Structures of mesophilic and extremophilic citrate synthases reveal rigidity and flexibility for function

Proteins: Structure, Function and Bioinformatics

Volumn 82, Issue 10, 2014, Pages 2657-2670

  Wells, Stephen A ^a   Crennell, Susan J ^b   Danson, Michael J ^b  

^a University of Bath   (United Kingdom)

^b University of Bath   (United Kingdom)

Author keywords

Elastic network; Elnemo; FIRST; Flexible motion; FRODA; Geometric simulation; Psychrophile; Rigidity; Thermophile

Indexed keywords

CITRATE SYNTHASE; BACTERIAL PROTEIN; LIGAND;

ARTICLE; CATALYSIS; CONTROLLED STUDY; COVALENT BOND; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; DECOMPOSITION; HYDROGEN BOND; MESOPHILE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN FUNCTION; PROTEIN STRUCTURE; PSYCHROPHILE; PYROBACULUM AEROPHILUM; PYROCOCCUS FURIOSUS; RIGIDITY; SULFOLOBUS SOLFATARICUS; THERMOPHILE; THERMOPLASMA ACIDOPHILUM; THERMUS THERMOPHILUS; ANIMAL; ARTHROBACTER; BACILLUS SUBTILIS; BINDING SITE; CHEMICAL PHENOMENA; CHEMICAL STRUCTURE; CHEMISTRY; COMPARATIVE STUDY; ENZYME ACTIVE SITE; ENZYME STABILITY; ENZYMOLOGY; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MOLECULAR DYNAMICS; PIG; PROTEIN DATABASE; PYROBACULUM; THERMOPLASMA;

ANIMALS; ARTHROBACTER; BACILLUS SUBTILIS; BACTERIAL PROTEINS; BINDING SITES; CATALYTIC DOMAIN; CITRATE (SI)-SYNTHASE; DATABASES, PROTEIN; ENZYME STABILITY; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; LIGANDS; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; PROTEIN CONFORMATION; PYROBACULUM; PYROCOCCUS FURIOSUS; SULFOLOBUS SOLFATARICUS; SUS SCROFA; THERMOPLASMA; THERMUS THERMOPHILUS;

EID: 84914677823     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.24630     Document Type: Article

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