Maresin 1 biosynthesis during platelet-neutrophil interactions is organ-protective

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 46, 2014, Pages 16526-16531

  Abdulnour, Raja Elie E ^a   Dalli, Jesmond ^a,b   Colby, Jennifer K ^a   Krishnamoorthy, Nandini ^a   Timmons, Jack Y ^a   Tan, Sook Hwa ^a   Colas, Romain A ^b   Petasis, Nicos A ^c   Serhan, Charles N ^b   Levy, Bruce D ^a,b  

^a Dept of Pathol   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARACHIDONATE 12 LIPOXYGENASE; DOCOSAHEXAENOIC ACID; EPOXY MARESIN; MARESIN 1; UNCLASSIFIED DRUG; 13,14-DIHYDROXYDOCOSAHEXAENOIC ACID; 7,14-DIHYDROXYDOCOSA-4,8,10,12,16,19-HEXAENOIC ACID; HYDROCHLORIC ACID; RECOMBINANT PROTEIN; THROMBIN; THROMBOCYTE ACTIVATING FACTOR;

ADULT RESPIRATORY DISTRESS SYNDROME; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOSYNTHESIS; CELL INTERACTION; CHEMICAL STRUCTURE; IN VIVO STUDY; NEUTROPHIL; NONHUMAN; THROMBOCYTE; ANIMAL; BAGG ALBINO MOUSE; BRONCHOALVEOLAR LAVAGE FLUID; CELL HYPOXIA; CHEMICALLY INDUCED; CYTOLOGY; DISEASE MODEL; DRUG EFFECTS; HUMAN; INFLAMMATION; LUNG; MALE; METABOLISM; METABOLOMICS; MOUSE; NEUTROPHIL CHEMOTAXIS; PATHOLOGY; PHYSIOLOGY; RESPIRATORY DISTRESS SYNDROME, ADULT; THROMBOCYTE TRANSFUSION; XENOGRAFT;

MURINAE;

ANIMALS; ARACHIDONATE 12-LIPOXYGENASE; BLOOD PLATELETS; BRONCHOALVEOLAR LAVAGE FLUID; CELL HYPOXIA; CHEMOTAXIS, LEUKOCYTE; DISEASE MODELS, ANIMAL; DOCOSAHEXAENOIC ACIDS; HETEROGRAFTS; HUMANS; HYDROCHLORIC ACID; INFLAMMATION; LUNG; MALE; METABOLOMICS; MICE; MICE, INBRED BALB C; MOLECULAR STRUCTURE; NEUTROPHILS; PLATELET ACTIVATING FACTOR; PLATELET TRANSFUSION; RECOMBINANT PROTEINS; RESPIRATORY DISTRESS SYNDROME, ADULT; THROMBIN;

EID: 84915748472     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1407123111     Document Type: Article

References (29)

1. Morris T, et al. (2010) Dichotomy in duration and severity of acute inflammatory responses in humans arising from differentially expressed proresolution pathways. Proc Natl Acad Sci USA 107(19):8842-8847
2. Levy BD, Serhan CN (2014) Resolution of acute inflammation in the lung. Annu Rev Physiol 76:467-492
3. Lehr HA, Frei B, Arfors KE (1994) Vitamin C prevents cigarette smoke-induced leukocyte aggregation and adhesion to endothelium in vivo. Proc Natl Acad Sci USA 91(16):7688-7692
4. Ley K, Laudanna C, Cybulsky MI, Nourshargh S (2007) Getting to the site of inflammation: The leukocyte adhesion cascade updated. Nat Rev Immunol 7(9): 678-689
5. Tabas I, Glass CK (2013) Anti-inflammatory therapy in chronic disease: Challenges and opportunities. Science 339(6116):166-172
6. Matthay MA, Ware LB, Zimmerman GA (2012) The acute respiratory distress syndrome. J Clin Invest 122(8):2731-2740
7. Looney MR, et al. (2009) Platelet depletion and aspirin treatment protect mice in a two-event model of transfusion-related acute lung injury. J Clin Invest 119(11): 3450-3461
8. Zarbock A, Singbartl K, Ley K (2006) Complete reversal of acid-induced acute lung injury by blocking of platelet-neutrophil aggregation. J Clin Invest 116(12):3211-3219
9. Fukunaga K, Kohli P, Bonnans C, Fredenburgh LE, Levy BD (2005) Cyclooxygenase 2 plays a pivotal role in the resolution of acute lung injury. J Immunol 174(8):5033-5039
10. Levy BD, Clish CB, Schmidt B, Gronert K, Serhan CN (2001) Lipid mediator class switching during acute inflammation: Signals in resolution. Nat Immunol 2(7):612-619
11. Serhan CN, et al. (2009) Maresins: Novel macrophage mediators with potent antiinflammatory and proresolving actions. J Exp Med 206(1):15-23
12. Serhan CN, et al. (2012) Macrophage proresolving mediator maresin 1 stimulates tissue regeneration and controls pain. FASEB J 26(4):1755-1765
13. Dalli J, et al. (2013) The novel 13S,14S-epoxy-maresin is converted by human macrophages to maresin 1 (MaR1), inhibits leukotriene A4 hydrolase (LTA4H), and shifts macrophage phenotype. FASEB J 27(7):2573-2583
14. Marik PE (2001) Aspiration pneumonitis and aspiration pneumonia. N Engl J Med 344(9):665-671
15. Hilberath JN, et al. (2011) Resolution of Toll-like receptor 4-mediated acute lung injury is linked to eicosanoids and suppressor of cytokine signaling 3. FASEB J 25(6): 1827-1835
16. Eickmeier O, et al. (2013) Aspirin-triggered resolvin D1 reduces mucosal inflammation and promotes resolution in a murine model of acute lung injury. Mucosal Immunol 6(2):256-266
17. Mitzner W, Brown R, Lee W (2001) In vivo measurement of lung volumes in mice. Physiol Genomics 4(3):215-221
18. Nordgren TM, et al. (2013) Maresin-1 reduces the pro-inflammatory response of bronchial epithelial cells to organic dust. Respir Res 14(1):51
19. Clish CB, Levy BD, Chiang N, Tai HH, Serhan CN (2000) Oxidoreductases in lipoxin A4 metabolic inactivation: A novel role for 15-onoprostaglandin 13-reductase/leukotriene B4 12-hydroxydehydrogenase in inflammation. J Biol Chem 275(33):25372-25380
20. Serhan CN, Sheppard KA (1990) Lipoxin formation during human neutrophil-platelet interactions. Evidence for the transformation of leukotriene A4 by platelet 12-lipoxygenase in vitro. J Clin Invest 85(3):772-780
21. Weyrich AS, Zimmerman GA (2013) Platelets in lung biology. Annu Rev Physiol 75: 569-591
22. Serhan CN (2014) Pro-resolving lipid mediators are leads for resolution physiology. Nature 510(7503):92-101
23. El Kebir D, et al. (2009) 15-epi-lipoxin A4 inhibits myeloperoxidase signaling and enhances resolution of acute lung injury. Am J Respir Crit Care Med 180(4):311-319
24. Seki H, et al. (2010) The anti-inflammatory and proresolving mediator resolvin E1 protects mice from bacterial pneumonia and acute lung injury. J Immunol 184(2): 836-843
25. Ortiz-Muñoz G, et al. (2014) Aspirin-triggered 15-epi-lipoxin A4 regulates neutrophilplatelet aggregation and attenuates acute lung injury in mice. Blood, 0.1182/blood- 2014-03-562876
26. Mantovani A, Cassatella MA, Costantini C, Jaillon S (2011) Neutrophils in the activation and regulation of innate and adaptive immunity. Nat Rev Immunol 11(8): 519-531
27. Wiedermann FJ, et al. (2004) Alveolar granulocyte colony-stimulating factor and alpha-chemokines in relation to serum levels, pulmonary neutrophilia, and severity of lung injury in ARDS. Chest 125(1):212-219
28. Patel BV, Wilson MR, O'Dea KP, Takata M (2013) TNF-induced death signaling triggers alveolar epithelial dysfunction in acute lung injury. J Immunol 190(8):4274-4282
29. Gong J, et al. (2014) Maresin 1 mitigates lipopolysaccharide-induced acute lung injury in mice. Br J Pharmacol 171(14):3539-3550