Podoplanin requires sialylated O-glycans for stable expression on lymphatic endothelial cells and for interaction with platelets

Blood

Volumn 124, Issue 24, 2014, Pages 3656-3665

  Pan, Yanfang ^a,c   Yago, Tadayuki ^a   Fu, Jianxin ^a,d   Herzog, Brett ^a,b   McDaniel, J Michael ^a   Mehta D'Souza, Padmaja ^a   Cai, Xiaofeng ^a   Ruan, Changgeng ^d   McEver, Rodger P ^a,b   West, Christopher ^b   Dai, Kesheng ^d   Chen, Hong ^a,b   Xia, Lijun ^a,b,d  

^a OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

^b UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^c ZHEJIANG PROVINCIAL CENTER FOR DISEASE CONTROL AND PREVENTION   (China)

^d Key Laboratory of Thrombosis and Hemostasis of Ministry of Health   (China)

Author keywords

[No Author keywords available]

Indexed keywords

GELATINASE A; GELATINASE B; GLYCAN; ILOMASTAT; PODOPLANIN; SIALIDASE; DIPEPTIDE; GP38 PROTEIN, MOUSE; MATRIX METALLOPROTEINASE INHIBITOR; MEMBRANE PROTEIN; MMP2 PROTEIN, MOUSE; MMP9 PROTEIN, MOUSE; N-(2(R)-2-(HYDROXAMIDOCARBONYLMETHYL)-4-METHYLPENTANOYL)-L-TRYPTOPHAN METHYLAMIDE; POLYSACCHARIDE; SIALIC ACID DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ENDOTHELIUM CELL; INCUBATION TIME; LIGATION; LYMPH VESSEL ENDOTHELIUM; LYMPHATIC ENDOTHELIAL CELL; MOUSE; NONHUMAN; PLATELET INTERACTION; PROTEIN DEGRADATION; PUNCTURE; SEPSIS; SIALYLATION; STABLE EXPRESSION; THROMBOCYTE; THROMBOCYTE ADHESION; THROMBOCYTE FUNCTION; WILD TYPE; ANIMAL; BIOSYNTHESIS; CELL COMMUNICATION; CHO CELL LINE; CRICETULUS; CYTOLOGY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; GLYCOSYLATION; KNOCKOUT MOUSE; METABOLISM; PHYSIOLOGY;

ANIMALS; BLOOD PLATELETS; CELL COMMUNICATION; CHO CELLS; CRICETULUS; DIPEPTIDES; ENDOTHELIAL CELLS; GENE EXPRESSION REGULATION; GLYCOSYLATION; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MATRIX METALLOPROTEINASE INHIBITORS; MEMBRANE GLYCOPROTEINS; MICE; MICE, KNOCKOUT; PLATELET ADHESIVENESS; POLYSACCHARIDES; SIALIC ACIDS;

EID: 84915751995     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2014-04-572107     Document Type: Article

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