Loss of α(E)-catenin potentiates cisplatin-induced nephrotoxicity via increasing apoptosis in renal tubular epithelial cells

Toxicological Sciences

Volumn 141, Issue 1, 2014, Pages 254-262

  Wang, Xinhui ^a   Grunz Borgmann, Elizabeth A ^a   Parrish, Alan R ^a  

^a UNIVERSITY OF MISSOURI   (United States)

Author keywords

Aging; AKI; Apoptosis; Cisplatin; Catenin

Indexed keywords

ALPHA CATENIN; CASPASE 3; CASPASE 7; CASPASE INHIBITOR; CISPLATIN; CREATININE; LACTATE DEHYDROGENASE; ANTINEOPLASTIC AGENT;

APOPTOSIS; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CREATININE BLOOD LEVEL; ENZYME ACTIVATION; GENE SILENCING; IN VIVO STUDY; KIDNEY TUBULE CELL; NEPHROTOXICITY; NONHUMAN; PROTEIN CLEAVAGE; PROTEIN DEPLETION; PROTEIN EXPRESSION; RAT; AGING; ANIMAL; CELL CULTURE TECHNIQUE; CELL LINE; CELL SURVIVAL; CHEMICALLY INDUCED; DRUG EFFECTS; EPITHELIUM CELL; FISCHER 344 RAT; GENETICS; KIDNEY DISEASE; KIDNEY PROXIMAL TUBULE; MALE; METABOLISM; PATHOLOGY; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

AGING; ALPHA CATENIN; ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BLOTTING, WESTERN; CELL CULTURE TECHNIQUES; CELL LINE; CELL SURVIVAL; CISPLATIN; EPITHELIAL CELLS; GENE KNOCKDOWN TECHNIQUES; KIDNEY DISEASES; KIDNEY TUBULES, PROXIMAL; MALE; RATS, INBRED F344; REAL-TIME POLYMERASE CHAIN REACTION;

EID: 84913612688     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfu130     Document Type: Article

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