Founder mutations in the Netherlands: Geographical distribution of the most prevalent mutations in the low-density lipoprotein receptor and apolipoprotein b genes

Netherlands Heart Journal

Volumn 19, Issue 4, 2011, Pages 175-182

  Kusters, D M ^a   Huijgen, R ^a   Defesche, J C ^a   Vissers, M N ^a   Kindt, I ^b   Hutten, B A ^a   Kastelein, J J P ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b Foundation for the Identification of Persons with Inherited Hypercholesterolemia   (Netherlands)

Author keywords

ApoB gene; Familial hypercholesterolemia; Founder effect; Genetic screening; Homozygosity; LDL cholesterol; LDL receptor gene

Indexed keywords

APOLIPOPROTEIN B; LOW DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN RECEPTOR;

ARTICLE; CLINICAL EFFECTIVENESS; CONTROLLED STUDY; FAMILIAL HYPERCHOLESTEROLEMIA; FOUNDER EFFECT; GENE MUTATION; GENETIC SCREENING; GEOGRAPHIC DISTRIBUTION; HEALTH PROGRAM; HETEROZYGOTE; HOMOZYGOTE; HUMAN; LIPID ANALYSIS; MAJOR CLINICAL STUDY; MUTATIONAL ANALYSIS; NETHERLANDS; PATIENT IDENTIFICATION; PHENOTYPE; POPULATION DISTRIBUTION; PREVALENCE;

EID: 79955402735     PISSN: 15685888     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12471-011-0076-6     Document Type: Article

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