-
1
-
-
37349020028
-
Hepatitis C: A clinical review
-
Modi, A. A. and Liang, T. J. (2008) Hepatitis C: a clinical review Oral Diseases 14, 10-14
-
(2008)
Oral Diseases
, vol.14
, pp. 10-14
-
-
Modi, A.A.1
Liang, T.J.2
-
2
-
-
34250679750
-
Epidemiology of hepatitis C virus infection
-
Alter, M. J. (2007) Epidemiology of hepatitis C virus infection World J. Gastroenterol. 13, 2436-2441
-
(2007)
World J. Gastroenterol.
, vol.13
, pp. 2436-2441
-
-
Alter, M.J.1
-
3
-
-
84896362785
-
The HCV revolution did not happen overnight
-
Kwong, A. D. (2014) The HCV revolution did not happen overnight ACS Med. Chem. Lett. 5, 214-220
-
(2014)
ACS Med. Chem. Lett.
, vol.5
, pp. 214-220
-
-
Kwong, A.D.1
-
4
-
-
33846106820
-
GB virus B disrupts RIG-I signaling by NS3/4A-mediated cleavage of the adaptor protein MAVS
-
Chen, Z., Benureau, Y., Rijnbrand, R., Yi, J., Wang, T., Warter, L., Lanford, R. E., Weinman, S. A., Lemon, S. M., Martin, A., and Li, K. (2007) GB virus B disrupts RIG-I signaling by NS3/4A-mediated cleavage of the adaptor protein MAVS J. Virol. 81, 964-976
-
(2007)
J. Virol.
, vol.81
, pp. 964-976
-
-
Chen, Z.1
Benureau, Y.2
Rijnbrand, R.3
Yi, J.4
Wang, T.5
Warter, L.6
Lanford, R.E.7
Weinman, S.A.8
Lemon, S.M.9
Martin, A.10
Li, K.11
-
5
-
-
14544280209
-
Immune evasion by hepatitis C virus NS3/4A protease-mediated cleavage of the Toll-like receptor 3 adaptor protein TRIF
-
Li, K., Foy, E., Ferreon, J. C., Nakamura, M., Ferreon, A. C., Ikeda, M., Ray, S. C., Gale, M., Jr., and Lemon, S. M. (2005) Immune evasion by hepatitis C virus NS3/4A protease-mediated cleavage of the Toll-like receptor 3 adaptor protein TRIF Proc. Natl. Acad. Sci. U.S.A. 102, 2992-2997
-
(2005)
Proc. Natl. Acad. Sci. U.S.A.
, vol.102
, pp. 2992-2997
-
-
Li, K.1
Foy, E.2
Ferreon, J.C.3
Nakamura, M.4
Ferreon, A.C.5
Ikeda, M.6
Ray, S.C.7
Gale, M.8
Lemon, S.M.9
-
6
-
-
29144462494
-
Hepatitis C virus protease NS3/4A cleaves mitochondrial antiviral signaling protein off the mitochondria to evade innate immunity
-
Li, X. D., Sun, L., Seth, R. B., Pineda, G., and Chen, Z. J. (2005) Hepatitis C virus protease NS3/4A cleaves mitochondrial antiviral signaling protein off the mitochondria to evade innate immunity Proc. Natl. Acad. Sci. U.S.A. 102, 17717-17722
-
(2005)
Proc. Natl. Acad. Sci. U.S.A.
, vol.102
, pp. 17717-17722
-
-
Li, X.D.1
Sun, L.2
Seth, R.B.3
Pineda, G.4
Chen, Z.J.5
-
7
-
-
80755159054
-
Discovery and development of telaprevir: An NS3-4A protease inhibitor for treating genotype 1 chronic hepatitis C virus
-
Kwong, A. D., Kauffman, R. S., Hurter, P., and Mueller, P. (2011) Discovery and development of telaprevir: an NS3-4A protease inhibitor for treating genotype 1 chronic hepatitis C virus Nat. Biotechnol. 29, 993-1003
-
(2011)
Nat. Biotechnol.
, vol.29
, pp. 993-1003
-
-
Kwong, A.D.1
Kauffman, R.S.2
Hurter, P.3
Mueller, P.4
-
8
-
-
84886602795
-
The discovery and development of boceprevir
-
Rotella, D. P. (2013) The discovery and development of boceprevir Expert Opin. Drug Discovery 8, 1439-1447
-
(2013)
Expert Opin. Drug Discovery
, vol.8
, pp. 1439-1447
-
-
Rotella, D.P.1
-
9
-
-
78650968050
-
Identification and preclinical profile of the novel HCV NS3 protease inhibitor BMS-650032
-
McPhee, F. (2010) Identification and preclinical profile of the novel HCV NS3 protease inhibitor BMS-650032 J. Hepatol. 52, S296
-
(2010)
J. Hepatol.
, vol.52
, pp. 296
-
-
McPhee, F.1
-
10
-
-
78049316315
-
Preclinical characterization of BI 201335, a C-terminal carboxylic acid inhibitor of the hepatitis C virus NS3-NS4A protease
-
White, P. W., Llinais-Brunet, M., Amad, M. a., Bethell, R. C., Bolger, G., Cordingley, M. G., Duan, J., Garneau, M., Lagacé, L., Thibeault, D., and Kukolj, G. (2010) Preclinical characterization of BI 201335, a C-terminal carboxylic acid inhibitor of the hepatitis C virus NS3-NS4A protease Antimicrob. Agents Chemother. 54, 4611-4618
-
(2010)
Antimicrob. Agents Chemother.
, vol.54
, pp. 4611-4618
-
-
White, P.W.1
Llinais-Brunet, M.2
Amad, M.A.3
Bethell, R.C.4
Bolger, G.5
Cordingley, M.G.6
Duan, J.7
Garneau, M.8
Lagacé, L.9
Thibeault, D.10
Kukolj, G.11
-
11
-
-
57049176125
-
Preclinical characteristics of the hepatitis C virus NS3/4A protease inhibitor ITMN-191 (R7227)
-
Seiwert, S. D., Andrews, S. W., Jiang, Y., Serebryany, V., Tan, H., Kossen, K., Rajagopalan, P. T., Misialek, S., Stevens, S. K., Stoycheva, A., Hong, J., Lim, S. R., Qin, X., Rieger, R., Condroski, K. R., Zhang, H., Do, M. G., Lemieux, C., Hingorani, G. P., Hartley, D. P., Josey, J. A., Pan, L., Beigelman, L., and Blatt, L. M. (2008) Preclinical characteristics of the hepatitis C virus NS3/4A protease inhibitor ITMN-191 (R7227) Antimicrob. Agents Chemother. 52, 4432-4441
-
(2008)
Antimicrob. Agents Chemother.
, vol.52
, pp. 4432-4441
-
-
Seiwert, S.D.1
Andrews, S.W.2
Jiang, Y.3
Serebryany, V.4
Tan, H.5
Kossen, K.6
Rajagopalan, P.T.7
Misialek, S.8
Stevens, S.K.9
Stoycheva, A.10
Hong, J.11
Lim, S.R.12
Qin, X.13
Rieger, R.14
Condroski, K.R.15
Zhang, H.16
Do, M.G.17
Lemieux, C.18
Hingorani, G.P.19
Hartley, D.P.20
Josey, J.A.21
Pan, L.22
Beigelman, L.23
Blatt, L.M.24
more..
-
12
-
-
65749112245
-
In vitro activity and preclinical profile of TMC435350, a potent hepatitis C virus protease inhibitor
-
Lin, T.-I., Lenz, O., Fanning, G., Verbinnen, T., Delouvroy, F., Scholliers, A., Vermeiren, K., Rosenquist, A., Edlund, M., Samuelsson, B., Vrang, L., de Kock, H., Wigerinck, P., Raboisson, P., and Simmen, K. (2009) In vitro activity and preclinical profile of TMC435350, a potent hepatitis C virus protease inhibitor Antimicrob. Agents Chemother. 53, 1377-1385
-
(2009)
Antimicrob. Agents Chemother.
, vol.53
, pp. 1377-1385
-
-
Lin, T.-I.1
Lenz, O.2
Fanning, G.3
Verbinnen, T.4
Delouvroy, F.5
Scholliers, A.6
Vermeiren, K.7
Rosenquist, A.8
Edlund, M.9
Samuelsson, B.10
Vrang, L.11
De Kock, H.12
Wigerinck, P.13
Raboisson, P.14
Simmen, K.15
-
13
-
-
73849106636
-
MK-7009, a potent and selective inhibitor of hepatitis C virus NS3/4A protease
-
Liverton, N. J., Carroll, S. S., DiMuzio, J., Fandozzi, C., Graham, D. J., Hazuda, D., Holloway, M. K., Ludmerer, S. W., McCauley, J. A., McIntyre, C. J., Olsen, D. B., Rudd, M. T., Stahlhut, M., and Vacca, J. P. (2010) MK-7009, a potent and selective inhibitor of hepatitis C virus NS3/4A protease Antimicrob. Agents Chemother. 54, 305-311
-
(2010)
Antimicrob. Agents Chemother.
, vol.54
, pp. 305-311
-
-
Liverton, N.J.1
Carroll, S.S.2
Dimuzio, J.3
Fandozzi, C.4
Graham, D.J.5
Hazuda, D.6
Holloway, M.K.7
Ludmerer, S.W.8
McCauley, J.A.9
McIntyre, C.J.10
Olsen, D.B.11
Rudd, M.T.12
Stahlhut, M.13
Vacca, J.P.14
-
14
-
-
84859752422
-
Discovery of MK-5172, a macrocyclic hepatitis C virus NS3/4a protease inhibitor
-
Harper, S., McCauley, J. A., Rudd, M. T., Ferrara, M., DiFilippo, M., Crescenzi, B., Koch, U., Petrocchi, A., Holloway, M. K., Butcher, J. W., Romano, J. J., Bush, K. J., Gilbert, K. F., McIntyre, C. J., Nguyen, K. T., Nizi, E., Carroll, S. S., Ludmerer, S. W., Burlein, C., DiMuzio, J. M., Graham, D. J., McHale, C. M., Stahlhut, M. W., Olsen, D. B., Monteagudo, E., Cianetti, S., Giuliano, C., Pucci, V., Trainor, N., Fandozzi, C. M., Rowley, M., Coleman, P. J., Vacca, J. P., Summa, V., and Liverton, N. J. (2012) Discovery of MK-5172, a macrocyclic hepatitis C virus NS3/4a protease inhibitor ACS Med. Chem. Lett. 3, 332-336
-
(2012)
ACS Med. Chem. Lett.
, vol.3
, pp. 332-336
-
-
Harper, S.1
McCauley, J.A.2
Rudd, M.T.3
Ferrara, M.4
Difilippo, M.5
Crescenzi, B.6
Koch, U.7
Petrocchi, A.8
Holloway, M.K.9
Butcher, J.W.10
Romano, J.J.11
Bush, K.J.12
Gilbert, K.F.13
McIntyre, C.J.14
Nguyen, K.T.15
Nizi, E.16
Carroll, S.S.17
Ludmerer, S.W.18
Burlein, C.19
Dimuzio, J.M.20
Graham, D.J.21
McHale, C.M.22
Stahlhut, M.W.23
Olsen, D.B.24
Monteagudo, E.25
Cianetti, S.26
Giuliano, C.27
Pucci, V.28
Trainor, N.29
Fandozzi, C.M.30
Rowley, M.31
Coleman, P.J.32
Vacca, J.P.33
Summa, V.34
Liverton, N.J.35
more..
-
15
-
-
75149151884
-
Resistance to direct antiviral agents in patients with hepatitis C virus infection
-
Sarrazin, C. and Zeuzem, S. (2010) Resistance to direct antiviral agents in patients with hepatitis C virus infection Gastroenterology 138, 447-462
-
(2010)
Gastroenterology
, vol.138
, pp. 447-462
-
-
Sarrazin, C.1
Zeuzem, S.2
-
16
-
-
78650481557
-
Drug resistance against HCV NS3/4A inhibitors is defined by the balance of substrate recognition versus inhibitor binding
-
Romano, K. P., Ali, A., Royer, W. E., and Schiffer, C. A. (2010) Drug resistance against HCV NS3/4A inhibitors is defined by the balance of substrate recognition versus inhibitor binding Proc. Natl. Acad. Sci. U.S.A. 107, 20986-20991
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 20986-20991
-
-
Romano, K.P.1
Ali, A.2
Royer, W.E.3
Schiffer, C.A.4
-
17
-
-
84880538921
-
Evaluating the role of macrocycles in the susceptibility of hepatitis C virus NS3/4A protease inhibitors to drug resistance
-
Ali, A., Aydin, C., Gildemeister, R., Romano, K. P., Cao, H., Ozen, A., Soumana, D., Newton, A., Petropoulos, C. J., Huang, W., and Schiffer, C. A. (2013) Evaluating the role of macrocycles in the susceptibility of hepatitis C virus NS3/4A protease inhibitors to drug resistance ACS Chem. Biol. 8, 1469-1478
-
(2013)
ACS Chem. Biol.
, vol.8
, pp. 1469-1478
-
-
Ali, A.1
Aydin, C.2
Gildemeister, R.3
Romano, K.P.4
Cao, H.5
Ozen, A.6
Soumana, D.7
Newton, A.8
Petropoulos, C.J.9
Huang, W.10
Schiffer, C.A.11
-
18
-
-
84866334428
-
Preclinical profile and characterization of the hepatitis C virus NS3 protease inhibitor asunaprevir (BMS-650032)
-
McPhee, F., Sheaffer, A. K., Friborg, J., Hernandez, D., Falk, P., Zhai, G., Levine, S., Chaniewski, S., Yu, F., Barry, D., Chen, C., Lee, M. S., Mosure, K., Sun, L. Q., Sinz, M., Meanwell, N. A., Colonno, R. J., Knipe, J., and Scola, P. (2012) Preclinical profile and characterization of the hepatitis C virus NS3 protease inhibitor asunaprevir (BMS-650032) Antimicrob. Agents Chemother. 56, 5387-5396
-
(2012)
Antimicrob. Agents Chemother.
, vol.56
, pp. 5387-5396
-
-
McPhee, F.1
Sheaffer, A.K.2
Friborg, J.3
Hernandez, D.4
Falk, P.5
Zhai, G.6
Levine, S.7
Chaniewski, S.8
Yu, F.9
Barry, D.10
Chen, C.11
Lee, M.S.12
Mosure, K.13
Sun, L.Q.14
Sinz, M.15
Meanwell, N.A.16
Colonno, R.J.17
Knipe, J.18
Scola, P.19
-
19
-
-
84862560600
-
Resistance analysis of the hepatitis C virus NS3 protease inhibitor asunaprevir
-
McPhee, F., Friborg, J., Levine, S., Chen, C., Falk, P., Yu, F., Hernandez, D., Lee, M. S., Chaniewski, S., Sheaffer, A. K., and Pasquinelli, C. (2012) Resistance analysis of the hepatitis C virus NS3 protease inhibitor asunaprevir Antimicrob. Agents Chemother. 56, 3670-3681
-
(2012)
Antimicrob. Agents Chemother.
, vol.56
, pp. 3670-3681
-
-
McPhee, F.1
Friborg, J.2
Levine, S.3
Chen, C.4
Falk, P.5
Yu, F.6
Hernandez, D.7
Lee, M.S.8
Chaniewski, S.9
Sheaffer, A.K.10
Pasquinelli, C.11
-
20
-
-
84892761609
-
Efficacy of an interferon- and ribavirin-free regimen of daclatasvir, asunaprevir, and BMS-791325 in treatment-naive patients with HCV genotype 1 Infection
-
Everson, G. T., Sims, K. D., Rodriguez-Torres, M., Hézode, C., Lawitz, E., Bourliere, M., Loustaud-Ratti, V., Rustgi, V., Schwartz, H., Tatum, H., Marcellin, P., Pol, S., Thuluvath, P. J., Eley, T., Wang, X., Huang, S.-P., McPhee, F., Wind-Rotolo, M., Chung, E., Pasquinelli, C., Grasela, D. M., and Gardiner, D. F. (2014) Efficacy of an interferon- and ribavirin-free regimen of daclatasvir, asunaprevir, and BMS-791325 in treatment-naive patients with HCV genotype 1 Infection Gastroenterology 146, 420-429
-
(2014)
Gastroenterology
, vol.146
, pp. 420-429
-
-
Everson, G.T.1
Sims, K.D.2
Rodriguez-Torres, M.3
Hézode, C.4
Lawitz, E.5
Bourliere, M.6
Loustaud-Ratti, V.7
Rustgi, V.8
Schwartz, H.9
Tatum, H.10
Marcellin, P.11
Pol, S.12
Thuluvath, P.J.13
Eley, T.14
Wang, X.15
Huang, S.-P.16
McPhee, F.17
Wind-Rotolo, M.18
Chung, E.19
Pasquinelli, C.20
Grasela, D.M.21
Gardiner, D.F.22
more..
-
21
-
-
80052073390
-
Molecular mechanisms of viral and host cell substrate recognition by hepatitis C virus NS3/4A protease
-
Romano, K. P., Laine, J. M., Deveau, L. M., Cao, H., Massi, F., and Schiffer, C. A. (2011) Molecular mechanisms of viral and host cell substrate recognition by hepatitis C virus NS3/4A protease J. Virol. 85, 6106-6116
-
(2011)
J. Virol.
, vol.85
, pp. 6106-6116
-
-
Romano, K.P.1
Laine, J.M.2
Deveau, L.M.3
Cao, H.4
Massi, F.5
Schiffer, C.A.6
-
22
-
-
84864602817
-
The molecular basis of drug resistance against hepatitis C virus NS3/4A protease inhibitors
-
Romano, K. P., Ali, A., Aydin, C., Soumana, D., Ozen, A., Deveau, L. M., Silver, C., Cao, H., Newton, A., Petropoulos, C. J., Huang, W., and Schiffer, C. A. (2012) The molecular basis of drug resistance against hepatitis C virus NS3/4A protease inhibitors PLoS Pathog. 8, e1002832
-
(2012)
PLoS Pathog.
, vol.8
, pp. 1002832
-
-
Romano, K.P.1
Ali, A.2
Aydin, C.3
Soumana, D.4
Ozen, A.5
Deveau, L.M.6
Silver, C.7
Cao, H.8
Newton, A.9
Petropoulos, C.J.10
Huang, W.11
Schiffer, C.A.12
-
23
-
-
84865563661
-
Vaniprevir with pegylated interferon alpha-2a and ribavirin in treatment-naieve patients with chronic hepatitis C: A randomized phase II study
-
MK-7009 Protocol 007 Study Group. ()
-
Manns, M. P., Gane, E., Rodriguez-Torres, M., Stoehr, A., Yeh, C.-T., Marcellin, P., Wiedmann, R. T., Hwang, P. M., Caro, L., Barnard, R. J. O., Lee, A. W., and MK-7009 Protocol 007 Study Group. (2012) Vaniprevir with pegylated interferon alpha-2a and ribavirin in treatment-naieve patients with chronic hepatitis C: A randomized phase II study Hepatology 56, 884-893
-
(2012)
Hepatology
, vol.56
, pp. 884-893
-
-
Manns, M.P.1
Gane, E.2
Rodriguez-Torres, M.3
Stoehr, A.4
Yeh, C.-T.5
Marcellin, P.6
Wiedmann, R.T.7
Hwang, P.M.8
Caro, L.9
Barnard, R.J.O.10
Lee, A.W.11
-
24
-
-
79953224799
-
Potency, safety, and pharmacokinetics of the NS3/4A protease inhibitor BI201335 in patients with chronic HCV genotype-1 infection
-
Manns, M. P., Bourlieare, M., Benhamou, Y., Pol, S., Bonacini, M., Trepo, C., Wright, D., Berg, T., Calleja, J. L., White, P. W., Stern, J. O., Steinmann, G., Yong, C.-L., Kukolj, G., Scherer, J., and Boecher, W. O. (2011) Potency, safety, and pharmacokinetics of the NS3/4A protease inhibitor BI201335 in patients with chronic HCV genotype-1 infection J. Hepatol. 54, 1114-1122
-
(2011)
J. Hepatol.
, vol.54
, pp. 1114-1122
-
-
Manns, M.P.1
Bourliere, M.2
Benhamou, Y.3
Pol, S.4
Bonacini, M.5
Trepo, C.6
Wright, D.7
Berg, T.8
Calleja, J.L.9
White, P.W.10
Stern, J.O.11
Steinmann, G.12
Yong, C.-L.13
Kukolj, G.14
Scherer, J.15
Boecher, W.O.16
-
25
-
-
84866309379
-
Abundant drug-resistant NS3 mutants detected by deep sequencing in hepatitis C virus-infected patients undergoing NS3 protease inhibitor monotherapy
-
Svarovskaia, E. S., Martin, R., McHutchison, J. G., Miller, M. D., and Mo, H. (2012) Abundant drug-resistant NS3 mutants detected by deep sequencing in hepatitis C virus-infected patients undergoing NS3 protease inhibitor monotherapy J. Clin. Microbiol. 50, 3267-3274
-
(2012)
J. Clin. Microbiol.
, vol.50
, pp. 3267-3274
-
-
Svarovskaia, E.S.1
Martin, R.2
McHutchison, J.G.3
Miller, M.D.4
Mo, H.5
-
26
-
-
84863663083
-
HCV genotypes are differently prone to the development of resistance to linear and macrocyclic protease inhibitors
-
Cento, V., Mirabelli, C., Salpini, R., Dimonte, S., Artese, A., Costa, G., Mercurio, F., Svicher, V., Parrotta, L., Bertoli, A., Ciotti, M., Di Paolo, D., Sarrecchia, C., Andreoni, M., Alcaro, S., Angelico, M., Perno, C. F., and Ceccherini-Silberstein, F. (2012) HCV genotypes are differently prone to the development of resistance to linear and macrocyclic protease inhibitors PLoS One 7, e39652
-
(2012)
PLoS One
, vol.7
, pp. 39652
-
-
Cento, V.1
Mirabelli, C.2
Salpini, R.3
Dimonte, S.4
Artese, A.5
Costa, G.6
Mercurio, F.7
Svicher, V.8
Parrotta, L.9
Bertoli, A.10
Ciotti, M.11
Di Paolo, D.12
Sarrecchia, C.13
Andreoni, M.14
Alcaro, S.15
Angelico, M.16
Perno, C.F.17
Ceccherini-Silberstein, F.18
-
27
-
-
84896292745
-
The discovery of asunaprevir (BMS-650032), an orally efficacious NS3 protease inhibitor for the treatment of hepatitis C virus infection
-
Scola, P. M., Sun, L. Q., Wang, A. X., Chen, J., Sin, N., Venables, B. L., Sit, S. Y., Chen, Y., Cocuzza, A., Bilder, D. M., D'Andrea, S. V., Zheng, B., Hewawasam, P., Tu, Y., Friborg, J., Falk, P., Hernandez, D., Levine, S., Chen, C., Yu, F., Sheaffer, A. K., Zhai, G., Barry, D., Knipe, J. O., Han, Y. H., Schartman, R., Donoso, M., Mosure, K., Sinz, M. W., Zvyaga, T., Good, A. C., Rajamani, R., Kish, K., Tredup, J., Klei, H. E., Gao, Q., Mueller, L., Colonno, R. J., Grasela, D. M., Adams, S. P., Loy, J., Levesque, P. C., Sun, H., Shi, H., Sun, L., Warner, W., Li, D., Zhu, J., Meanwell, N. A., and McPhee, F. (2014) The discovery of asunaprevir (BMS-650032), an orally efficacious NS3 protease inhibitor for the treatment of hepatitis C virus infection J. Med. Chem. 57, 1730-1752
-
(2014)
J. Med. Chem.
, vol.57
, pp. 1730-1752
-
-
Scola, P.M.1
Sun, L.Q.2
Wang, A.X.3
Chen, J.4
Sin, N.5
Venables, B.L.6
Sit, S.Y.7
Chen, Y.8
Cocuzza, A.9
Bilder, D.M.10
Dandrea, S.V.11
Zheng, B.12
Hewawasam, P.13
Tu, Y.14
Friborg, J.15
Falk, P.16
Hernandez, D.17
Levine, S.18
Chen, C.19
Yu, F.20
Sheaffer, A.K.21
Zhai, G.22
Barry, D.23
Knipe, J.O.24
Han, Y.H.25
Schartman, R.26
Donoso, M.27
Mosure, K.28
Sinz, M.W.29
Zvyaga, T.30
Good, A.C.31
Rajamani, R.32
Kish, K.33
Tredup, J.34
Klei, H.E.35
Gao, Q.36
Mueller, L.37
Colonno, R.J.38
Grasela, D.M.39
Adams, S.P.40
Loy, J.41
Levesque, P.C.42
Sun, H.43
Shi, H.44
Sun, L.45
Warner, W.46
Li, D.47
Zhu, J.48
Meanwell, N.A.49
McPhee, F.50
more..
-
28
-
-
84890495645
-
Improving the resistance profile of hepatitis C NS3/4A inhibitors: Dynamic substrate envelope guided design
-
Oezen, A., Sherman, W., and Schiffer, C. A. (2013) Improving the resistance profile of hepatitis C NS3/4A inhibitors: Dynamic substrate envelope guided design J. Chem. Theory Comput. 9, 5693-5705
-
(2013)
J. Chem. Theory Comput.
, vol.9
, pp. 5693-5705
-
-
Oezen, A.1
Sherman, W.2
Schiffer, C.A.3
-
29
-
-
33645227102
-
Mechanism of substrate recognition by drug-resistant human immunodeficiency virus type 1 protease variants revealed by a novel structural intermediate
-
Prabu-Jeyabalan, M., Nalivaika, E. A., Romano, K., and Schiffer, C. A. (2006) Mechanism of substrate recognition by drug-resistant human immunodeficiency virus type 1 protease variants revealed by a novel structural intermediate J. Virol. 80, 3607-3616
-
(2006)
J. Virol.
, vol.80
, pp. 3607-3616
-
-
Prabu-Jeyabalan, M.1
Nalivaika, E.A.2
Romano, K.3
Schiffer, C.A.4
|