Development of a continuous plug flow process for preparation of a key intermediate for brivanib alaninate

Organic Process Research and Development

Volumn 18, Issue 11, 2014, Pages 1492-1502

  Laporte, Thomas L ^a   Spangler, Lori ^a   Hamedi, Mourad ^a   Lobben, Paul ^a   Chan, Steven H ^a   Muslehiddinoglu, Jale ^a   Wang, Steve S Y ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PILOT PLANTS;

BRIVANIB ALANINATE; CONTINUOUS PROCESS; HAZARD ANALYSIS; IN-LINE STATIC MIXERS; PROCESS DEVELOPMENT; REACTION ENGINEERING; TERTIARY ALCOHOLS; THERMAL RUNAWAYS;

SYNTHESIS (CHEMICAL);

EID: 84913582923     PISSN: 10836160     EISSN: 1520586X     Source Type: Journal    
DOI: 10.1021/op500176z     Document Type: Article

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