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Bioorganic and Medicinal Chemistry Letters

Volumn 25, Issue 1, 2015, Pages 88-91

Novel azoles as potent and selective cannabinoid CB2 receptor agonists

(9) Harnett, Jeremiah J a Dolo, Christine a Viossat, Isabelle a Auger, Florence a Ferrandis, Eric a Bigg, Dennis a Auguet, Michel a Auvin, Serge a Chabrier, Pierre E a

a IPSEN (France)

Author keywords

Antioxidants; Cannabinoid agonists; Chimeric molecules; Dual acting molecules; Human CB2 agonists; Synthesis

Indexed keywords

3 (2 IODO 5 NITROBENZOYL) 1 (1 METHYL 2 PIPERIDINYLMETHYL)INDOLE; CANNABINOID 1 RECEPTOR; CANNABINOID 2 RECEPTOR; CANNABINOID 2 RECEPTOR AGONIST; FORSKOLIN; PYRROLE DERIVATIVE; CANNABINOID; CANNABINOID RECEPTOR AGONIST;

AEROBIC METABOLISM; AMINATION; ANTIOXIDANT ACTIVITY; ARTICLE; BINDING AFFINITY; BIOASSAY; DRUG POTENCY; DRUG SCREENING; DRUG SELECTIVITY; IC50; LIPID PEROXIDATION; NUCLEOPHILICITY; PHARMACOPHORE; RECEPTOR AFFINITY; SUBSTITUTION REACTION; AGONISTS; ANIMAL; CHEMISTRY; CHO CELL LINE; CRICETULUS; HAMSTER; HUMAN; METABOLISM;

ANIMALS; AZOLES; CANNABINOID RECEPTOR AGONISTS; CANNABINOIDS; CHO CELLS; CRICETINAE; CRICETULUS; HUMANS; RECEPTOR, CANNABINOID, CB2;

EID: 84913568923 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2014.11.003 Document Type: Article

Times cited : (4)

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