Simvastatin Pretreatment Protects Cerebrum from Neuronal Injury by Decreasing the Expressions of Phosphor-CaMK II and AQP4 in Ischemic Stroke Rats

Journal of Molecular Neuroscience

Volumn 54, Issue 4, 2014, Pages 591-601

  Zhu, Min xia ^a,b   Lu, Chao ^b   Xia, Chun mei ^b   Qiao, Zhong wei ^b   Zhu, Da nian ^b  

^a XIZANG MINZU UNIVERSITY   (China)

^b FUDAN UNIVERSITY   (China)

Author keywords

Aquaporin 4; Ca2+ calmodulin dependent protein kinase II; Cytotoxic edema; Excitotoxicity; NR3A; Simvastatin

Indexed keywords

AQUAPORIN 4; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CHOLESTEROL; CHOLESTEROL ESTER; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; PROTEIN BAX; PROTEIN BCL 2; SIMVASTATIN; ANTILIPEMIC AGENT; AQP4 PROTEIN, RAT; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NR3A NMDA RECEPTOR; PROTEIN BINDING;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIGEN ANTIBODY COMPLEX; ARTICLE; BRAIN EDEMA; BRAIN ISCHEMIA; BRAIN WATER; CHOLESTEROL BLOOD LEVEL; ENZYME PHOSPHORYLATION; EXCITOTOXICITY; HIPPOCAMPAL CA1 REGION; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROPROTECTION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RAT; REPERFUSION INJURY; WATER CONTENT; WESTERN BLOTTING; ANIMAL; BRAIN; CYTOLOGY; DOWN REGULATION; DRUG EFFECTS; GENETICS; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; METABOLISM; NERVE CELL; SPRAGUE DAWLEY RAT;

RATTUS;

ANIMALS; AQUAPORIN 4; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CEREBRUM; CHOLESTEROL; DOWN-REGULATION; HYPOLIPIDEMIC AGENTS; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; NEURONS; PROTEIN BINDING; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, N-METHYL-D-ASPARTATE; SIMVASTATIN;

EID: 84914163138     PISSN: 08958696     EISSN: 15591166     Source Type: Journal    
DOI: 10.1007/s12031-014-0307-6     Document Type: Article

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