Cog5-cog7 crystal structure reveals interactions essential for the function of a multisubunit tethering complex

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 44, 2014, Pages 15762-15767

  Ha, Jun Yong ^a   Pokrovskaya, Irina D ^b   Climer, Leslie K ^b   Shimamura, Gregory R ^a   Kudlyk, Tetyana ^b   Jeffrey, Philip D ^a   Lupashin, Vladimir V ^b,c   Hughson, Frederick M ^a  

^a PRINCETON UNIVERSITY   (United States)

^b UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^c TOMSK STATE UNIVERSITY   (Russian Federation)

Author keywords

CATCHR; COG complex; Congenital glycosylation disorder; Golgi; Vesicle fusion

Indexed keywords

CELL SURFACE PROTEIN; CHYMOTRYPSIN; DSL1 PROTEIN; EXOCYST; GLYCOSYLTRANSFERASE; GOLGI ASSOCIATED RETROGRADE PROTEIN COMPLEX; LECTIN; MANNOSE; MULTIPROTEIN COMPLEX; MULTISUBUNIT TETHERING COMPLEX; PEANUT AGGLUTININ; PROTEINASE K; UNCLASSIFIED DRUG; COG5 PROTEIN, HUMAN; COG7 PROTEIN, HUMAN; VESICULAR TRANSPORT ADAPTOR PROTEIN;

ALLELE; ANIMAL EXPERIMENT; ARTICLE; CELL INTERACTION; CELL MIGRATION; COMPLEX FORMATION; CONSERVED OLIGOMERIC GOLGI COMPLEX 5; CONSERVED OLIGOMERIC GOLGI COMPLEX 7; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENTROPY; EXON SKIPPING; GEL PERMEATION CHROMATOGRAPHY; GENETIC TRANSFECTION; GOLGI COMPLEX; HEK293 CELL LINE; HELA CELL LINE; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; KLUYVEROMYCES LACTIS; MISSENSE MUTATION; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN GLYCOSYLATION; SEQUENCE HOMOLOGY; STRUCTURAL HOMOLOGY; X RAY CRYSTALLOGRAPHY; CHEMISTRY; GENETICS; METABOLISM; PROTEIN QUATERNARY STRUCTURE; PROTEIN SECONDARY STRUCTURE;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; CRYSTALLOGRAPHY, X-RAY; HUMANS; MULTIPROTEIN COMPLEXES; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY;

EID: 84914674874     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1414829111     Document Type: Article

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