Glia maturation factor-γ phosphorylation at tyr-104 regulates actin dynamics and contraction in human airway smooth muscle

American Journal of Respiratory Cell and Molecular Biology

Volumn 51, Issue 5, 2014, Pages 652-659

  Wang, Tao ^a   Cleary, Rachel A ^a   Wang, Ruping ^a   Tang, Dale D ^a  

^a ALBANY MEDICAL COLLEGE   (United States)

Author keywords

Actin polymerization; Actin associated protein; Signal transduction; Tyrosine kinase

Indexed keywords

ABELSON KINASE; ACETYLCHOLINE; ACTIN; ACTIN RELATED PROTEIN 2; ACTR2 PROTEIN, HUMAN; CHOLINERGIC RECEPTOR STIMULATING AGENT; GLIA MATURATION FACTOR; GLIA MATURATION FACTOR GAMMA; PROTEIN TYROSINE KINASE; TYROSINE;

CELL CULTURE; CYTOLOGY; DRUG EFFECTS; HUMAN; METABOLISM; MUSCLE CONTRACTION; PHOSPHORYLATION; PHYSIOLOGY; RESPIRATORY SYSTEM; SIGNAL TRANSDUCTION; SMOOTH MUSCLE; SMOOTH MUSCLE FIBER;

ACETYLCHOLINE; ACTIN-RELATED PROTEIN 2; ACTINS; CELLS, CULTURED; CHOLINERGIC AGONISTS; GLIA MATURATION FACTOR; HUMANS; MUSCLE CONTRACTION; MUSCLE, SMOOTH; MYOCYTES, SMOOTH MUSCLE; PHOSPHORYLATION; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS C-ABL; RESPIRATORY SYSTEM; SIGNAL TRANSDUCTION; TYROSINE;

EID: 84914118536     PISSN: 10441549     EISSN: 15354989     Source Type: Journal    
DOI: 10.1165/rcmb.2014-0125OC     Document Type: Article

References (41)

1. Gao N, Huang J, He W, Zhu M, Kamm KE, Stull JT. Signaling through myosin light chain kinase in smooth muscles. J Biol Chem 2013;288:7596-7605.
2. Somlyo AV, Khromov AS, Webb MR, Ferenczi MA, Trentham DR, He ZH, Sheng S, Shao Z, Somlyo AP. Smooth muscle myosin: regulation and properties. Philos Trans R Soc Lond B Biol Sci 2004;359:1921-1930.
3. Gunst SJ, Zhang W. Actin cytoskeletal dynamics in smooth muscle: a new paradigm for the regulation of smooth muscle contraction. Am J Physiol Cell Physiol 2008;295:C576-C587.
4. Kim HR, Gallant C, Leavis PC, Gunst SJ, Morgan KG. Cytoskeletal remodeling in differentiated vascular smooth muscle is actin isoform dependent and stimulus dependent. Am J Physiol Cell Physiol 2008;295:C768-C778.
5. Rembold CM, Tejani AD, Ripley ML, Han S. Paxillin phosphorylation, actin polymerization, noise temperature, and the sustained phase of swine carotid artery contraction. Am J Physiol Cell Physiol 2007;293:C993-C1002.
6. Tang DD, Anfinogenova Y. Physiologic properties and regulation of the actin cytoskeleton in vascular smooth muscle. J Cardiovasc Pharmacol Ther 2008;13:130-140.
7. Wang T, Cleary RA, Wang R, Tang DD. Role of the adapter protein abi1 in actin-associated signaling and smooth muscle contraction. J Biol Chem 2013;288:20713-20722.
8. Anfinogenova Y, Wang R, Li QF, Spinelli AM, Tang DD. Abl silencing inhibits cas-mediated process and constriction in resistance arteries. Circ Res 2007;101:420-428.
9. Walsh MP, Cole WC. The role of actin filament dynamics in the myogenic response of cerebral resistance arteries. J Cereb Blood Flow Metab 2013;33:1-12.
10. Pollard TD. Regulation of actin filament assembly by arp2/3 complex and formins. Annu Rev Biophys Biomol Struct 2007;36:451-477.
11. Lapetina S, Mader CC, Machida K, Mayer BJ, Koleske AJ. Arg interacts with cortactin to promote adhesion-dependent cell edge protrusion. J Cell Biol 2009;185:503-519.
12. Tang DD. P130 crk-associated substrate (cas) in vascular smooth muscle. J Cardiovasc Pharmacol Ther 2009;14:89-98.
13. Wang R, Mercaitis OP, Jia L, Panettieri RA, Tang DD. Raf-1, actin dynamics and abl in human airway smooth muscle cells. Am J Respir Cell Mol Biol 2013;48:172-178.
14. Gandhi M, Smith BA, Bovellan M, Paavilainen V, Daugherty-Clarke K, Gelles J, Lappalainen P, Goode BL. Gmf is a cofilin homolog that binds arp2/3 complex to stimulate filament debranching and inhibit actin nucleation. Curr Biol 2010;20:861-867.
15. Ydenberg CA, Padrick SB, Sweeney MO, Gandhi M, Sokolova O, Goode BL. Gmf severs actin-arp2/3 complex branch junctions by a cofilin-like mechanism. Curr Biol 2013;23:1037-1045.
16. Poukkula M, Kremneva E, Serlachius M, Lappalainen P. Actindepolymerizing factor homology domain: a conserved fold performing diverse roles in cytoskeletal dynamics. Cytoskeleton 2011;68:471-490.
17. Jia L, Wang R, Tang DD. Abl regulates smooth muscle cell proliferation by modulating actin dynamics and erk1/2 activation. Am J Physiol Cell Physiol 2012;302:C1026-C1034.
18. Qiu Z, Cang Y, Goff SP. C-abl tyrosine kinase regulates cardiac growth and development. Proc Natl Acad Sci USA 2010;107:1136-1141.
19. Hu H, Bliss JM, Wang Y, Colicelli J. Rin1 is an abl tyrosine kinase activator and a regulator of epithelial-cell adhesion and migration. Curr Biol 2005;15:815-823.
20. Jia L, Tang DD. Abl activation regulates the dissociation of cas from cytoskeletal vimentin by modulating cas phosphorylation in smooth muscle. Am J Physiol Cell Physiol 2010;299:C630-C637.
21. Chen S, Wang R, Li QF, Tang DD. Abl knockout differentially affects p130 crk-associated substrate, vinculin, and paxillin in blood vessels of mice. Am J Physiol Heart Circ Physiol 2009;297:H533-H539.
22. Chen S, Tang DD. C-abl tyrosine kinase regulates cytokinesis of human airway smoothmuscle cells. AmJ Respir CellMol Biol 2014;50:1076-1083.
23. Li QF, Spinelli AM, Wang R, Anfinogenova Y, Singer HA, Tang DD. Critical role of vimentin phosphorylation at ser-56 by p21-activated kinase in vimentin cytoskeleton signaling. J Biol Chem 2006;281:34716-34724.
24. Tang DD, Bai Y, Gunst SJ. Silencing of p21-activated kinase attenuates vimentin phosphorylation on ser-56 and reorientation of the vimentin network during stimulation of smooth muscle cells by 5-hydroxytryptamine. Biochem J 2005;388:773-783.
25. Wang R, Li QF, Anfinogenova Y, Tang DD. Dissociation of crkassociated substrate from the vimentin network is regulated by p21-activated kinase on ach activation of airway smooth muscle. Am J Physiol Lung Cell Mol Physiol 2007;292:L240-L248.
26. Wang R, Li Q, Tang DD. Role of vimentin in smooth muscle force development.-Am J Physiol Cell Physiol 2006;291:C483-C489.
27. Wang JY. Controlling abl: auto-inhibition and co-inhibition? Nat Cell Biol 2004;6:3-7.
28. Burton EA, Oliver TN, Pendergast AM. Abl kinases regulate actin comet tail elongation via an n-wasp-dependent pathway. Mol Cell Biol 2005;25:8834-8843.
29. Huang YL, Zhang WW, Gunst SJ. Activation of vinculin induced by cholinergic stimulation regulates contraction of tracheal smooth muscle tissue. J Biol Chem 2011;286:3630-3644.
30. Zhao R, Du L, Huang Y, Wu Y, Gunst SJ. Actin depolymerization factor/ cofilin activation regulates actin polymerization and tension development in canine tracheal smooth muscle. J Biol Chem2008;283:36522-36531.
31. Luan Q, Nolen BJ. Structural basis for regulation of arp2/3 complex by gmf. Nat Struct Mol Biol 2013;20:1062-1068.
32. Gerthoffer WT. Actin cytoskeletal dynamics in smooth muscle contraction. Can J Physiol Pharmacol 2005;83:851-856.
33. Thomson DM, Ascione MP, Grange J, Nelson C, Hansen MD. Phosphorylation of vasp by ampk alters actin binding and occurs at a novel site. Biochem Biophys Res Commun 2011;414:215-219.
34. Pollard TD, Borisy GG. Cellular motility driven by assembly and disassembly of actin filaments. Cell 2003;112:453-465.
35. Gunst SJ, Tang DD. The contractile apparatus and mechanical properties of airway smooth muscle. Eur Respir J 2000;15:600-616.
36. Gerthoffer WT, Gunst SJ. Invited review: focal adhesion and small heat shock proteins in the regulation of actin remodeling and contractility in smooth muscle. J Appl Physiol 2001;91:963-972.
37. Herrera AM, Martinez EC, Seow CY. Electron microscopic study of actin polymerization in airway smooth muscle. Am J Physiol Lung Cell Mol Physiol 2004;286:L1161-L1168.
38. Amrani Y, Tliba O, Deshpande DA, Walseth TF, Kannan MS, Panettieri RA Jr. Bronchial hyperresponsiveness: insights into new signaling molecules. Curr Opin Pharmacol 2004;4:230-234.
39. Tliba O, Deshpande D, Chen H, Van BC, Kannan M, Panettieri RA Jr, Amrani Y. Il-13 enhances agonist-evoked calcium signals and contractile responses in airway smoothmuscle. Br J Pharmacol 2003;140:1159-1162.
40. Deshpande DA, Dogan S, Walseth TF, Miller SM, Amrani Y, Panettieri RA, Kannan MS. Modulation of calcium signaling by interleukin-13 in human airway smooth muscle: role of cd38/cyclic adenosine diphosphate ribose pathway. Am J Respir Cell Mol Biol 2004;31:36-42.
41. Cleary RA, Wang R, Wang T, Tang DD. Role of abl in airway hyperresponsiveness and airway remodeling. Respir Res 2013;14:105.