Nifedipine promotes the proliferation and migration of breast cancer cells

PLoS ONE

Volumn 9, Issue 12, 2014, Pages

  Guo, Dong Qing ^a   Zhang, Hao ^b   Tan, Sheng Jiang ^c   Gu, Yu Chun ^a  

^a PEKING UNIVERSITY   (China)

^b FUDAN UNIVERSITY   (China)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN PROTEIN; CALCIUM CHANNEL; MITOGEN ACTIVATED PROTEIN KINASE; NIFEDIPINE; POTASSIUM CHLORIDE; VERAPAMIL; BRI3 PROTEIN, HUMAN; MEMBRANE PROTEIN; MICRORNA; MIRN-524 MICRORNA, HUMAN; NERVE PROTEIN;

ANGPTL7 GENE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; BREAST CANCER CELL LINE; BRI3 GENE; CELL MIGRATION; CELL PROLIFERATION; CELL STIMULATION; CELL SURVIVAL; COL14A1 GENE; CONCENTRATION RESPONSE; CONTROLLED STUDY; FEMALE; GENE; GENE EXPRESSION REGULATION; GENE SILENCING; IN VITRO STUDY; IN VIVO STUDY; KCNC4 GENE; MDA MB 231 CELL LINE; METASTASIS; NONHUMAN; PDE4DIP GENE; SIGNAL TRANSDUCTION; SMOC1 GENE; TUMOR GROWTH; TUMOR VOLUME; ANIMAL; BREAST TUMOR; CELL MOTION; DRUG EFFECTS; EXPERIMENTAL MAMMARY NEOPLASM; GENETICS; HUMAN; MCF 7 CELL LINE; MOUSE; NUDE MOUSE; PATHOLOGY; TUMOR CELL LINE;

ANIMALS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MAMMARY NEOPLASMS, EXPERIMENTAL; MAP KINASE SIGNALING SYSTEM; MCF-7 CELLS; MEMBRANE PROTEINS; MICE; MICE, NUDE; MICRORNAS; NEOPLASM METASTASIS; NERVE TISSUE PROTEINS; NIFEDIPINE; VERAPAMIL;

EID: 84914705970     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0113649     Document Type: Article

References (33)

1. Jemal A, Siegel R, Ward E, Hao Y, Xu J, et al. (2008) Cancer statistics, 2008. CA Cancer J Clin. 58:71-96.
2. Ruark E, Snape K, Humburg P, Loveday C, Bajrami I, et al. (2013) Mosaic PPM1D mutations are associated with predisposition to breast and ovarian cancer. Nature. 493:406-410.
3. Stephens PJ, Tarpey PS, Davies H, Van Loo P, Greenman C, et al. (2012) The landscape of cancer genes and mutational processes in breast cancer. Nature. 486:400-404.
4. Ellis MJ, Ding L, Shen D, Luo J, Suman VJ, et al. (2012) Whole-genome analysis informs breast cancer response to aromatase inhibition. Nature. 486:353-360.
5. Opie LH (1987) Calcium channel antagonists, Part I: Fundamental properties: mechanisms, classification, sites of action. Cardiovasc Drugs Ther. 1:411-430.
6. Timcheva CV, Todorov DK (1996) Does verapamil help overcome multidrug resistance in tumor cell lines and cancer patients? J Chemother. 8:295-299.
7. Bandyopadhyay S, Mallik S, Mukhopadhyay A (2013) A Survey and Comparative Study of Statistical Tests for Identifying Differential Expression from Microarray Data. IEEE/ACM Trans Comput Biol Bioinform.
8. Nie L, Oishi Y, Doi I, Shibata H, Kojima I (1997) Inhibition of proliferation of MCF-7 breast cancer cells by a blocker of Ca(2+)-permeable channel. Cell Calcium. 22:75-82.
9. Kaplan NM (1996) Do calcium antagonists cause cancer? Lancet. 348:541-542.
10. Daling JR (1996) Calcium channel blockers and cancer: is an association biologically plausible? Am J Hypertens. 9:713-714.
11. Pahor M, Guralnik JM, Ferrucci L, Corti MC, Salive ME, et al. (1996) Calcium-channel blockade and incidence of cancer in aged populations. Lancet. 348:493-497.
12. Fitzpatrick AL, Daling JR, Furberg CD, Kronmal RA, Weissfeld JL (1997) Use of calcium channel blockers and breast carcinoma risk in postmenopausal women. Cancer. 80:1438-1447.
13. Davis S, Mirick DK (2007) Medication use and the risk of breast cancer. Eur J Epidemiol. 22:319-325.
14. Ahr HJ, Bomhard E, Enzmann H, Karbe E, Mager H, et al. (1998) Calcium channel blockers and the risk of cancer: a preclinical assessment. Cardiovasc Drugs Ther. 12:157-169.
15. Rosenberg L, Rao RS, Palmer JR, Strom BL, Stolley PD, et al. (1998) Calcium channel blockers and the risk of cancer. JAMA. 279:1000-1004.
16. Sorensen HT, Olsen JH, Mellemkjaer L, Marie A, Steffensen FH, et al. (2000) Cancer risk and mortality in users of calcium channel blockers. A cohort study. Cancer. 89:165-170.
17. Taylor JM, Simpson RU (1992) Inhibition of cancer cell growth by calcium channel antagonists in the athymic mouse. Cancer Res. 52:2413-2418.
18. Jensen RL, Wurster RD (2001) Calcium channel antagonists inhibit growth of subcutaneous xenograft meningiomas in nude mice. Surg Neurol. 55:275-283.
19. Louie E, Chen XF, Coomes A, Ji K, Tsirka S, et al. (2013) Neurotrophin-3 modulates breast cancer cells and the microenvironment to promote the growth of breast cancer brain metastasis. Oncogene. 32:4064-4077.
20. Padua D, Zhang XH, Wang Q, Nadal C, Gerald WL, et al. (2008) TGFbeta primes breast tumors for lung metastasis seeding through angiopoietin-like 4. Cell. 133:66-77.
21. Arnold SA, Brekken RA (2009) SPARC: a matricellular regulator of tumorigenesis. J Cell Commun Signal. 3:255-273.
22. Brellier F, Ruggiero S, Zwolanek D, Martina E, Hess D, et al. (2011) SMOC1 is a tenascin-C interacting protein over-expressed in brain tumors. Matrix Biol. 30:225-233.
23. Tai IT, Tang MJ (2008) SPARC in cancer biology: its role in cancer progression and potential for therapy. Drug Resist Updat. 11:231-246.
24. Lew TS, Chang CS, Fang KP, Chen CY, Chen CH, et al. (2004) The involvement of K(v)3.4 voltagegated potassium channel in the growth of an oral squamous cell carcinoma cell line. J Oral Pathol Med. 33:543-549.
25. Shimada H, Kuboshima M, Shiratori T, Nabeya Y, Takeuchi A, et al. (2007) Serum anti-myomegalin antibodies in patients with esophageal squamous cell carcinoma. Int J Oncol. 30:97-103.
26. Bandres E, Malumbres R, Cubedo E, Honorato B, Zarate R, et al. (2007) A gene signature of 8 genes could identify the risk of recurrence and progression in Dukes' B colon cancer patients. Oncol Rep. 17:1089-1094.
27. Wu H, Liu G, Li C, Zhao S (2003) bri3, a novel gene, participates in tumor necrosis factor-alpha-induced cell death. Biochem Biophys Res Commun. 311:518-524.
28. Kim I, Kim HG, Kim H, Kim HH, Park SK, et al. (2000) Hepatic expression, synthesis and secretion of a novel fibrinogen/angiopoietin-related protein that prevents endothelial-cell apoptosis. Biochem J 346 Pt. 3:603-610.
29. Cazes A, Galaup A, Chomel C, Bignon M, Brechot N, et al. (2006) Extracellular matrix-bound angiopoietin-like 4 inhibits endothelial cell adhesion, migration, and sprouting and alters actin cytoskeleton. Circ Res. 99:1207-1215.
30. Bartel DP (2009) MicroRNAs: target recognition and regulatory functions. Cell. 136:215-233.
31. Lu Z, Jiang G, Blume-Jensen P, Hunter T (2001) Epidermal growth factor-induced tumor cell invasion and metastasis initiated by dephosphorylation and downregulation of focal adhesion kinase. Mol Cell Biol. 21:4016-4031.
32. Chen Y, Zhang J, Wang H, Zhao J, Xu C, et al. (2012) miRNA-135a promotes breast cancer cell migration and invasion by targeting HOXA10. BMC Cancer. 12:111.
33. Fuse M, Nohata N, Kojima S, Sakamoto S, Chiyomaru T, et al. (2011) Restoration of miR-145 expression suppresses cell proliferation, migration and invasion in prostate cancer by targeting FSCN1. Int J Oncol. 38:1093-1101.