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Volumn 6, Issue 6, 2002, Pages 884-892

Development of a continuous process for the industrial generation of diazomethane

Author keywords

[No Author keywords available]

Indexed keywords

BUTANOL; CYSTEINE DERIVATIVE; DIAZOMETHANE; PROTEINASE INHIBITOR;

EID: 0036857594     PISSN: 10836160     EISSN: None     Source Type: Journal    
DOI: 10.1021/op020049k     Document Type: Conference Paper
Times cited : (154)

References (38)
  • 1
    • 0011835203 scopus 로고    scopus 로고
    • note
    • (a) This is a transcript of part of a lecture entitled "Continuous Processing Technology Applications in the Fine Chemical Industry" given at the Third International Conference on Organic Process Research and Development, Montreal, July 10-12, 2000.
  • 3
    • 0002813232 scopus 로고
    • Wiley: New York
    • For a review of diazomethane, see: Pizey, J. S. Synthetic Reagents; Wiley: New York, 1974; Vol. 2, p 65.
    • (1974) Synthetic Reagents , vol.2 , pp. 65
    • Pizey, J.S.1
  • 10
    • 0011870931 scopus 로고    scopus 로고
    • First International Conference on Organic Process Research and Development, San Francisco, November 5-7
    • (a) Agouron Pharmaceuticals. Chemical Development of an HIV Protease Inhibitor. First International Conference on Organic Process Research and Development, San Francisco, November 5-7, 1997.
    • (1997) Chemical Development of an HIV Protease Inhibitor
  • 18
    • 0000452649 scopus 로고
    • Wiley: New York
    • Arndt, F. Organic Syntheses; Wiley: New York, 1943; Collect. Vol. II, p 461.
    • (1943) Organic Syntheses , vol.2 , pp. 461
    • Arndt, F.1
  • 22
    • 0011900622 scopus 로고    scopus 로고
    • note
    • (b) All the Diazald studies were carded out in collaboration with Chilworth Technology, Southampton, UK.
  • 23
    • 0011909115 scopus 로고    scopus 로고
    • note
    • UN Transportation of Dangerous Goods Regulations, Test Series C, Test C.2 (TNO Deflagration test).
  • 24
    • 0011874610 scopus 로고    scopus 로고
    • note
    • UN Transportation of Dangerous Goods Regulations, Test Series E, Test E.2 (DPV test).
  • 25
    • 0011867876 scopus 로고    scopus 로고
    • note
    • UN Transportation of Dangerous Goods Regulations, Test Series H, Test H.4.
  • 26
    • 0011874433 scopus 로고    scopus 로고
    • note
    • Diazald should be classified for packaging and transportation as follows: N-methyl-N-nitroso-p-toluene sulphonamide wetted with not less than 15% water (DIAZALD (85%w/w with water)). Self-Reactive Solid, Type D, Temperature-Controlled, UN Number 3236, UN Class 4.1, temperature control conditions: SADT = 40 °C, control temperature = 30 °C, emergency temperature = 35 °C, packing group II (packing instruction 520), packing method OP7 (limits package size to 50 kg net mass).
  • 27
    • 0011874434 scopus 로고    scopus 로고
    • note
    • Testing carried out by Imperial Dynamite Co. Ltd., Neston, UK.
  • 32
    • 0011836541 scopus 로고    scopus 로고
    • First International Conference on Organic Process Research and Development, San Francisco, November 5-7
    • Archibald, T. A. Diazomethane: Commercialization of a Highly Hazardous Material; First International Conference on Organic Process Research and Development, San Francisco, November 5-7, 1997.
    • (1997) Diazomethane: Commercialization of a Highly Hazardous Material
    • Archibald, T.A.1
  • 34
    • 0011835416 scopus 로고    scopus 로고
    • note
    • Diazomethane explosion studies were carried out in collaboration with the Centre for Explosion Studies, Aberystwyth, UK.
  • 35
    • 0011911937 scopus 로고    scopus 로고
    • note
    • The details of the subsequent diazomethane chemistry will be covered in a separate publication.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.