TNF-induced death signaling triggers alveolar epithelial dysfunction in acute lung injury

Journal of Immunology

Volumn 190, Issue 8, 2013, Pages 4274-4282

  Patel, Brijesh V ^a   Wilson, Michael R ^a   O'Dea, Kieran P ^a   Takata, Masao ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADVANCED GLYCATION END PRODUCT; CASPASE 8; PROTEIN P55; TUMOR NECROSIS FACTOR;

ACID ASPIRATION; ACUTE LUNG INJURY; ALVEOLAR FLUID CLEARANCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL DEATH; CELL FUNCTION; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOKINE PRODUCTION; ENZYME ACTIVATION; ENZYME INHIBITION; FLOW CYTOMETRY; GENE DELETION; IN VIVO STUDY; LUNG ALVEOLUS EPITHELIUM; LUNG ALVEOLUS MACROPHAGE; LUNG EDEMA; MALE; MOUSE; NEUTROPHIL; NONHUMAN; OXYGENATION; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

ACUTE LUNG INJURY; ANIMALS; CASPASE 8; CELL DEATH; INFLAMMATION MEDIATORS; MACROPHAGES, ALVEOLAR; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PULMONARY EDEMA; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE I; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84875993973     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1202437     Document Type: Article

References (55)

1. Ware, L. B., and M. A. Matthay. 2000. The acute respiratory distress syndrome. N. Engl. J. Med. 342: 1334-1349.
2. Rubenfeld, G. D., E. Caldwell, E. Peabody, J. Weaver, D. P. Martin, M. Neff, E. J. Stern, and L. D. Hudson. 2005. Incidence and outcomes of acute lung injury. N. Engl. J. Med. 353: 1685-1693.
3. Wilson, M. R., K. P. O'Dea, D. Zhang, A. D. Shearman, N. van Rooijen, and M. Takata. 2009. Role of lung-marginated monocytes in an in vivo mouse model of ventilator-induced lung injury. Am. J. Respir. Crit. Care Med. 179: 914-922.
4. O'Dea, K. P., M. R. Wilson, J. O. Dokpesi, K. Wakabayashi, L. Tatton, N. van Rooijen, and M. Takata. 2009. Mobilization and margination of bone marrow Gr-1high monocytes during subclinical endotoxemia predisposes the lungs toward acute injury. J. Immunol. 182: 1155-1166.
5. Bdeir, K., A. A. Higazi, I. Kulikovskaya, M. Christofidou-Solomidou, S. A. Vinogradov, T. C. Allen, S. Idell, R. Linzmeier, T. Ganz, and D. B. Cines. 2010. Neutrophil alpha-defensins cause lung injury by disrupting the capillary-epithelial barrier. Am. J. Respir. Crit. Care Med. 181: 935-946.
6. Mokart, D., T. van Craenenbroeck, J. Lambert, J. Textoris, J. P. Brun, A. Sannini, L. Chow-Chine, S. Hamouda, L. Fouché, F. Ettori, et al. 2012. Prognosis of acute respiratory distress syndrome in neutropenic cancer patients. Eur. Respir. J. 40: 169-176.
7. Ognibene, F. P., S. E. Martin, M. M. Parker, T. Schlesinger, P. Roach, C. Burch, J. H. Shelhamer, and J. E. Parrillo. 1986. Adult respiratory distress syndrome in patients with severe neutropenia. N. Engl. J. Med. 315: 547-551.
8. Matt, U., J. M. Warszawska, M. Bauer, W. Dietl, I. Mesteri, B. Doninger, I. Haslinger, G. Schabbauer, T. Perkmann, C. J. Binder, et al. 2009. Bbeta(15-42) protects against acid-induced acute lung injury and secondary pseudomonas pneumonia in vivo. Am. J. Respir. Crit. Care Med. 180: 1208-1217.
9. Dorr, A. D., M. R. Wilson, K. Wakabayashi, A. C. Waite, B. V. Patel, N. van Rooijen, K. P. O'Dea, and M. Takata. 2011. Sources of alveolar soluble TNF receptors during acute lung injury of different etiologies. J. Appl. Physiol. 111: 177-184.
10. Gorin, A. B., and P. A. Stewart. 1979. Differential permeability of endothelial and epithelial barriers to albumin flux. J. Appl. Physiol. 47: 1315-1324.
11. Ware, L. B., and M. A. Matthay. 2001. Alveolar fluid clearance is impaired in the majority of patients with acute lung injury and the acute respiratory distress syndrome. Am. J. Respir. Crit. Care Med. 163: 1376-1383.
12. Martin, T. R., N. Hagimoto, M. Nakamura, and G. Matute-Bello. 2005. Apoptosis and epithelial injury in the lungs. Proc. Am. Thorac. Soc. 2: 214-220.
13. Albertine, K. H., M. F. Soulier, Z. Wang, A. Ishizaka, S. Hashimoto, G. A. Zimmerman, M. A. Matthay, and L. B. Ware. 2002. Fas and fas ligand are up-regulated in pulmonary edema fluid and lung tissue of patients with acute lung injury and the acute respiratory distress syndrome. Am. J. Pathol. 161: 1783-1796.
14. Kitamura, Y., S. Hashimoto, N. Mizuta, A. Kobayashi, K. Kooguchi, I. Fujiwara, and H. Nakajima. 2001. Fas/FasL-dependent apoptosis of alveolar cells after lipopolysaccharide-induced lung injury in mice. Am. J. Respir. Crit. Care Med. 163: 762-769.
15. Matute-Bello, G., W. C. Liles, K. P. Steinberg, P. A. Kiener, S. Mongovin, E. Y. Chi, M. Jonas, and T. R. Martin. 1999. Soluble Fas ligand induces epithelial cell apoptosis in humans with acute lung injury (ARDS). J. Immunol. 163: 2217-2225.
16. Lipke, A. B., G. Matute-Bello, R. Herrero, K. Kurahashi, V. A. Wong, S. M. Mongovin, and T. R. Martin. 2010. Febrile-range hyperthermia augments lipopolysaccharide-induced lung injury by a mechanism of enhanced alveolar epithelial apoptosis. J. Immunol. 184: 3801-3813.
17. Suter, P. M., S. Suter, E. Girardin, P. Roux-Lombard, G. E. Grau, and J. M. Dayer. 1992. High bronchoalveolar levels of tumor necrosis factor and its inhibitors, interleukin-1, interferon, and elastase, in patients with adult respiratory distress syndrome after trauma, shock, or sepsis. Am. Rev. Respir. Dis. 145: 1016-1022.
18. Wilson, M. R., S. Choudhury, M. E. Goddard, K. P. O'Dea, A. G. Nicholson, and M. Takata. 2003. High tidal volume upregulates intrapulmonary cytokines in an in vivo mouse model of ventilator-induced lung injury. J. Appl. Physiol. 95: 1385-1393.
19. Ewart, S., R. Levitt, and W. Mitzner. 1995. Respiratory system mechanics in mice measured by end-inflation occlusion. J. Appl. Physiol. 79: 560-566.
20. Wilson, M. R., M. E. Goddard, K. P. O'Dea, S. Choudhury, and M. Takata. 2007. Differential roles of p55 and p75 tumor necrosis factor receptors on stretch-induced pulmonary edema in mice. Am. J. Physiol. Lung Cell. Mol. Physiol. 293: L60-L68.
21. O'Dea, K. P., J. O. Dokpesi, K. C. Tatham, M. R. Wilson, and M. Takata. 2011. Regulation of monocyte subset proinflammatory responses within the lung microvasculature by the p38 MAPK/MK2 pathway. Am. J. Physiol. Lung Cell. Mol. Physiol. 301: L812-L821.
22. Patel, B. V., M. R. Wilson, and M. Takata. 2012. Resolution of acute lung injury and inflammation: a translational mouse model. Eur. Respir. J. 39: 1162-1170.
23. Unkel, B., K. Hoegner, B. E. Clausen, P. Lewe-Schlosser, J. Bodner, S. Gattenloehner, H. Janßen, W. Seeger, J. Lohmeyer, and S. Herold. 2012. Alveolar epithelial cells orchestrate DC function in murine viral pneumonia. J. Clin. Invest. 122: 3652-3664.
24. Corti, M., A. R. Brody, and J. H. Harrison. 1996. Isolation and primary culture of murine alveolar type II cells. Am. J. Respir. Cell Mol. Biol. 14: 309-315.
25. Bertok, S., M. R. Wilson, A. D. Dorr, J. O. Dokpesi, K. P. O'Dea, N. Marczin, and M. Takata. 2011. Characterization of TNF receptor subtype expression and signaling on pulmonary endothelial cells in mice. Am. J. Physiol. Lung Cell. Mol. Physiol. 300: L781-L789.
26. Herold, S., T. S. Tabar, H. Janssen, K. Hoegner, M. Cabanski, P. Lewe-Schlosser, J. Albrecht, F. Driever, I. Vadasz, W. Seeger, et al. 2011. Exudate macrophages attenuate lung injury by the release of IL-1 receptor antagonist in gram-negative pneumonia. Am. J. Respir. Crit. Care Med. 183: 1380-1390.
27. Uchida, T., M. Shirasawa, L. B. Ware, K. Kojima, Y. Hata, K. Makita, G. Mednick, Z. A. Matthay, and M. A. Matthay. 2006. Receptor for advanced glycation end-products is a marker of type I cell injury in acute lung injury. Am. J. Respir. Crit. Care Med. 173: 1008-1015.
28. Beck-Schimmer, B., D. S. Rosenberger, S. B. Neff, M. Jamnicki, D. Suter, T. Fuhrer, R. Schwendener, C. Booy, L. Reyes, T. Pasch, and R. C. Schimmer. 2005. Pulmonary aspiration: new therapeutic approaches in the experimental model. Anesthesiology 103: 556-566.
29. Monden, Y., T. Kubota, T. Inoue, T. Tsutsumi, S. Kawano, T. Ide, H. Tsutsui, and K. Sunagawa. 2007. Tumor necrosis factor-alpha is toxic via receptor 1 and protective via receptor 2 in a murine model of myocardial infarction. Am. J. Physiol. Heart Circ. Physiol. 293: H743-H753.
30. Peschon, J. J., D. S. Torrance, K. L. Stocking, M. B. Glaccum, C. Otten, C. R. Willis, K. Charrier, P. J. Morrissey, C. B. Ware, and K. M. Mohler. 1998. TNF receptor-deficient mice reveal divergent roles for p55 and p75 in several models of inflammation. J. Immunol. 160: 943-952.
31. Bertok, S., M. R. Wilson, P. J. Morley, R. de Wildt, A. Bayliffe, and M. Takata. 2012. Selective inhibition of intra-alveolar p55 TNF receptor attenuates ventilator-induced lung injury. Thorax 67: 244-251.
32. Wajant, H., K. Pfizenmaier, and P. Scheurich. 2003. Tumor necrosis factor signaling. Cell Death Differ. 10: 45-65.
33. Mackay, F., H. Loetscher, D. Stueber, G. Gehr, and W. Lesslauer. 1993. Tumor necrosis factor alpha (TNF-alpha)-induced cell adhesion to human endothelial cells is under dominant control of one TNF receptor type, TNF-R55. J. Exp. Med. 177: 1277-1286.
34. Schneider-Brachert, W., V. Tchikov, J. Neumeyer, M. Jakob, S. Winoto-Morbach, J. Held-Feindt, M. Heinrich, O. Merkel, M. Ehrenschwender, D. Adam, et al. 2004. Compartmentalization of TNF receptor 1 signaling: internalized TNF receptosomes as death signaling vesicles. Immunity 21: 415-428.
35. Micheau, O., and J. Tschopp. 2003. Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes. Cell 114: 181-190.
36. Borges, V. M., R. W. Vandivier, K. A. McPhillips, J. A. Kench, K. Morimoto, S. D. Groshong, T. R. Richens, B. B. Graham, A. M. Muldrow, L. Van Heule, et al. 2009. TNFalpha inhibits apoptotic cell clearance in the lung, exacerbating acute inflammation. Am. J. Physiol. Lung Cell. Mol. Physiol. 297: L586-L595.
37. Kasahara, Y., R. M. Tuder, L. Taraseviciene-Stewart, T. D. Le Cras, S. Abman, P. K. Hirth, J. Waltenberger, and N. F. Voelkel. 2000. Inhibition of VEGF receptors causes lung cell apoptosis and emphysema. J. Clin. Invest. 106: 1311-1319.
38. Kawasaki, M., K. Kuwano, N. Hagimoto, T. Matsuba, R. Kunitake, T. Tanaka, T. Maeyama, and N. Hara. 2000. Protection from lethal apoptosis in lipopoly-saccharide-induced acute lung injury in mice by a caspase inhibitor. Am. J. Pathol. 157: 597-603.
39. Budinger, G. R. S., G. M. Mutlu, D. Urich, S. Soberanes, L. J. Buccellato, K. Hawkins, S. E. Chiarella, K. A. Radigan, J. Eisenbart, H. Agrawal, et al. 2011. Epithelial cell death is an important contributor to oxidant-mediated acute lung injury. Am. J. Respir. Crit. Care Med. 183: 1043-1054.
40. Narula, J., N. Haider, E. Arbustini, and Y. Chandrashekhar. 2006. Mechanisms of disease: apoptosis in heart failure - seeing hope in death. Nat. Clin. Pract. Cardiovasc. Med. 3: 681-688.
41. Morty, R. E., O. Eickelberg, and W. Seeger. 2007. Alveolar fluid clearance in acute lung injury: what have we learned from animal models and clinical studies? Intensive Care Med. 33: 1229-1240.
42. Berthiaume, Y., and M. A. Matthay. 2007. Alveolar edema fluid clearance and acute lung injury. Respir. Physiol. Neurobiol. 159: 350-359.
43. Braun, C., J. Hamacher, D. R. Morel, A. Wendel, and R. Lucas. 2005. Dichotomal role of TNF in experimental pulmonary edema reabsorption. J. Immunol. 175: 3402-3408.
44. Schug, Z. T., F. Gonzalvez, R. H. Houtkooper, F. M. Vaz, and E. Gottlieb. 2011. BID is cleaved by caspase-8 within a native complex on the mitochondrial membrane. Cell Death Differ. 18: 538-548.
45. Dagenais, A., R. Fréchette, Y. Yamagata, T. Yamagata, J.-F. Carmel, M.-E. Clermont, E. Brochiero, C. Massé, and Y. Berthiaume. 2004. Downregulation of ENaC activity and expression by TNF-alpha in alveolar epithelial cells. Am. J. Physiol. Lung Cell. Mol. Physiol. 286: L301-L311.
46. Ndozangue-Touriguine, O., J. Hamelin, and J. Bréard. 2008. Cytoskeleton and apoptosis. Biochem. Pharmacol. 76: 11-18.
47. Bouvry, D., C. Planès, L. Malbert-Colas, V. Escabasse, and C. Clerici. 2006. Hypoxia-induced cytoskeleton disruption in alveolar epithelial cells. Am. J. Respir. Cell Mol. Biol. 35: 519-527.
48. Bem, R. A., A. W. Farnand, V. Wong, A. Koski, M. E. Rosenfeld, N. van Rooijen, C. W. Frevert, T. R. Martin, and G. Matute-Bello. 2008. Depletion of resident alveolar macrophages does not prevent Fas-mediated lung injury in mice. Am. J. Physiol. Lung Cell. Mol. Physiol. 295: L314-L325.
49. Serrao, K. L., J. D. Fortenberry, M. L. Owens, F. L. Harris, and L. A. Brown. 2001. Neutrophils induce apoptosis of lung epithelial cells via release of soluble Fas ligand. Am. J. Physiol. Lung Cell. Mol. Physiol. 280: L298-L305.
50. Kiener, P. A., P. M. Davis, B. M. Rankin, S. J. Klebanoff, J. A. Ledbetter, G. C. Starling, and W. C. Liles. 1997. Human monocytic cells contain high levels of intracellular Fas ligand: rapid release following cellular activation. J. Immunol. 159: 1594-1598.
51. Kroemer, G., L. Galluzzi, P. Vandenabeele, J. Abrams, E. S. Alnemri, E. H. Baehrecke, M. V. Blagosklonny, W. S. El-Deiry, P. Golstein, D. R. Green, et al; Nomenclature Committee on Cell Death 2009. 2009. Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009. Cell Death Differ. 16: 3-11.
52. Green, D. R. 2005. Apoptotic pathways: ten minutes to dead. Cell 121: 671-674.
53. Chiarugi, A. 2005. "Simple but not simpler": toward a unified picture of energy requirements in cell death. FASEB J. 19: 1783-1788.
54. Matute-Bello, G., C. W. Frevert, and T. R. Martin. 2008. Animal models of acute lung injury. Am. J. Physiol. Lung Cell. Mol. Physiol. 295: L379-L399.
55. Ware, L. B. 2008. Modeling human lung disease in animals. Am. J. Physiol. Lung Cell. Mol. Physiol. 294: L149-L150.