Structure of the meningococcal vaccine antigen nada and epitope mapping of a bactericidal antibody

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 48, 2014, Pages 17128-17133

  Malito, Enrico ^a   Biancucci, Marco ^a,c   Faleri, Agnese ^a   Ferlenghi, Ilaria ^a   Scarselli, Maria ^a   Maruggi, Giulietta ^a   Surdo, Paola Lo ^a   Veggi, Daniele ^a   Liguori, Alessia ^a   Santini, Laura ^a   Bertoldi, Isabella ^a   Petracca, Roberto ^a   Marchi, Sara ^a   Romagnoli, Giacomo ^a   Cartocci, Elena ^a   Vercellino, Irene ^a,d   Savino, Silvana ^a   Spraggon, Glen ^b   Norais, Nathalie ^a   Pizza, Mariagrazia ^a   Rappuoli, Rino ^a   Masignani, Vega ^a   Bottomley, Matthew James ^a   more..

^a NOVARTIS VACCINES AND DIAGNOSTICS   (Italy)

^b Genomic Institute of the Novetis Foundation   (United States)

^c NORTHWESTERN UNIVERSITY   (United States)

^d PAUL SCHERRER INSTITUTE   (Switzerland)

Author keywords

Coiled coil; Hydrogen deuterium exchange; Meningitis; Thermostability; Trimeric autotransporter adhesin

Indexed keywords

NEISSERIA MENINGITIDIS;

ADHESIN; BACTERIAL ANTIGEN; BACTERIUM ANTIBODY; ISOPROTEIN; MENINGOCOCCUS VACCINE; NADA PROTEIN, NEISSERIA MENINGITIDIS;

AMINO ACID SEQUENCE; ANTIBODY COMBINING SITE; CHEMICAL STRUCTURE; CHEMISTRY; DEUTERIUM HYDROGEN EXCHANGE; ELECTROSPRAY MASS SPECTROMETRY; EPITOPE MAPPING; GENETICS; IMMUNOLOGY; MOLECULAR GENETICS; NEISSERIA MENINGITIDIS; PROCEDURES; PROTEIN MULTIMERIZATION; PROTEIN STABILITY; PROTEIN TERTIARY STRUCTURE; SEQUENCE HOMOLOGY; TEMPERATURE; TRANSMISSION ELECTRON MICROSCOPY; X RAY CRYSTALLOGRAPHY;

ADHESINS, BACTERIAL; AMINO ACID SEQUENCE; ANTIBODIES, BACTERIAL; ANTIGENS, BACTERIAL; BINDING SITES, ANTIBODY; CRYSTALLOGRAPHY, X-RAY; DEUTERIUM EXCHANGE MEASUREMENT; EPITOPE MAPPING; MENINGOCOCCAL VACCINES; MICROSCOPY, ELECTRON, TRANSMISSION; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NEISSERIA MENINGITIDIS, SEROGROUP B; PROTEIN ISOFORMS; PROTEIN MULTIMERIZATION; PROTEIN STABILITY; PROTEIN STRUCTURE, TERTIARY; SEQUENCE HOMOLOGY, AMINO ACID; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TEMPERATURE;

EID: 84914162420     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1419686111     Document Type: Review

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