Association of Superoxide dismutases (SOD1 and SOD2) and Glutathione peroxidase 1 (GPx1) gene polymorphisms with type 2 diabetes mellitus

Free Radical Research

Volumn 49, Issue 1, 2015, Pages 17-24

  Vats, P ^a   Sagar, N ^a   Singh, T P ^b   Banerjee, Monisha ^a  

^a UNIVERSITY OF LUCKNOW   (India)

^b Balrampur Hospital   (India)

Author keywords

Antioxidant enzymes; Gene polymorphism; Oxidative stress; Reactive metabolites; Type 2 diabetes mellitus

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE; GENOMIC DNA; GLUTATHIONE PEROXIDASE 1; MANGANESE SUPEROXIDE DISMUTASE; GLUTATHIONE PEROXIDASE; SUPEROXIDE DISMUTASE;

ADULT; ARTICLE; BIOCHEMISTRY; BLOOD SAMPLING; CONTROLLED STUDY; DNA EXTRACTION; DNA POLYMORPHISM; FEMALE; GENE FREQUENCY; GENE INTERACTION; GENE LINKAGE DISEQUILIBRIUM; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HETEROZYGOSITY; HUMAN; INDIA; INDIAN; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SINGLE NUCLEOTIDE POLYMORPHISM; BLOOD; CASE CONTROL STUDY; DEMOGRAPHY; ENZYMOLOGY; GENETIC PREDISPOSITION; GENETICS; METABOLISM; OXIDATIVE STRESS;

CASE-CONTROL STUDIES; DEMOGRAPHY; DIABETES MELLITUS, TYPE 2; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; GLUTATHIONE PEROXIDASE; HUMANS; INDIA; OXIDATIVE STRESS; POLYMORPHISM, SINGLE NUCLEOTIDE; SUPEROXIDE DISMUTASE;

EID: 84915746812     PISSN: 10715762     EISSN: 10292470     Source Type: Journal    
DOI: 10.3109/10715762.2014.971782     Document Type: Article

References (37)

1. Banerjee M, Vats P. Reactive metabolites and antioxidant gene polymorphisms in Type2 diabetes mellitus. Redox Biol 2014;2:170-177.
2. Igor NZ, Thomas J, Mariani F, Rodney J. Superoxide dismutase multigene family: a comparison of the CuZn-SOD (SOD1), Mn-SOD (SOD2), and EC-SOD (SOD3) gene structures, evolution, and expression. Free Radical Biol Med 2002;33:337-349.
3. Flekac M, Skrha J, Hilgertova J, Lacinova Z, Jarolimkova M. Gene polymorphisms of superoxide dismutases and catalase in diabetes mellitus. BMC Med Genet 2008;9:30.
4. American Diabetes Association. Diagnosis and classification of diabetes mellitus. Diabetes Care 2014;37:581-590.
5. Gautam S, Agrawal CG, Banerjee M. Study of CI962235 (Ins1361A), rs3212018 (16 bp del) and rs1049673 (G > C) CD36 gene polymorphisms in T2DM patients of North India. Indian J Med Sci 2013;13:439-445.
6. Friedewald WT, Levy RI, Fredrichson DS. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 1972;18:499-502.
7. Miller SA, Dykes DD, Polesky HF. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 1988;16:1215.
8. Gautam S, Agrawal CG, Bid HK, Banerjee M. Preliminary studies on CD36 gene in Type 2 diabetic patients from north India. Indian J Med Res 2011;134:107-112.
9. Freimer NB, Sabatti C. Guidelines for association studies in Human Molecular Genetics. Hum Mol Genet 2005;14:2481-2483.
10. Shi YY, He L. SHEsis is a powerful software platform for analyses of linkage disequilibrium, haplotype construction, and genetic association at polymorphism loci. Cell Res 2005;15:97-98.
11. Quanto, University of South California (USC), Ver. 1.2.4, 2009. http://biostats.usc.edu/Quanto.html. Accessed on 15th June 2014.
12. International Diabetes Federation. 2014. 6th Edition. http://www.idf.org. Accessed on 15th June 2014.
13. Suarez-Kurtz G. Pharmacogenomics in admixed populations: The Brazilian pharmacogenetics/pharmacogenomics network-REFARGEN. Pharmacogenomics J 2004;4:347-348.
14. Hishida A, Okada R, Naito M, Morita E, Wakai K, Hamajima N, et al. Polymorphisms in genes encoding antioxidant enzymes (SOD2, CAT, GPx, TXNTD, SEPP1, SEP15 and SLES) and risk of chronic kidney disease in Japanese-cross-sectional data from the J-MICC study. J Clin Biochem Nutr 2013;53:1-20.
15. Ukkola O, Erkkila PH, Savolainen MJ, Kes ä niemi YA. Lack of association between polymorphisms of catalase, copper-zinc superoxide dismutase (SOD), extracellular SOD and endothelial nitric oxide synthase genes and macroangiopathy in patients with type 2 diabetes mellitus. J Intern Med 2001;249:451-459.
16. Ghattas MH, Abo-Elmatty DM. Association of polymorphic markers of the catalase and superoxide dismutase genes with type 2 diabetes mellitus. DNA Cell Biol 2012;31:1598-1603.
17. Sutton A, Imbert A, Igoudjil A, Descatoire V, Cazanave S, Pessayre D, et al. The manganese superoxide dismutase Ala16val dimorphism modulates both mitochondrial import and mRNA stability. Pharmacogenet Genomics 2005;15:311-319.
18. Kucukgergin C, Sanli O, Amasyali AS, Tefik T, Seckin S. Genetic variants of MnSOD and GPX1 and susceptibility to bladder cancer in a Turkish population. Med Oncol 2012;29:1928-1934.
19. Chistyakov DA, Savost'anov KV, Zotova EV, Nosikov VV. Polymorphisms in the Mn-SOD and EC-SOD genes and their relationship to diabetic neuropathy in type 1 diabetes mellitus. BMC Med Genet 2001;2:4-10.
20. Nomiyama T, Tanaka Y, Piao L, Nagasaka K, Sakai K, Ogihara T, et al. The polymorphism of manganese supero xide dismutase is associated with diabetic nephropathy in Japanese type 2 diabetic patients. J Hum Genet 2003;48:138-141.
21. Ascencio-Montiel IJ, Parra EJ, Valladares-Salgado A, Gomez-Zamudio JH, Kumate-Rodriguez J, Escobedo-de-la-Pena J, et al. SOD2 gene Val16Ala polymorphism is associated with macroalbuminuria in Mexican Type 2 Diabetes patients: a comparative study and meta-analysis. BMC Med Genet 2013;14:110.
22. Lee SJ, Choi MG. Association of manganese superoxide dismutase gene polymorphism (V16A) with diabetic macular edema in Korean type 2 diabetic patients. Metabolism 2006;55:1681-1688.
23. Petrovi MG, Cilensekb I, Petrovi D. Manganese superoxide dismutase gene polymorphism (V16A) is associated with diabetic retinopathy in Slovene (Caucasians) type 2 diabetes patients. Dis Markers 2008;24:59-64.
24. Kangas-Kontio T, Vavuli S, Kakko SJ, Penna J, Savolainen ER, Savolainen MJ, Liinamaa MJ. Polymorphism of the manganese superoxide dismutase gene but not of vascular endothelial growth factor gene is a risk factor for diabetic retinopathy. Br J Ophthalmol 2009;93:10.
25. Tiwari AK, Prasad P, Thelma BK, Kumar KM, Ammini AC, Gupta A, Gupta R. Oxidative stress pathway genes and chronic renal insufficiency in Asian Indian with Type 2 Diabetes. J Diabetes complication 2009;23:102-111.
26. Prabhakar R, Morokuma K, Musaev DG. Peroxynitrite reductase activity of selenoprotein glutathione peroxidase: a computational study. Biochemistry 2006;45:6967-6977.
27. Moscow JA, Schmidt L, Ingram DT, Gnarra J, Johnson B, Cowan KH. Loss of heterozygosity of the human cytosolic glutathione peroxidase I gene in lung cancer. Carcinogenesis 1994;15:2769-2773.
28. Ravn-Haren G, Olsen A, Tjonneland A, Dragsted LO, Nexo BA, Wallin H, et al. Associations between GPX1 Pro198Leu polymorphism, erythrocyte GPX activity, alcohol consumption and breast cancer risk in a prospective cohort study. Carcinogenesis 2006;27:820-825.
29. Blankenberg S, Rupprecht HJ, Bickel C, Torzewski M, Hafner G, Tiret L, et al.; AtheroGene Investigators. Glutathione peroxidase 1 activity and cardiovascular events in patients with coronary artery disease. N Engl J Med 2003;349:1605-1613.
30. Ratnasinghe D, Tangrea JA, Andersen MR, Barrett MJ, Virtamo J, Taylor PR, Albanes D. Glutathione peroxidase codon 198 polymorphism variant increases lung cancer risk. Cancer Res 2000;60:6381-6383.
31. Hu YJ, Diamond AM. Role of glutathione peroxidase 1 in breast cancer: loss of heterozygosity and allelic differences in the response to selenium. Cancer Res 2003;63:3347-3351.
32. Ichimura Y, Habuchi T, Tsuchiya N, Wang L, Oyama C, Sato K, et al. Increased risk of bladder cancer associated with a glutathione peroxidase 1 codon 198 variant. J Urol 2004;172:728-732.
33. Hamanishi T, Furuta H, Kato H, Doi A, Tamai M, Shimomura H, et al. Functional variants in the glutathione peroxidase-1 (GPx-1) gene are associated with increased intima-media thickness of carotid arteries and risk of macrovascular diseases in Japanese type 2 diabetic patients. Diabetes 2004;53:2455-2460.
34. Pera J, Slowik A, Dziedzic T, Pulyk R, Wloch D, Szczudlik A. Glutathione peroxidase 1 C593T polymorphism is associated with lobar intracerebral hemorrhage. Cerebrovasc Dis 2008;25:445-449.
35. Tang NP, Wang LS, Yang L, Gu HJ, Sun QM, Cong RH, et al. Genetic variant in glutathione peroxidase 1 gene is associated with an increased risk of coronary artery disease in a Chinese population. Clin Chim Acta 2008;395:89-93.
36. Chen H, Yu M, Li M, Zhao R, Zhu Q, Zhou W, et al. Polymorphic variations in manganese superoxide dismutase (MnSOD), glutathione peroxidase-1 (GPX1), and catalase (CAT) contribute to elevated plasma triglyceride levels in Chinese patients with type 2 diabetes or diabetic cardiovascular disease. Mol Cell Biochem 2012;363:85-91.
37. Janssens ACJW, Moonesinghe R, Yang Q, Steyerberg EW, Duijn CMV, Khoury MJ. The impact of genotype frequencies on the clinical validity of genomic profiling for predicting common chronic diseases. Genetics in Medicine 2007;9:528-535.