Clinical application of inert gas Multiple Breath Washout in children and adolescents with asthma

Respiratory Medicine

Volumn 108, Issue 9, 2014, Pages 1254-1259

  Zwitserloot, Annelies ^a,b   Fuchs, Susanne I ^a   Müller, Christina ^a   Bisdorf, Kornelia ^a   Gappa, Monika ^a  

^a MARIEN HOSPITAL WESEL   (Germany)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Asthma; Breath; Children; Multiple; SF6; Ultrasonic flow sensor; Washout

Indexed keywords

INERT GAS; SALBUTAMOL; SULFUR HEXAFLUORIDE; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; BRONCHODILATING AGENT;

ARTICLE; ASTHMA; CHILD; CLINICAL ARTICLE; CLINICAL ASSESSMENT TOOL; CONTROLLED STUDY; FEMALE; FORCED EXPIRATORY VOLUME; HUMAN; LUNG CLEARANCE INDEX; MALE; MULTIPLE BREATH WASHOUT; OUTPATIENT DEPARTMENT; PATIENT SELECTION; PILOT STUDY; PRESCHOOL CHILD; SPIROMETRY; ADOLESCENT; BREATH ANALYSIS; CASE CONTROL STUDY; CROSS-SECTIONAL STUDY; DRUG EFFECTS; PATHOPHYSIOLOGY; PHYSIOLOGY; PROCEDURES; YOUNG ADULT;

ADOLESCENT; ADRENERGIC BETA-2 RECEPTOR AGONISTS; ALBUTEROL; ASTHMA; BREATH TESTS; BRONCHODILATOR AGENTS; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; CROSS-SECTIONAL STUDIES; FEMALE; FORCED EXPIRATORY VOLUME; HUMANS; MALE; PILOT PROJECTS; SPIROMETRY; YOUNG ADULT;

EID: 84913610883     PISSN: 09546111     EISSN: 15323064     Source Type: Journal    
DOI: 10.1016/j.rmed.2014.07.003     Document Type: Article

References (22)

1. M. Dolhnikoff, L.F. da Silva, and B.B. de Araujo The outer wall of small airways is a major site of remodeling in fatal asthma J Allergy Clin Immunol 123 5 2009 1090 1097 1097
2. Q. Hamid, Y. Song, and T.C. Kotsimbos Inflammation of small airways in asthma J Allergy Clin Immunol 100 1 1997 44 51
3. J.R. Johnson, and Q. Hamid Appraising the small airways in asthma Curr Opin Pulm Med 18 1 2012 23 28
4. S. Saglani, D.N. Payne, and J. Zhu Early detection of airway wall remodeling and eosinophilic inflammation in preschool wheezers Am J Respir Crit Care Med 176 9 2007 858 864
5. From the global strategy for asthma management and prevention 2012 Global Initiative for Asthma (GINA) Available from: http://www.ginasthma.org/
6. L.B. Bacharier, R.C. Strunk, and D. Mauger Classifying asthma severity in children: mismatch between symptoms, medication use, and lung function Am J Respir Crit Care Med 170 4 2004 426 432
7. A. Horsley Lung clearance index in the assessment of airways disease Respir Med 103 6 2009 793 799
8. P.T. Macklem The physiology of small airways Am J Respir Crit Care Med 157 5 Pt 2 1998 S181 S183
9. H. Ellemunter, S.I. Fuchs, and K.M. Unsinn Sensitivity of lung clearance index and chest computed tomography in early CF lung disease Respir Med 104 12 2010 1834 1842
10. P.M. Gustafsson Peripheral airway involvement in CF and asthma compared by inert gas washout Pediatr Pulmonol 42 2 2007 168 176
11. C. Keen, A.C. Olin, and G. Wennergren Small airway function, exhaled NO and airway hyper-responsiveness in paediatric asthma Respir Med 105 10 2011 1476 1484
12. K.A. Macleod, A.R. Horsley, and N.J. Bell Ventilation heterogeneity in children with well controlled asthma with normal spirometry indicates residual airways disease Thorax 64 1 2009 33 37
13. S. Sonnappa, C.M. Bastardo, and A. Wade Repeatability and bronchodilator reversibility of lung function in young children Eur Respir J 38 6 2011 Dec 1431 1436
14. S. Sonnappa, C.M. Bastardo, and A. Wade Symptom-pattern phenotype and pulmonary function in preschool wheezers J Allergy Clin Immunol 126 3 2010 519 526
15. S.I. Fuchs, C. Buess, and S. Lum Multiple breath washout with a sidestream ultrasonic flow sensor and mass spectrometry: a comparative study Pediatr Pulmonol 41 12 2006 1218 1225
16. S.I. Fuchs, J. Eder, and H. Ellemunter Lung clearance index: normal values, repeatability, and reproducibility in healthy children and adolescents Pediatr Pulmonol 44 12 2009 1180 1185
17. M.R. Miller, J. Hankinson, and V. Brusaco Standardisation of spirometry Eur Respir J 26 2 2005 319 338
18. S.I. Fuchs, and M. Gappa Equipment for multiple breath washout Eur Respir J 35 2 2010 458 459
19. R.C. Strunk, S.J. Szefler, and B.R. Phillips Relationship of exhaled nitric oxide to clinical and inflammatory markers of persistent asthma in children J Allergy Clin Immunol 112 5 2003 883 892
20. P.H. Quanjer, S. Stanojevic, and T.J. Cole Multi-ethnic reference values for spirometry for the 3-95 yr age range: the global lung function 2012 equations Eur Respir J 40 6 2012 1324 1343
21. M. Verini, N. Rossi, and T. Dalfino Lack of correlation between clinical patterns of asthma and airway obstruction Allergy Asthma Proc 22 5 2001 297 302
22. G. Kaik Onset of action and maximum effect of bronchodilators administered by a metered dose inhaler. Clinical investigations with fenoterol, hexoprenaline and terbutaline (author's transl) Wien Klin Wochenschr 88 20 1976 674 679