Familial hypercholesterolemia in Brazil: Cascade screening program, clinical and genetic aspects

Atherosclerosis

Volumn 238, Issue 1, 2015, Pages 101-107

  Jannes, Cinthia E ^a   Santos, Raul D ^a   de Souza Silva, Pãmela R ^a   Turolla, Luciana ^a   Gagliardi, Ana C M ^a   Marsiglia, Julia D C ^a   Chacra, Ana P ^a   Miname, Marcio H ^a   Rocha, Viviane Z ^a   Filho, Wilson Salgado ^a   Krieger, Jose E ^a   Pereira, Alexandre C ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Apolipoprotein B; Cascade screening; Familial hypercholesterolemia; Index patient; Low density lipoprotein receptor; Mutations

Indexed keywords

APOLIPOPROTEIN B; CHOLESTEROL; GENOMIC DNA; KEXIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN RECEPTOR; SUBTILISIN; PCSK9 PROTEIN, HUMAN; SERINE PROTEINASE;

ADULT; ARTICLE; BRAZIL; CASCADE SCREENING; CHOLESTEROL BLOOD LEVEL; DUTCH LIPID CLINIC NETWORK SCORE; EXON; FAMILIAL HYPERCHOLESTEROLEMIA; FEMALE; FIRST DEGREE RELATIVE; GENE AMPLIFICATION; GENE MUTATION; HETEROZYGOTE; HOMOZYGOTE; HUMAN; LEBANESE; MAJOR CLINICAL STUDY; MALE; MULTIPLEX LIGATION DEPENDENT PROBE AMPLIFICATION; NAMED INVENTORIES, QUESTIONNAIRES AND RATING SCALES; PREDICTIVE VALUE; PROMOTER REGION; PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9 GENE; SCREENING TEST; SENSITIVITY AND SPECIFICITY; SIMON BROOME SCORE; AGED; BLOOD; BODY MASS; GENETIC PREDISPOSITION; GENETIC SCREENING; GENETICS; HYPERLIPOPROTEINEMIA TYPE II; LEBANON; MASS SCREENING; MIDDLE AGED; MUTATION;

ADULT; AGED; APOLIPOPROTEINS B; BODY MASS INDEX; BRAZIL; EXONS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENETIC TESTING; HETEROZYGOTE; HUMANS; HYPERLIPOPROTEINEMIA TYPE II; LEBANON; MALE; MASS SCREENING; MIDDLE AGED; MUTATION; PREDICTIVE VALUE OF TESTS; PROPROTEIN CONVERTASES; SERINE ENDOPEPTIDASES;

EID: 84913582633     PISSN: 00219150     EISSN: 18791484     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2014.11.009     Document Type: Article

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