The PHD finger of p300 influences its ability to acetylate histone and non-histone targets

Journal of Molecular Biology

Volumn 426, Issue 24, 2015, Pages 3960-3972

  Rack, Johannes G M ^a,b   Lutter, Timo ^a   Kjæreng Bjerga, Gro Elin ^a,c   Guder, Corina ^a   Ehrhardt, Christine ^a,d   Värv, Signe ^a   Ziegler, Mathias ^a   Aasland, Rein ^a  

^a UNIVERSITY OF BERGEN   (Norway)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c Uni Research   (Norway)

^d INSTITUTE OF MOLECULAR BIOTECHNOLOGY   (Austria)

Author keywords

acetylation; bromodomain; CBP; RING finger; Rubinstein Taybi syndrome

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; E1A ASSOCIATED P300 PROTEIN; HISTONE; HISTONE ACETYLTRANSFERASE; NONHISTONE PROTEIN; PROTEIN P53; EP300 PROTEIN, HUMAN; PROTEIN BINDING;

ARTICLE; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME MECHANISM; FEMALE; GENE DELETION; HISTONE ACETYLATION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; PHD FINGER; POINT MUTATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTEIN TARGETING; RUBINSTEIN SYNDROME; ACETYLATION; BINDING SITE; BIOCATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; FLUORESCENCE MICROSCOPY; GENETICS; HEK293 CELL LINE; HELA CELL LINE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; METABOLISM; PROTEIN TERTIARY STRUCTURE;

ACETYLATION; BINDING SITES; BIOCATALYSIS; E1A-ASSOCIATED P300 PROTEIN; HEK293 CELLS; HELA CELLS; HISTONES; HUMANS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MICROSCOPY, FLUORESCENCE; MODELS, MOLECULAR; POINT MUTATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY;

EID: 84914705774     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2014.08.011     Document Type: Article

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