Molecular Mechanisms Associated with Nosocomial Carbapenem-resistant Acinetobacter baumannii in Mexico

Archives of Medical Research

Volumn 45, Issue 7, 2014, Pages 553-560

  Alcántar Curiel, María Dolores ^a   García Torres, Luis Francisco ^a,b   González Chávez, María Inés ^a,b   Morfín Otero, Rayo ^c   Gayosso Vázquez, Catalina ^a   Jarillo Quijada, Ma Dolores ^a   Fernández Vázquez, José Luis ^a   Giono Cerezo, Silvia ^b   Rodríguez Noriega, Eduardo ^c   Santos Preciado, José Ignacio ^a  

^a UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^b INSTITUTO POLITÉCNICO NACIONAL   (Mexico)

^c HOSPITAL CIVIL DE GUADALAJARA FRAY ANTONIO ALCALDE   (Mexico)

Author keywords

Acinetobacter baumannii; Carbapenem; Nosocomial infections; OXA 72; Resistance

Indexed keywords

CARBAPENEM; CARBAPENEMASE; CARBONYL CYANIDE CHLOROPHENYLHYDRAZONE; IMIPENEM; MEROPENEM; METALLO BETA LACTAMASE; OUTER MEMBRANE PROTEIN; ANTIINFECTIVE AGENT; BACTERIAL PROTEIN; BETA LACTAMASE; CARBAPENEM DERIVATIVE; CARBONYL 3-CHLOROPHENYLHYDRAZONE; HYDRAZONE DERIVATIVE; THIENAMYCIN DERIVATIVE;

ACINETOBACTER BAUMANNII; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIUM ISOLATE; GENETIC VARIABILITY; HOSPITAL INFECTION; MEXICO; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PHYLOGENETIC TREE; PROTEIN EXPRESSION; PULSED FIELD GEL ELECTROPHORESIS; ACINETOBACTER INFECTIONS; CROSS INFECTION; DRUG EFFECTS; GENETICS; HOSPITAL; HUMAN; ISOLATION AND PURIFICATION; METABOLISM; MICROBIAL SENSITIVITY TEST; MICROBIOLOGY; MULTIDRUG RESISTANCE; TRANSPORT AT THE CELLULAR LEVEL;

ACINETOBACTER BAUMANNII; ACINETOBACTER INFECTIONS; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; BETA-LACTAMASES; BIOLOGICAL TRANSPORT; CARBAPENEMS; CROSS INFECTION; DRUG RESISTANCE, MULTIPLE, BACTERIAL; ELECTROPHORESIS, GEL, PULSED-FIELD; HOSPITALS; HUMANS; HYDRAZONES; IMIPENEM; MEXICO; MICROBIAL SENSITIVITY TESTS; THIENAMYCINS;

EID: 84915782199     PISSN: 01884409     EISSN: 18735487     Source Type: Journal    
DOI: 10.1016/j.arcmed.2014.10.006     Document Type: Article

References (35)

1. Richet H., Fournier P.E. Nosocomial infections caused by Acinetobacter baumannii: a major threat worldwide. Infect Control Hosp Epidemiol 2006, 27:645-646.
2. Sader H.S., Jones R.N., Andrade-Baiocchi S., et al. Four-year evaluation of frequency of occurrence and antimicrobial susceptibility patterns of bacteria from bloodstream infections in Latin American medical centers. Diagn Microbiol Infect Dis 2002, 44:273-280.
3. Villegas M.V., Hartstein A.I. Acinetobacter outbreaks, 1977-2000. Infect Control Hosp Epidemiol 2003, 24:284-295.
4. Peleg A.Y., Seifert H., Paterson D.L. Acinetobacter baumannii. Emergence of a successful pathogen. Clin Microbiol Rev 2008, 21:538-582.
5. Pérez F., Huger A.M., Huger K.M., et al. Global challenge of multidrug-resistant Acinetobacter baumannii. Antimicrobial Agents Chemother 2007, 51:2471-3484.
6. Morfín-Otero R., Alcántar-Curiel M.D., Rocha M.J., et al. Acinetobacter baumannii infections in a tertiary care hospital in Mexico over the past 13 years. Chemotherapy 2013, 58:57-65.
7. Walsh T.R., Bolmström A., Qwärnström A., et al. Evaluation of a new E-test for detecting metallo-β-lactamases in routine clinical testing. J Clin Microbiol 2002, 40:2755-2759.
8. Walther-Rasmussen J., Hoiby N. OXA-type carbapenemases. J Antimicrob Chemother 2006, 57:373-383.
9. Fernández-Cuenca F., Martínez-Martínez L., Conejo M.C., et al. Relationship between beta-lactamase production, outer membrane protein and penicillin-binding protein profiles on the activity of carbapenems against clinical isolates of Acinetobacter baumannii. J Antimicrob Chemother 2003, 51:565-574.
10. Huang L., Sun L., Xu G., et al. Differential susceptibility to carbapenems due to the AdeABC efflux pump among nosocomial outbreak isolates of Acinetobacter baumannii in a Chinese hospital. Diagn Microbiol Infect Dis 2008, 62:326-332.
11. Damier-Piolle L., Magnet S., Brémont S., et al. AdeIJK, a resistance-nodulation-cell division pump effluxing multiple antibiotics in Acinetobacter baumannii. Antimicrob Agents Chemother 2008, 52:557-562.
12. Limansky A.S., Mussi M.A., Viale A. Loss of a 29-kilodalton outer membrane protein in Acinetobacter baumannii is associated with imipenem resistance. J Clin Microbiol 2002, 40:4776-4778.
13. Poirel L., Nordmann P. Carbapenem resistance in Acinetobacter baumannii: mechanisms and epidemiology. Clin Microbiol Infect 2006, 12:826-836.
14. Gerner-Smidt P., Tjernberg I., Ursing J. Reliability of phenotypic test for identification of Acinetobacter species. J Clin Microbiol 1991, 29:277-282.
15. OxA-51-like carbapenemase gene intrinsic to this species. J Clin Microbiol 2006, 44:2974-2976.
16. Horan T.C., Andrus M., Dudeck M.A. CDC/NHSN surveillance definition of health care-associated infection and criteria for specific types of infections in the acute care setting. Am J Infect Control 2008, 36:309-332.
17. Clinical and Laboratory Standards Institute Performance Standards for Antimicrobial Susceptibility Twentieth Informational Supplement M100-S20 2014, CLSI, Wayne, PA.
18. Lee K., Chong Y., Shin H.B., et al. Modified Hodge and EDTA-disk synergy tests to screen metallo-β-lactamase-producing strains of Pseudomonas and Acinetobacter species. Clin Microbiol Infect Dis 2001, 7:88-91.
19. IMP) in gram-negative rods resistant to broad-spectrum β-lactams. J Clin Microbiol 1996, 34:2909-2913.
20. Jeong S.H., Bae I.K., Park K.O., et al. Outbreaks of imipenem-resistant Acinetobacter baumannii producing carbapenemases in Korea. J Microbiol 2006, 44:423-431.
21. Ames G.F. Resolution of bacterial proteins by polyacrylamide gel electrophoresis on slabs. Membrane, soluble, and periplasmic fractions. J Biol Chem 1974, 25(249):634-644.
22. Nass T., Levy M., Hirschauer C., et al. Outbreak of carbapenem-resistant Acinetobacter baumannii producing the carbapenemase OXA-23 in a tertiary care hospital of Papeete, French Polynesia. J Clin Microbiol 2005, 43:4826-4829.
23. Tenover F.C., Arbeit R.D., Goering R.V., et al. Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing. J Clin Microbiol 1995, 33:2233-2239.
24. Dice L.R. Measures of the amount of ecologic association between species. Ecology 1945, 26:299-302.
25. Bou G., Cerveró G., Domínguez M.A., et al. Characterization of a nosocomial outbreak caused by a multiresistant Acinetobacter baumannii strain with a carbapenem-hydrolyzing enzyme: high-level carbapenem resistance in A. baumannii is not due solely to the presence of β-lactamases. J Clin Microbiol 2000, 38:3299-3305.
26. Maya J.J., Ruiz S.J., Blanco V.M., et al. Current status of carbapenemases in Latin America. Expert Rev Anti Infect Ther 2013, 11:657-667.
27. OxA-72 in Taiwan. BMC Infect Dis 2013, 13:319.
28. Montealegre M.C., Maya J.J., Correa A., et al. First identification of OXA-72 carbapenemase from Acinetobacter pitti in Colombia. Antimicrob Agents Chemother 2012, 56:3996-3998.
29. Giannouli M., Tomasone F., Agodi A., et al. Molecular epidemiology of carbapenem-resistant Acinetobacter baumannii strains in intensive care units of multiple Mediterranean hospitals. J Antimicrob Chemother 2009, 63:828-830.
30. VIM genes among Acinetobacter baumannii isolated from two hospitals of Tehran, Iran. Scientifica (Cairo) 2014, 2014:245162.
31. Héritier C., Poirel L., Lambert T., et al. Contribution of acquired carbapenem-hydrolyzing oxacillinases to carbapenem resistance in Acinetobacter baumannii. Antimicrob Agents Chemother 2005, 49:3198-3202.
32. Huang J., Huang J., Yu F., et al. AdeABC efflux pump: less important role in Acinetobacter baumannii against carbapenems. Afr J Microbiol Res 2010, 4:2148-2152.
33. Dupont M., Pagès J.M., Lafitte D., et al. Identification of an OprD homologue in Acinetobacter baumannii. J Proteome Res 2005, 4:2386-2390.
34. Köhler T., EPP S.F., Curty L.K., et al. Characterization of MexT, theregulator of the MexE-MexF-OprN multidrug efflux systemofPseudomonas aeruginosa. J Bacteriol 1999, 181:6300-6305.
35. Garza-González E., Llaca-Díaz J.M., Bosques-Padilla F., et al. Prevalence of multidrug-resistant bacteria at a tertiary-care teaching hospital in Mexico: Special focus on Acinetobacter baumannii. Chemotherapy 2012, 56:275-279.