdo, Paola ^a   Maione, Domenico ^a   Bottomley, Matthew J ^a  

^a NOVARTIS VACCINES AND DIAGNOSTICS   (Italy)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Class III solute binding protein; Divalent metal cation; Manganese; Staphylococcal disease; Transport; Zinc

Indexed keywords

ABC TRANSPORTER; APOPROTEIN; LIPOPROTEIN; MAGNESIUM ION; SITA PROTEIN; UNCLASSIFIED DRUG; ZINC ION; APOLIPOPROTEIN; BACTERIAL PROTEIN; MANGANESE; PROTEIN BINDING; ZINC;

ARTICLE; BINDING SITE; CHANNEL GATING; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; LIGAND BINDING; METAL BINDING; NONHUMAN; NUCLEOTIDE SEQUENCE; POINT MUTATION; PROTEIN STABILITY; PROTEIN STRUCTURE; SITE DIRECTED MUTAGENESIS; STAPHYLOCOCCUS PSEUDINTERMEDIUS; AMINO ACID SEQUENCE; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; CIRCULAR DICHROISM; DIFFERENTIAL SCANNING CALORIMETRY; DOG; DOG DISEASE; GENETICS; HUMAN; METABOLISM; MICROBIOLOGY; MISSENSE MUTATION; MOLECULAR GENETICS; PHYSIOLOGY; PROTEIN MULTIMERIZATION; PROTEIN QUATERNARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; SEQUENCE HOMOLOGY; STAPHYLOCOCCUS; STAPHYLOCOCCUS INFECTION; X RAY CRYSTALLOGRAPHY;

STAPHYLOCOCCUS PSEUDINTERMEDIUS;

AMINO ACID SEQUENCE; ANIMALS; APOLIPOPROTEINS; BACTERIAL PROTEINS; CALORIMETRY, DIFFERENTIAL SCANNING; CIRCULAR DICHROISM; CRYSTALLOGRAPHY, X-RAY; DOG DISEASES; DOGS; HUMANS; MANGANESE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION, MISSENSE; PROTEIN BINDING; PROTEIN MULTIMERIZATION; PROTEIN STABILITY; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; SEQUENCE HOMOLOGY, AMINO ACID; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS; ZINC;

EID: 84915816813     PISSN: 01448463     EISSN: 15734935     Source Type: Journal    
DOI: 10.1042/BSR20140088     Document Type: Article

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