Systemic gene dysregulation in classical Galactosaemia: Is there a central mechanism?

Molecular Genetics and Metabolism

Volumn 113, Issue 3, 2014, Pages 177-187

  Coss, K P ^a   Treacy, E P ^a,b,c   Cotter, E J ^a   Knerr, I ^b   Murray, D W ^d   Shin, Y S ^e   Doran, P P ^a  

^a MATER MISERICORDIAE UNIVERSITY HOSPITAL   (Ireland)

^b National Centre for Inherited Metabolic Disorders   (Ireland)

^c TRINITY COLLEGE DUBLIN   (Ireland)

^d ROYAL COLLEGE OF SURGEONS IN IRELAND   (Ireland)

^e LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

Author keywords

Biomarkers; Galactosaemia; Genomics; Glycosylation; Inflammation

Indexed keywords

GALACTOSE; GALACTOSE 1 PHOSPHATE URIDYLYLTRANSFERASE; GLYCAN; GLYCOSPHINGOLIPID; GLYCOSYLPHOSPHATIDYLINOSITOL; LIPOCORTIN 1; MANNOSYLTRANSFERASE; PHOSPHATIDYLINOSITOL; ALG9 PROTEIN, HUMAN; MEMBRANE PROTEIN; TRANSCRIPTOME;

ADOLESCENT; ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DIET RESTRICTION; DNA MICROARRAY; DOWN REGULATION; FEMALE; GALACTOSEMIA; GENE CONTROL; GENE EXPRESSION; GLYCOSYLATION; HUMAN; HUMAN CELL; LIPOGENESIS; MALE; MICROARRAY ANALYSIS; OXIDATIVE PHOSPHORYLATION; PATHOPHYSIOLOGY; PROTEIN DEGRADATION; SIGNAL TRANSDUCTION; SKIN FIBROBLAST; T LYMPHOCYTE; UNFOLDED PROTEIN RESPONSE; UPREGULATION; YOUNG ADULT; CASE CONTROL STUDY; CELL LINE; GENE REGULATORY NETWORK; GENETICS; METABOLISM;

ADOLESCENT; ADULT; ANNEXIN A1; CASE-CONTROL STUDIES; CELL LINE; FEMALE; GALACTOSEMIAS; GENE REGULATORY NETWORKS; HUMANS; MALE; MANNOSYLTRANSFERASES; MEMBRANE PROTEINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; T-LYMPHOCYTES; TRANSCRIPTOME; YOUNG ADULT;

EID: 84913595989     PISSN: 10967192     EISSN: 10967206     Source Type: Journal    
DOI: 10.1016/j.ymgme.2014.08.004     Document Type: Article

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