Overexpression of CD133 enhances chemoresistance to 5-fluorouracil by activating the PI3K/Akt/p70S6K pathway in gastric cancer cells

Oncology Reports

Volumn 32, Issue 6, 2014, Pages 2437-2444

  Zhu, Youlong ^a   Yu, Jiwei ^a   Wang, Shoulian ^a   Lu, Ruiqi ^a   Wu, Jugang ^a   Jiang, Bojian ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

5 FU resistance; CD133; Gastric cancer; Pi3K Akt p70S6K

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; CD133 ANTIGEN; EPIDERMAL GROWTH FACTOR; FLUOROURACIL; MULTIDRUG RESISTANCE PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE B; S6 KINASE; SMALL INTERFERING RNA; ANTINEOPLASTIC ANTIMETABOLITE; GLYCOPROTEIN; LEUKOCYTE ANTIGEN; PEPTIDE;

APOPTOSIS; ARTICLE; CANCER COMBINATION CHEMOTHERAPY; CANCER RESISTANCE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG RESISTANCE; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GASTRIC CANCER CELL LINE; GENE SILENCING; HUMAN; HUMAN CELL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STOMACH CANCER; CELL PROLIFERATION; GENE EXPRESSION; GENETICS; METABOLISM; STOMACH TUMOR; TUMOR CELL LINE;

ANTIGENS, CD; ANTIMETABOLITES, ANTINEOPLASTIC; CELL LINE, TUMOR; CELL PROLIFERATION; DRUG RESISTANCE, NEOPLASM; FLUOROURACIL; GENE EXPRESSION; GLYCOPROTEINS; HUMANS; P-GLYCOPROTEIN; PEPTIDES; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; SIGNAL TRANSDUCTION; STOMACH NEOPLASMS;

EID: 84914665939     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2014.3488     Document Type: Article

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