A crucial role for the phosphorylation of STRAP at Ser188 by MPK38 in STRAP-dependent cell death through ASK1, TGF-β, p53, and PI3K/PDK1 signaling pathways

Cell Cycle

Volumn 13, Issue 21, 2014, Pages 3357-3374

  Seong, Hyun A ^a   Manoharan, Ravi ^a   Ha, Hyunjung ^a  

^a Chungbuk National University   (South Korea)

Author keywords

ASK1; MPK38 MELK; P53; PI3K PDK1; STRAP; TGF

Indexed keywords

1 CHLORO 2,4 DINITROBENZENE; ALANINE AMINOTRANSFERASE; APOPTOSIS SIGNAL REGULATING KINASE 1; ASPARTATE AMINOTRANSFERASE; CYSTEINE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1; PROTEIN MDM2; PROTEIN P53; PROTEIN SERINE THREONINE KINASE; PROTEIN SERINE THREONINE KINASE 38; RECEPTOR INTERACTING PROTEIN SERINE THREONINE KINASE; SERINE; SERINE THREONINE KINASE RECEPTOR ASSOCIATED PROTEIN; SHORT HAIRPIN RNA; SMAD3 PROTEIN; TRANSCRIPTION FACTOR AP 1; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; MAP3K5 PROTEIN, MOUSE; MELK PROTEIN, MOUSE; PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING) KINASE; SIGNAL TRANSDUCING ADAPTOR PROTEIN; SMALL INTERFERING RNA; STRAP PROTEIN, MOUSE;

AMINO ACID SUBSTITUTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL CYCLE ARREST; CELL DEATH; CELL PROLIFERATION; COMPLEX FORMATION; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; GENE EXPRESSION; GENE SILENCING; HEK293 CELL LINE; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; OXIDATION REDUCTION STATE; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TRANSACTIVATION; UBIQUITINATION; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CELL LINE; CHEMISTRY; DEFICIENCY; DRUG EFFECTS; GENETICS; HUMAN; METABOLISM; PHOSPHORYLATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; APOPTOSIS; CELL LINE; DINITROCHLOROBENZENE; HEK293 CELLS; HUMANS; MALE; MAP KINASE KINASE KINASE 5; MICE; MICE, INBRED C57BL; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; RNA, SMALL INTERFERING; SERINE; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84915785527     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/15384101.2014.952165     Document Type: Article

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