Simplification of antiviral hepatitis C virus therapy to support expanded access in resource-limited settings

Journal of Hepatology

Volumn 61, Issue 1, 2014, Pages S132-S138

  Ford, Nathan ^a   Swan, Tracy ^b   Beyer, Peter ^a   Hirnschall, Gottfried ^a   Easterbrook, Philippa ^a   Wiktor, Stefan ^a  

^a WORLD HEALTH ORGANIZATION   (Switzerland)

^b Treatment Action Group   (United States)

Author keywords

Access; Direct acting antivirals; Scale up.; Simplification

Indexed keywords

ANTIVIRUS AGENT; DIRECT ACTING ANTIVIRAL; UNCLASSIFIED DRUG;

ANTIVIRAL THERAPY; ARTICLE; DECENTRALIZATION; DRUG BIOAVAILABILITY; DRUG COST; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; GENOTYPE; HEALTH CARE ACCESS; HEALTH CARE DELIVERY; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; LIVER DISEASE; NONHUMAN; PREVALENCE; SCREENING TEST; SELF CARE; TREATMENT DURATION; VIREMIA; DEVELOPING COUNTRY; DRUG EFFECTS; ECONOMICS; GENETICS; HEALTH CARE COST; HEALTH CARE PLANNING; HEPACIVIRUS; PUBLIC HEALTH; STANDARDS; SUPPLY AND DISTRIBUTION; TREATMENT OUTCOME; TRENDS; WORLD HEALTH ORGANIZATION;

ANTIVIRAL AGENTS; DELIVERY OF HEALTH CARE; DEVELOPING COUNTRIES; GENOTYPE; HEALTH CARE COSTS; HEALTH RESOURCES; HEALTH SERVICES ACCESSIBILITY; HEPACIVIRUS; HEPATITIS C; HUMANS; PUBLIC HEALTH; TREATMENT OUTCOME; WORLD HEALTH ORGANIZATION;

EID: 84913599128     PISSN: 01688278     EISSN: 16000641     Source Type: Journal    
DOI: 10.1016/j.jhep.2014.09.019     Document Type: Review

References (36)

1. Anon Guidelines for the screening, care and treatment of persons with hepatitis infection 2014 WHO Geneva
2. G.J. Dore, J. Ward, and M. Thursz Hepatitis C disease burden and strategies to manage the burden (Guest Editors Mark Thursz, Gregory Dore and John Ward) J Viral Hepat 21 2014 1 4
3. K. Mohd Hanafiah, J. Groeger, A.D. Flaxman, and S.T. Wiersma Global epidemiology of hepatitis C virus infection: new estimates of age-specific antibody to HCV seroprevalence Hepatology 57 2013 1333 1342
4. M.W. Fried, M. Buti, G.J. Dore, R. Flisiak, P. Ferenci, and I. Jacobson Once-daily simeprevir (TMC435) with pegylated interferon and ribavirin in treatment-naive genotype 1 hepatitis C: the randomized PILLAR study Hepatology 58 2013 1918 1929
5. N. Ford, C. Kirby, K. Singh, E.J. Mills, G. Cooke, and A. Kamarulzaman Chronic hepatitis C treatment outcomes in low- and middle-income countries: a systematic review and meta-analysis Bull World Health Organ 90 2012 540 550
6. Sulkowski M, Rodriguez-Torres M, Lalezari JP, Fessel WJ, Mounzer K, Shuhart MC et al. All-oral therapy with sofosbuvir plus ribavirin for the treatment of HCV genotype 1, 2, and 3 infection in patients co-infected with HIV (PHOTON-1) [Abstract]. In: 64th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD 2013) Washington, DC, USA: 1-5 November 2013.
7. E. Lawitz, A. Mangia, D. Wyles, M. Rodriguez-Torres, T. Hassanein, and S.C. Gordon Sofosbuvir for previously untreated chronic hepatitis C infection N Engl J Med 368 2013 1878 1887
8. N. Ford, K. Singh, G.S. Cooke, E.J. Mills, T. von Schoen-Angerer, and A. Kamarulzaman Expanding access to treatment for hepatitis C in resource-limited settings: lessons from HIV/AIDS Clin Infect Dis 54 2012 1465 1472
9. M. Vitoria, S. Vella, and N. Ford Scaling up antiretroviral therapy in resource-limited settings: adapting guidance to meet the challenges Curr Opin HIV AIDS 8 2013 12 18
10. C.F. Gilks, S. Crowley, R. Ekpini, S. Gove, J. Perriens, and Y. Souteyrand The WHO public-health approach to antiretroviral treatment against HIV in resource-limited settings Lancet 368 2006 505 510
11. N. Ford, E. Mills, and A. Calmy Rationing antiretroviral therapy in Africa - Treating too few, too late N Engl J Med 360 2009 1808 1810
12. European Association for Study of Liver EASL Clinical Practice Guidelines: management of hepatitis C virus infection J Hepatol 60 2014 392 420
13. C.P. Brandao, B.L. Marques, V.A. Marques, C.A. Villela-Nogueira, O.K. Do, and M.T. de Paula Simultaneous detection of hepatitis C virus antigen and antibodies in dried blood spots J Clin Virol 57 2013 98 102
14. R. Ramjan, A. Calmy, M. Vitoria, E.J. Mills, A. Hill, and G. Cooke Systematic review and meta-analysis: patient and programme impact of fixed-dose combination antiretroviral therapy Trop Med Int Health 19 2014 501 513
15. P. Clayden, M. Harrington, and T. Swan Hepatitis C drug development catapults on 2013 pipeline report 2014 Treatment Action Group New York
16. M.J. Alter Epidemiology of viral hepatitis and HIV co-infection J Hepatol 44 2006 S6 S9
17. Anon Consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection. Recommendations for a public health approach 2013 WHO Geneva
18. EASL Recommendations on Treatment of Hepatitis C. J Hepatol 2014;61:373-395.
19. Anon World Health Statistics 2014 WHO
20. F.M. Kiweewa, D. Wabwire, J. Nakibuuka, M. Mubiru, D. Bagenda, and P. Musoke Noninferiority of a task-shifting HIV care and treatment model using peer counselors and nurses among Ugandan women initiated on ART: evidence from a randomized trial J Acquir Immune Defic Syndr 63 2013 e125 e132
21. L. Fairall, M.O. Bachmann, C. Lombard, V. Timmerman, K. Uebel, and M. Zwarenstein Task shifting of antiretroviral treatment from doctors to primary-care nurses in South Africa (STRETCH): a pragmatic, parallel, cluster-randomised trial Lancet 380 2012 889 898
22. I. Sanne, C. Orrell, M.P. Fox, F. Conradie, P. Ive, and J. Zeinecker Nurse versus doctor management of HIV-infected patients receiving antiretroviral therapy (CIPRA-SA): a randomised non-inferiority trial Lancet 376 2010 33 40
23. H.M. Selke, S. Kimaiyo, J.E. Sidle, R. Vedanthan, W.M. Tierney, and C. Shen Task-shifting of antiretroviral delivery from health care workers to persons living with HIV/AIDS: clinical outcomes of a community-based program in Kenya J Acquir Immune Defic Syndr 55 2010 483 490
24. T. Kredo, N. Ford, F.B. Adeniyi, and P. Garner Decentralising HIV treatment in lower- and middle-income countries Cochrane Database Syst Rev 6 2013 CD009987
25. S. Arora, K. Thornton, G. Murata, P. Deming, S. Kalishman, and D. Dion Outcomes of treatment for hepatitis C virus infection by primary care providers N Engl J Med 364 2011 2199 2207
26. W.D. Hill, G. Butt, M. Alvarez, and M. Krajden Capacity enhancement of hepatitis C virus treatment through integrated, community-based care Can J Gastroenterol 22 2008 27 32
27. A.R. Lloyd, J. Clegg, J. Lange, A. Stevenson, J.J. Post, and D. Lloyd Safety and effectiveness of a nurse-led outreach program for assessment and treatment of chronic hepatitis C in the custodial setting Clin Infect Dis 56 2013 1078 1084
28. A.B. Suthar, G.W. Rutherford, T. Horvath, M.C. Doherty, and E.K. Negussie Improving antiretroviral therapy scale-up and effectiveness through service integration and decentralization AIDS 28 2014 S175 S185
29. D. Swendeman, and M.J. Rotheram-Borus Common elements in self-management of HIV and other chronic illnesses: an integrative framework AIDS Care 21 2009 1321 1334
30. E.J. Mills, J.B. Nachega, I. Buchan, J. Orbinski, A. Attaran, and S. Singh Adherence to antiretroviral therapy in sub-Saharan Africa and North America: a meta-analysis JAMA 296 2006 679 690
31. N. Ford, J.B. Nachega, M.E. Engel, and E.J. Mills Directly observed antiretroviral therapy: a systematic review and meta-analysis of randomised clinical trials Lancet 374 2009 2064 2071
32. N.C. Ware, J. Idoko, S. Kaaya, I.A. Biraro, M.A. Wyatt, and O. Agbaji Explaining adherence success in sub-Saharan Africa: an ethnographic study PLoS Med 6 2009 e11
33. A. Hill, S. Khoo, J. Fortunak, B. Simmons, and N. Ford Minimum costs for producing hepatitis C direct-acting antivirals for use in large-scale treatment access programs in developing countries Clin Infect Dis 58 2014 928 936
34. B. Schwartlander, I. Grubb, and J. Perriens The 10-year struggle to provide antiretroviral treatment to people with HIV in the developing world Lancet 368 2006 541 546
35. World Health Assembly Resolution EB126.R16. Viral hepatitis, Geneva, 2010.
36. World Health Assembly Resolution EB134.R18. Hepatitis, Geneva, 2014.