Reactivation of dormant "non-culturable" Mycobacterium tuberculosis developed invitro after injection in mice: Both the dormancy depth and host genetics influence the outcome

Microbial Pathogenesis

Volumn 78, Issue , 2015, Pages 63-66

  Shleeva, Margarita ^a   Kondratieva, Tatiana ^b   Rubakova, Elvira ^b   Vostroknutova, Galina ^a   Kaprelyants, Arseny ^a   Apt, Alexander ^b  

^a BACH INSTITUTE OF BIOCHEMISTRY   (Russian Federation)

^b CENTRAL TUBERCULOSIS RESEARCH INSTITUTE   (Russian Federation)

Author keywords

Inbred mouse strains; Latency; Reactivation; Tuberculosis

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL GENETICS; BACTERIAL GROWTH; BACTERIAL STRAIN; BACTERIUM COLONY; BACTERIUM CULTURE; CONTROLLED STUDY; DISEASE PREDISPOSITION; DORMANCY; FEMALE; GENETIC SUSCEPTIBILITY; HOST PATHOGEN INTERACTION; IN VITRO STUDY; LATENT TUBERCULOSIS; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; POSTPRIMARY TUBERCULOSIS; STRAIN DIFFERENCE; ANIMAL; C57BL MOUSE; GENETIC PREDISPOSITION; GENETICS; GROWTH, DEVELOPMENT AND AGING; HUMAN; MICROBIOLOGY; PHYSIOLOGY; TUBERCULOSIS;

CORYNEBACTERINEAE; MUS; MYCOBACTERIUM TUBERCULOSIS;

ANIMALS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HOST-PATHOGEN INTERACTIONS; HUMANS; MICE; MICE, INBRED C57BL; MYCOBACTERIUM TUBERCULOSIS; TUBERCULOSIS;

EID: 84914165743     PISSN: 08824010     EISSN: 10961208     Source Type: Journal    
DOI: 10.1016/j.micpath.2014.11.016     Document Type: Article

References (19)

1. Barry C.E., Boshoff H.I., Dartois V., Dick T., Ehrt S., Flynn J., et al. The spectrum of latent tuberculosis: rethinking the biology and intervention strategies. Nat. Rev. Microbiol. 2009, 7:845-855.
2. Chao M.C., Rubin E.J. Letting sleeping dos lie: does dormancy play a role in tuberculosis?. Annu Rev. Microbiol. 2010, 64:293-311.
3. Lillebaek T., Andersen A.B., Dirksen A., Smith E., Skovgaard L.T., Kok-Jensen A. Persistent high incidence of tuberculosis in immigrants in a low-incidence country. Emerg. Infect. Dis. 2002, 8:679-684.
4. Ottenhoff T.H., Kaufmann S.H. Vaccines against tuberculosis: where are we and where do we need to go?. PLoS Pathog. 2012, 8:e1002607.
5. Kell D.B., Mukamolova G.V., Finan C.L., Zhao H., Goodacre R., et al. Resuscitation of "uncultured" microorganisms. Microbial Biodiversity and Bioprospecting 2004, 100-108. ASM Press, Washington, DC.
6. Medlar E.M., Bernstein S., Steward D.M. Abacteriologic study of resected tuberculous lesions. Am. Rev. Tuberc. 1952, 66:36-43.
7. Biketov S., Mukamolova G.V., Potapov V., Gilenkov E., Vostroknutova G., et al. Culturability of Mycobacterium tuberculosis cells isolated from murine macrophages: a bacterial growth factor promotes recovery. FEMS Immunol. Med. Microbiol. 2000, 29:233-240.
8. Dhillon J., Lowrie D.B., Mitchison D.A. Mycobacterium tuberculosis from chronic murine infections that grows in liquid but not on solid medium. BMC Infect. Dis. 2004, 4:51-55.
9. Shleeva M.O., Bagramyan K., Telkov M.V., Mukamolova G.V., Young M., et al. Formation and resuscitation of 'non-culturable' cells of Rhodococcus rhodochrous and Mycobacterium tuberculosis in prolonged stationary phase. Microbiology 2002, 148:1581-1591.
10. Shleeva M.O., Kudykina YuK., Vostroknutova G.N., Suzina N.E., Kaprelyants A.S. Dormant ovoid cells of Mycobacterium tuberculosis formed in response to gradual external acidification. Tuberc. (Edinb.) 2011, 91:146-154.
11. Khomenko A.G., Golyshevskaya V.I. Filterable forms of mycobacterium tuberculosis. ZErkrank Atm-Org 1984, 162:14754.
12. Shleeva M., Goncharenko A., Kudykina Yu, Young D., Young M., Kaprelyants A. Cyclic AMP dependent resuscitation of dormant mycobacteria by exogenous free fatty acids. PLoS One 2013, 8:e82914.
13. Kondratieva T., Azhikina T., Nikonenko B., Kaprelyants A., Apt A. Latent tuberculosis infection: what we know about its genetic control?. Tuberc. (Edinb.) 2014, 94:462-468.
14. Kondratieva E., Logunova N., Majorov K., Averbakh M., Apt A. Host genetics in granuloma formation: human-like lung pathology in mice with reciprocal genetic susceptibility to M. tuberculosis and M. avium. PLoS One 2010, 5:e10515.
15. Connell N.D. Mycobacterium: isolation, maintenance, transformation, and mutant selection. Methods Cell. Biol. 1994, 45. 107e25.
16. Stevenson M.M., Kondratieva T.K., Apt A.S., Tam M.F., Skamene E. Invitro and invivo T cell responses in mice during bronchopulmonary infection with mucoid Pseudomonas aeruginosa. Clin. Exp. Immunol. 1995, 99:98-103.
17. Eruslanov E.B., Majorov K.B., Orlova M.O., Mischenko V.V., Kondratieva T.K., et al. Lung cell responses to M.tuberculosis in genetically susceptible and resistant mice following intratracheal challenge. Clin. Exp. Immunol. 2004, 135:19-28.
18. Woolhiser L., Tamayo M.H., Wang B., Gruppo V., Belisle J.T., et al. Invivo adaptation of the wayne model of latent tuberculosis. Infect. Immun. 2007, 75:2621-2625.
19. Mukamolova G.V., Kaprelyants A.S., Kell D.B., Young M. Adoption of the transiently non-culturable state - a bacterial survival strategy?. Adv. Microb. Physiol. 2003, 47. 65e129.