The microRNA-15 family inhibits the TGFβ-pathway in the heart

Cardiovascular Research

Volumn 104, Issue 1, 2014, Pages 61-71

  Tijsen, Anke J ^a   Van Der Made, Ingeborg ^a   Van Den Hoogenhof, Maarten M ^a   Wijnen, Wino J ^a   Van Deel, Elza D ^b   De Groot, Nina E ^a   Alekseev, Sergey ^a   Fluiter, Kees ^a   Schroen, Blanche ^c   Goumans, Marie Jose ^d   Van Der Velden, Jolanda ^e   Duncker, Dirk J ^b   Pinto, Yigal M ^a   Creemers, Esther E ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b ERASMUS MEDICAL CENTER   (Netherlands)

^c MAASTRICHT UNIVERSITY   (Netherlands)

^d LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^e VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Fibrosis; Hypertrophy; miRNA 15 family; TGF pathway

Indexed keywords

ENDOGLIN; MICRORNA; MICRORNA 15B; MITOGEN ACTIVATED PROTEIN KINASE P38; SMAD3 PROTEIN; SMAD7 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; 3' UNTRANSLATED REGION; MIRN15 MICRORNA, HUMAN; MIRN15 MICRORNA, MOUSE; MIRN15 MICRORNA, RAT; PROTEIN SERINE THREONINE KINASE; TGF-BETA TYPE I RECEPTOR; TRANSFORMING GROWTH FACTOR BETA RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; AORTA CONSTRICTION; ARTICLE; CONTROLLED STUDY; HEART; HEART FAILURE; HEART HYPERTROPHY; HEART MUSCLE FIBROSIS; HEART VENTRICLE HYPERTROPHY; HUMAN; HUMAN CELL; NEWBORN; NONHUMAN; PROTEIN FAMILY; RAT; SPECIES; UPREGULATION; 3' UNTRANSLATED REGION; ANIMAL; C57BL MOUSE; CARDIOMEGALY; CARDIOMYOPATHY; CASE CONTROL STUDY; CHLOROCEBUS AETHIOPS; COS 1 CELL LINE; DISEASE MODEL; FIBROSIS; GENETIC TRANSFECTION; GENETICS; HEART MUSCLE CELL; HEART VENTRICLE REMODELING; HEPG2 CELL LINE; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; SIGNAL TRANSDUCTION; TRANSGENIC RAT;

3' UNTRANSLATED REGIONS; ANIMALS; CARDIOMEGALY; CARDIOMYOPATHIES; CASE-CONTROL STUDIES; CERCOPITHECUS AETHIOPS; COS CELLS; DISEASE MODELS, ANIMAL; FIBROSIS; HEP G2 CELLS; HUMANS; MICE, INBRED C57BL; MICRORNAS; MYOCYTES, CARDIAC; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; RATS, TRANSGENIC; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; SIGNAL TRANSDUCTION; SMAD3 PROTEIN; SMAD7 PROTEIN; TRANSFECTION; TRANSFORMING GROWTH FACTOR BETA; UP-REGULATION; VENTRICULAR REMODELING;

EID: 84913580883     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvu184     Document Type: Article

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