메뉴 건너뛰기




Volumn 45, Issue 7, 2014, Pages 589-595

Oral Coenzyme Q10 Supplementation in Patients with Nonalcoholic Fatty Liver Disease: Effects on Serum Vaspin, Chemerin, Pentraxin 3, Insulin Resistance and Oxidative Stress

Author keywords

Coenzyme Q10; Insulin resistance; Nonalcoholic fatty liver disease (NAFLD); Oxidative stress

Indexed keywords

ADIPOCYTOKINE; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CHEMERIN; GLUCOSE; MALONALDEHYDE; PENTRAXIN 3; PLACEBO; UBIDECARENONE; VASPIN; ANTIOXIDANT; BIOLOGICAL MARKER; C REACTIVE PROTEIN; CHEMERIN, HUMAN; CHEMOKINE; GLUCOSE BLOOD LEVEL; SERINE PROTEINASE INHIBITOR; SERPINA12 PROTEIN, HUMAN; SERUM AMYLOID P; UBIQUINONE;

EID: 84915803580     PISSN: 01884409     EISSN: 18735487     Source Type: Journal    
DOI: 10.1016/j.arcmed.2014.11.001     Document Type: Article
Times cited : (83)

References (45)
  • 1
    • 66349125337 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease
    • Erickson S.K. Nonalcoholic fatty liver disease. J Lipid Res 2009, 50(suppl):412-416.
    • (2009) J Lipid Res , vol.50 , pp. 412-416
    • Erickson, S.K.1
  • 2
    • 84915807631 scopus 로고    scopus 로고
    • Chemerin in non-alcoholic fatty liver disease? Up or down?
    • Buechler C. Chemerin in non-alcoholic fatty liver disease? Up or down?. Endocrinol Metab Syndr 2013, 2:1-3.
    • (2013) Endocrinol Metab Syndr , vol.2 , pp. 1-3
    • Buechler, C.1
  • 3
    • 33644547706 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: from steatosis to cirrhosis
    • Farrell G.C., Larter C.Z. Nonalcoholic fatty liver disease: from steatosis to cirrhosis. Hepatology 2006, 43(suppl):99-112.
    • (2006) Hepatology , vol.43 , pp. 99-112
    • Farrell, G.C.1    Larter, C.Z.2
  • 4
    • 10644220306 scopus 로고    scopus 로고
    • Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity
    • Browning J.D., Szczepaniak L.S., Dobbins R. Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity. Hepatology 2004, 40:1387-1395.
    • (2004) Hepatology , vol.40 , pp. 1387-1395
    • Browning, J.D.1    Szczepaniak, L.S.2    Dobbins, R.3
  • 5
    • 22344452893 scopus 로고    scopus 로고
    • The natural history of non-alcoholic fatty liver disease: a population-based cohort study
    • Adams L.A., Lymp J.F., St Sauver J. The natural history of non-alcoholic fatty liver disease: a population-based cohort study. Gastroenterology 2005, 129:113-121.
    • (2005) Gastroenterology , vol.129 , pp. 113-121
    • Adams, L.A.1    Lymp, J.F.2    St Sauver, J.3
  • 6
    • 78650774076 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver in Asia: firmly entrenched and rapidly gaining ground
    • Chitturi S., Wong V.W., Farrell G., et al. Nonalcoholic fatty liver in Asia: firmly entrenched and rapidly gaining ground. J Gastroenterol Hepatol 2011, 26(suppl):163-172.
    • (2011) J Gastroenterol Hepatol , vol.26 , pp. 163-172
    • Chitturi, S.1    Wong, V.W.2    Farrell, G.3
  • 7
    • 38349107613 scopus 로고    scopus 로고
    • Adipokines and cytokines in non-alcoholic fatty liver disease
    • Jarrar M.H., Baranova A., Collantes R., et al. Adipokines and cytokines in non-alcoholic fatty liver disease. Aliment Pharmacol Ther 2008, 27:412-421.
    • (2008) Aliment Pharmacol Ther , vol.27 , pp. 412-421
    • Jarrar, M.H.1    Baranova, A.2    Collantes, R.3
  • 8
    • 84882741140 scopus 로고    scopus 로고
    • Chemerin is highly expressed in hepatocytes and is induced in non-alcoholic steatohepatitis liver
    • Krautbauer S., Wanninger J., Eisinger K., et al. Chemerin is highly expressed in hepatocytes and is induced in non-alcoholic steatohepatitis liver. Exp Mol Pathol 2013, 95:199-205.
    • (2013) Exp Mol Pathol , vol.95 , pp. 199-205
    • Krautbauer, S.1    Wanninger, J.2    Eisinger, K.3
  • 9
    • 53349120340 scopus 로고    scopus 로고
    • Chemerin reveals its chimeric nature
    • Yoshimura T., Oppenheim J.J. Chemerin reveals its chimeric nature. J Exp Med 2008, 205:2187-2190.
    • (2008) J Exp Med , vol.205 , pp. 2187-2190
    • Yoshimura, T.1    Oppenheim, J.J.2
  • 10
    • 34548572409 scopus 로고    scopus 로고
    • Chemerin: a new adipokine that modulates adipogenesis via its own receptor
    • Roh S.G., Song S.H., Choi K.C., et al. Chemerin: a new adipokine that modulates adipogenesis via its own receptor. Biochem Biophys Res Commun 2007, 362:1013-1018.
    • (2007) Biochem Biophys Res Commun , vol.362 , pp. 1013-1018
    • Roh, S.G.1    Song, S.H.2    Choi, K.C.3
  • 11
    • 39649114784 scopus 로고    scopus 로고
    • Chemerin enhances insulin signaling and potentiates insulin-stimulated glucose uptake in 3T3-L1 adipocytes
    • Takahashi M., Takahashi Y., Takahashi K., et al. Chemerin enhances insulin signaling and potentiates insulin-stimulated glucose uptake in 3T3-L1 adipocytes. FEBS Lett 2008, 582:573-578.
    • (2008) FEBS Lett , vol.582 , pp. 573-578
    • Takahashi, M.1    Takahashi, Y.2    Takahashi, K.3
  • 12
    • 84885159392 scopus 로고    scopus 로고
    • Elevated hepatic chemerin mRNA expression in human non-alcoholic fatty liver disease
    • Docke S., Lock J.F., Birkenfeld A.L., et al. Elevated hepatic chemerin mRNA expression in human non-alcoholic fatty liver disease. Eur J Endocrinol 2013, 169:547-557.
    • (2013) Eur J Endocrinol , vol.169 , pp. 547-557
    • Docke, S.1    Lock, J.F.2    Birkenfeld, A.L.3
  • 13
    • 79952988824 scopus 로고    scopus 로고
    • Serum levels of vaspin, obestatin, and apelin-36 in patients with nonalcoholic fatty liver disease
    • Aktas B., Yilmaz Y., Eren F., et al. Serum levels of vaspin, obestatin, and apelin-36 in patients with nonalcoholic fatty liver disease. Metabolism 2011, 60:544-549.
    • (2011) Metabolism , vol.60 , pp. 544-549
    • Aktas, B.1    Yilmaz, Y.2    Eren, F.3
  • 14
    • 79960212414 scopus 로고    scopus 로고
    • Circulating vaspin levels and epicardial adipose tissue thickness are associated with impaired coronary flow reserve in patients with nonalcoholic fatty liver disease
    • Yilmaz Y., Kurt R., Gurdal A., et al. Circulating vaspin levels and epicardial adipose tissue thickness are associated with impaired coronary flow reserve in patients with nonalcoholic fatty liver disease. Atherosclerosis 2008, 217:125-129.
    • (2008) Atherosclerosis , vol.217 , pp. 125-129
    • Yilmaz, Y.1    Kurt, R.2    Gurdal, A.3
  • 15
    • 76749098030 scopus 로고    scopus 로고
    • Serum chemerin and vaspin in non-alcoholic fatty liver disease
    • Kukla M., Zwirska-Korczala K., Hartleb M., et al. Serum chemerin and vaspin in non-alcoholic fatty liver disease. Scand J Gastroenterol 2010, 45:235-242.
    • (2010) Scand J Gastroenterol , vol.45 , pp. 235-242
    • Kukla, M.1    Zwirska-Korczala, K.2    Hartleb, M.3
  • 16
    • 0035667921 scopus 로고    scopus 로고
    • Biochemical functions of coenzyme Q10
    • Crane F.L. Biochemical functions of coenzyme Q10. J Am Coll Nutr 2001, 20:591-598.
    • (2001) J Am Coll Nutr , vol.20 , pp. 591-598
    • Crane, F.L.1
  • 17
    • 70349767934 scopus 로고    scopus 로고
    • Coenzyme Q10 supplementation lowers hepatic oxidative stress and inflammation associated with diet-induced obesity in mice
    • Sohet F.M., Neyrinck A.M., Pachikian B.D., et al. Coenzyme Q10 supplementation lowers hepatic oxidative stress and inflammation associated with diet-induced obesity in mice. Biochem Pharmacol 2009, 78:1391-1400.
    • (2009) Biochem Pharmacol , vol.78 , pp. 1391-1400
    • Sohet, F.M.1    Neyrinck, A.M.2    Pachikian, B.D.3
  • 18
    • 60249097822 scopus 로고    scopus 로고
    • Coadministration of coenzyme Q prevents rosiglitazone-induced adipogenesis in ob/ob mice
    • Carmona M.C., Lefebvre P., Lefebvre B., et al. Coadministration of coenzyme Q prevents rosiglitazone-induced adipogenesis in ob/ob mice. Int J Obes 2009, 33:204-211.
    • (2009) Int J Obes , vol.33 , pp. 204-211
    • Carmona, M.C.1    Lefebvre, P.2    Lefebvre, B.3
  • 19
    • 58149387518 scopus 로고    scopus 로고
    • Functions of coenzyme Q10 in inflammation and gene expression
    • Schmelzer C., Lindner I., Rimbach G., et al. Functions of coenzyme Q10 in inflammation and gene expression. Biofactors 2008, 32:179-183.
    • (2008) Biofactors , vol.32 , pp. 179-183
    • Schmelzer, C.1    Lindner, I.2    Rimbach, G.3
  • 20
    • 84915754886 scopus 로고    scopus 로고
    • Role of coenzyme Q10, metformin and rosiglitazone in treatment of experimental nonalcoholic steatohepatitis in rats
    • El-Hamid M.A., El-Halim M.S., Karima I., et al. Role of coenzyme Q10, metformin and rosiglitazone in treatment of experimental nonalcoholic steatohepatitis in rats. Tanta Med Sc J 2008, 3:15-29.
    • (2008) Tanta Med Sc J , vol.3 , pp. 15-29
    • El-Hamid, M.A.1    El-Halim, M.S.2    Karima, I.3
  • 21
    • 84857676919 scopus 로고    scopus 로고
    • Coenzyme Q metabolism is disturbed in high fat diet-induced nonalcoholic fatty liver disease in rats
    • Bravo E., Palleschi S., Rossi B., et al. Coenzyme Q metabolism is disturbed in high fat diet-induced nonalcoholic fatty liver disease in rats. Int J Mol Sci 2012, 13:1644-1657.
    • (2012) Int J Mol Sci , vol.13 , pp. 1644-1657
    • Bravo, E.1    Palleschi, S.2    Rossi, B.3
  • 22
    • 33645854921 scopus 로고    scopus 로고
    • Safety assessment of coenzyme Q10 in healthy subjects: a double-blind, randomized, placebo-controlled trial
    • Ikematsu H., Nakamura K., Harashima S., et al. Safety assessment of coenzyme Q10 in healthy subjects: a double-blind, randomized, placebo-controlled trial. Regul Toxicol Pharmacol 2006, 44:212-218.
    • (2006) Regul Toxicol Pharmacol , vol.44 , pp. 212-218
    • Ikematsu, H.1    Nakamura, K.2    Harashima, S.3
  • 25
    • 84873693062 scopus 로고    scopus 로고
    • Report of a WHO expert consultation, Geneva: 8-11 December2008.
    • World Health Organization (WHO). Waist circumference and waist-hip ratio. Report of a WHO expert consultation, Geneva: 8-11 December2008.
    • Waist circumference and waist-hip ratio
  • 26
    • 84915777117 scopus 로고    scopus 로고
    • guidelines for data processing and analysis of the international physical activity questionnaire. November 2005. Available from: .
    • International Physical Activity Questionnaire (IPAQ) guidelines for data processing and analysis of the international physical activity questionnaire. November 2005. Available from: . http://www.ipaq.ki.se/scoring.pdf.
  • 27
    • 0036829092 scopus 로고    scopus 로고
    • AGA technical review on nonalcoholic fatty liver disease
    • Sanyal A.J. AGA technical review on nonalcoholic fatty liver disease. Gastroenterology 2002, 123:1705-1725.
    • (2002) Gastroenterology , vol.123 , pp. 1705-1725
    • Sanyal, A.J.1
  • 28
    • 0021813187 scopus 로고
    • Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man
    • Matthews D.R., Hosker J.P., Rudenski A.S., et al. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985, 28:412-419.
    • (1985) Diabetologia , vol.28 , pp. 412-419
    • Matthews, D.R.1    Hosker, J.P.2    Rudenski, A.S.3
  • 29
    • 11144235336 scopus 로고    scopus 로고
    • Prevalence of the insulin resistance syndrome in obesity
    • Viner R.M., Segal T.Y., Lichtarowicz-Krynska E., et al. Prevalence of the insulin resistance syndrome in obesity. Arch Dis Child 2005, 90:10-14.
    • (2005) Arch Dis Child , vol.90 , pp. 10-14
    • Viner, R.M.1    Segal, T.Y.2    Lichtarowicz-Krynska, E.3
  • 30
    • 0018069570 scopus 로고
    • Determination of malonaldehyde precursor in tissues by thiobarbituric acid test
    • Mihara M., Uchiyama M. Determination of malonaldehyde precursor in tissues by thiobarbituric acid test. Anal Biochem 1978, 86:271-278.
    • (1978) Anal Biochem , vol.86 , pp. 271-278
    • Mihara, M.1    Uchiyama, M.2
  • 31
    • 84892701455 scopus 로고    scopus 로고
    • Coenzyme Q10 supplementation improves metabolic parameters, liver function and mitochondrial respiration in rats with high doses of atorvastatin and a cholesterol-rich diet
    • Jimenez-Santos M.A., Juarez-Rojop I.E., Tovilla-Zarate C.A., et al. Coenzyme Q10 supplementation improves metabolic parameters, liver function and mitochondrial respiration in rats with high doses of atorvastatin and a cholesterol-rich diet. Lipids Health Dis 2014, 13:22-32.
    • (2014) Lipids Health Dis , vol.13 , pp. 22-32
    • Jimenez-Santos, M.A.1    Juarez-Rojop, I.E.2    Tovilla-Zarate, C.A.3
  • 32
    • 0036827017 scopus 로고    scopus 로고
    • Coenzyme Q10 improves blood pressure and glycaemic control: a controlled trial in subjects with type 2 diabetes
    • Hodgson J.M., Watts G.F., Playford D.A., et al. Coenzyme Q10 improves blood pressure and glycaemic control: a controlled trial in subjects with type 2 diabetes. Eur J Clin Nutr 2002, 56:1137-1142.
    • (2002) Eur J Clin Nutr , vol.56 , pp. 1137-1142
    • Hodgson, J.M.1    Watts, G.F.2    Playford, D.A.3
  • 34
    • 84883689450 scopus 로고    scopus 로고
    • The effect of co-enzyme Q10 on acute liver damage in rats: a biochemical and pathological study
    • Esfahani S.A., Esmaeilzadeh E., Bagheri F., et al. The effect of co-enzyme Q10 on acute liver damage in rats: a biochemical and pathological study. Hepat Mon 2013, 13:e13658.
    • (2013) Hepat Mon , vol.13 , pp. e13658
    • Esfahani, S.A.1    Esmaeilzadeh, E.2    Bagheri, F.3
  • 35
    • 84856482639 scopus 로고    scopus 로고
    • Coenzyme Q10 supplementation reduces oxidative stress and increases antioxidant enzyme activity in patients with coronary artery disease
    • Lee B.J., Huang Y.C., Chen S.J., et al. Coenzyme Q10 supplementation reduces oxidative stress and increases antioxidant enzyme activity in patients with coronary artery disease. Nutrition 2012, 28:250-255.
    • (2012) Nutrition , vol.28 , pp. 250-255
    • Lee, B.J.1    Huang, Y.C.2    Chen, S.J.3
  • 36
    • 77954176232 scopus 로고    scopus 로고
    • Coenzyme Q10 supplementation decreases oxidative stress and improves physical performance in young swimmers: a pilot study
    • Leelarungrayub D., Sawattikanon N., Klaphajone J., et al. Coenzyme Q10 supplementation decreases oxidative stress and improves physical performance in young swimmers: a pilot study. Open Sports Med J 2010, 4:1-8.
    • (2010) Open Sports Med J , vol.4 , pp. 1-8
    • Leelarungrayub, D.1    Sawattikanon, N.2    Klaphajone, J.3
  • 37
    • 84915737491 scopus 로고    scopus 로고
    • Effect of short-term coenzyme Q10 supplementation on oxidative stress index and total antioxidant capacity of serum in inactive men
    • Rostami A., Jafari A. Effect of short-term coenzyme Q10 supplementation on oxidative stress index and total antioxidant capacity of serum in inactive men. Med J Tabriz Univ Med Sci 2012, 34:46-51.
    • (2012) Med J Tabriz Univ Med Sci , vol.34 , pp. 46-51
    • Rostami, A.1    Jafari, A.2
  • 38
    • 45149115006 scopus 로고    scopus 로고
    • Effects of acute and 14-day coenzyme Q10 supplementation on exercise performance in both trained and untrained individuals
    • Cooke M., Iosia M., Buford T., et al. Effects of acute and 14-day coenzyme Q10 supplementation on exercise performance in both trained and untrained individuals. J Int Soc Sports Nutr 2008, 5:1-14.
    • (2008) J Int Soc Sports Nutr , vol.5 , pp. 1-14
    • Cooke, M.1    Iosia, M.2    Buford, T.3
  • 39
    • 79953211125 scopus 로고    scopus 로고
    • 10 on arterial stiffness, metabolic parameters, and fatigue in obese subjects: a double-blind randomized controlled study
    • 10 on arterial stiffness, metabolic parameters, and fatigue in obese subjects: a double-blind randomized controlled study. J Med Food 2011, 14:386-390.
    • (2011) J Med Food , vol.14 , pp. 386-390
    • Lee, Y.J.1    Cho, W.J.2    Kim, J.K.3
  • 40
    • 84915754915 scopus 로고    scopus 로고
    • The coenzyme Q10 supplementation effects on lipid profile, fasting blood sugar, blood pressure and oxidative stress status among non-alcoholic fatty liver disease patients: a randomized, placebo-controlled, pilot study
    • Mohammadshahi M., Farsi F., Alavi-Nejad P., et al. The coenzyme Q10 supplementation effects on lipid profile, fasting blood sugar, blood pressure and oxidative stress status among non-alcoholic fatty liver disease patients: a randomized, placebo-controlled, pilot study. J Gastroentrol Hepatic Res 2014, 3:1103-1108.
    • (2014) J Gastroentrol Hepatic Res , vol.3 , pp. 1103-1108
    • Mohammadshahi, M.1    Farsi, F.2    Alavi-Nejad, P.3
  • 41
    • 40949151070 scopus 로고    scopus 로고
    • Vaspin: a new serpin with insulin sensitizing effects
    • Wada J. Vaspin: a new serpin with insulin sensitizing effects. Expert Opin Investig Drugs 2008, 17:327-333.
    • (2008) Expert Opin Investig Drugs , vol.17 , pp. 327-333
    • Wada, J.1
  • 42
    • 73449085869 scopus 로고    scopus 로고
    • Serum vaspin level in relation to postprandial plasma glucose concentration in subjects with diabetes
    • Yin Y., Xu-hong H., Xiao-ping P., et al. Serum vaspin level in relation to postprandial plasma glucose concentration in subjects with diabetes. Chin Med J 2009, 122:2530-2533.
    • (2009) Chin Med J , vol.122 , pp. 2530-2533
    • Yin, Y.1    Xu-hong, H.2    Xiao-ping, P.3
  • 43
    • 48249120025 scopus 로고    scopus 로고
    • Metformin decreases the adipokine vaspin in overweight women with polycystic ovary syndrome concomitant with improvement in insulin sensitivity and a decrease in insulin resistance
    • Tan B.K., Heutling D., Chen J., et al. Metformin decreases the adipokine vaspin in overweight women with polycystic ovary syndrome concomitant with improvement in insulin sensitivity and a decrease in insulin resistance. Diabetes 2008, 57:1501-1507.
    • (2008) Diabetes , vol.57 , pp. 1501-1507
    • Tan, B.K.1    Heutling, D.2    Chen, J.3
  • 44
    • 0034622540 scopus 로고    scopus 로고
    • PTX3, a prototypical long pentraxin, is an early indicator of acute myocardial infarction in humans
    • Peri G., Introna M., Corradi D., et al. PTX3, a prototypical long pentraxin, is an early indicator of acute myocardial infarction in humans. Circulation 2000, 102:636-641.
    • (2000) Circulation , vol.102 , pp. 636-641
    • Peri, G.1    Introna, M.2    Corradi, D.3
  • 45
    • 70349786070 scopus 로고    scopus 로고
    • Circulating pentraxin 3 levels are higher in metabolic syndrome with subclinical atherosclerosis: evidence for association with atherogenic lipid profile
    • Zanetti M., Bosutti A., Ferreira C., et al. Circulating pentraxin 3 levels are higher in metabolic syndrome with subclinical atherosclerosis: evidence for association with atherogenic lipid profile. Clin Exp Med 2009, 9:243-248.
    • (2009) Clin Exp Med , vol.9 , pp. 243-248
    • Zanetti, M.1    Bosutti, A.2    Ferreira, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.