Molecular epidemiology of carbapenem-resistant Acinetobacter baumannii strains in intensive care units of multiple Mediterranean hospitals

Journal of Antimicrobial Chemotherapy

Volumn 63, Issue 4, 2009, Pages 828-830

  Giannouli, Maria ^a   Tomasone, Federica ^a   Agodi, Antonella ^b   Vahaboglu, Haluk ^c   Daoud, Ziad ^d   Triassi, Maria ^a   Tsakris, Athanassios ^e   Zarrilli, Raffaele ^a,f  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b UNIVERSITY OF CATANIA   (Italy)

^c KOCAELI UNIVERSITY   (Turkey)

^d UNIVERSITY OF BALAMAND   (Lebanon)

^e UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^f CEINGE BIOTECNOLOGIE AVANZATE   (Italy)

Author keywords

A. baumannii; Carbapenemases; Genotyping; IS elements; Nosocomial outbreaks

Indexed keywords

CARBAPENEM; IMIPENEM; MEROPENEM;

ACINETOBACTER BAUMANNII; ANTIBIOTIC SENSITIVITY; BACTERIAL STRAIN; BACTERIUM ISOLATION; CONTROLLED STUDY; EPIDEMIC; GENE IDENTIFICATION; GENOTYPE; GEOGRAPHIC DISTRIBUTION; HOSPITAL INFECTION; HUMAN; INTENSIVE CARE UNIT; LETTER; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR CLONING; MOLECULAR EPIDEMIOLOGY; MULTIPLEX POLYMERASE CHAIN REACTION; NONHUMAN; NUCLEOTIDE SEQUENCE; SOUTHERN EUROPE; SPECIES DISTRIBUTION;

ACINETOBACTER BAUMANNII; ACINETOBACTER INFECTIONS; ANTI-BACTERIAL AGENTS; BACTERIAL TYPING TECHNIQUES; BETA-LACTAMASES; CARBAPENEMS; DNA FINGERPRINTING; DNA, BACTERIAL; DRUG RESISTANCE, BACTERIAL; ELECTROPHORESIS, GEL, PULSED-FIELD; EPIDEMIOLOGY, MOLECULAR; GENES, BACTERIAL; GENOTYPE; HOSPITALS; HUMANS; INTENSIVE CARE UNITS; MEDITERRANEAN REGION;

EID: 62549154085     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkp032     Document Type: Letter

References (8)

1. Peleg AY, Seifert H, Paterson DL. Acinetobacter baumannii: emergence of a successful pathogen. Clin Microbiol Rev 2008; 21 538-82.
2. Turton JF, Gabriel SN, Valderrey C et al. Use of sequence-based typing and multiplex PCR to identify clonal lineages of outbreak strains of Acinetobacter baumannii. Clin Microbiol Infect 2007; 13: 807-15.
3. Pournaras S, Markogiannakis A, Ikonomidis A et al. Outbreak of multiple clones of imipenem-resistant Acinetobacter baumannii isolates expressing OXA-58 carbapenemase in an intensive care unit. J Antimicrob Chemother 2006; 57: 557-61.
4. Vahaboglu H, Budak F, Kasap M et al. High prevalence of OXA-51-type class D β-lactamases among ceftazidime-resistant clinical isolates of Acinetobacter spp.: Co-existence with OXA-58 in multiple centres. J Antimicrob Chemother 2006; 58: 537-42.
5. Zarrilli R, Casillo R, Di Popolo A et al. Molecular epidemiology of a clonal outbreak of multidrug-resistant Acinetobacter baumannii in a university hospital in Italy. Clin Microbiol Infect 2007; 13: 481-9.
6. XA-58 gene confers imipenem resistance to Acinetobacter baumannii isolates from a Lebanese hospital. Antimicrob Agents Chemother 2008; 52: 4115-20.
7. Clinical and Laboratory Standards Institute. Performance Standards for Antimicrobial Susceptibility Testing: Eighteenth Informational Supplement M100-S18. CLSI, Wayne, PA, USA, 2008.
8. XA-58 in Acinetobacter baumannii. Antimicrob Agents Chemother 2006; 50: 1442-8.