-
1
-
-
84876149257
-
Global epidemiology of hepatitis C virus infection: New estimates of age-specific antibody to HCV seroprevalence
-
K. Mohd Hanafiah, J. Groeger, A.D. Flaxman, and S.T. Wiersma Global epidemiology of hepatitis C virus infection: new estimates of age-specific antibody to HCV seroprevalence Hepatology 57 2013 1333 1342
-
(2013)
Hepatology
, vol.57
, pp. 1333-1342
-
-
Mohd Hanafiah, K.1
Groeger, J.2
Flaxman, A.D.3
Wiersma, S.T.4
-
3
-
-
0345188811
-
Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line
-
V. Lohmann, F. Körner, J. Koch, U. Herian, L. Theilmann, and R. Bartenschlager Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line Science 285 1999 110 113
-
(1999)
Science
, vol.285
, pp. 110-113
-
-
Lohmann, V.1
Körner, F.2
Koch, J.3
Herian, U.4
Theilmann, L.5
Bartenschlager, R.6
-
4
-
-
84896289180
-
On the history of hepatitis C virus cell culture systems
-
V. Lohmann, and R. Bartenschlager On the history of hepatitis C virus cell culture systems J Med Chem 57 2014 1627 1642
-
(2014)
J Med Chem
, vol.57
, pp. 1627-1642
-
-
Lohmann, V.1
Bartenschlager, R.2
-
5
-
-
84879420038
-
The molecular and structural basis of advanced antiviral therapy for hepatitis C virus infection
-
R. Bartenschlager, V. Lohmann, and F. Penin The molecular and structural basis of advanced antiviral therapy for hepatitis C virus infection Nat Rev Microbiol 11 2013 482 496
-
(2013)
Nat Rev Microbiol
, vol.11
, pp. 482-496
-
-
Bartenschlager, R.1
Lohmann, V.2
Penin, F.3
-
6
-
-
84899628921
-
New hepatitis C therapies
-
J.M. Pawlotsky (Guest Editor) New hepatitis C therapies Semin Liver Dis 34 2014 7 8
-
(2014)
Semin Liver Dis
, vol.34
, pp. 7-8
-
-
Pawlotsky, J.M.1
-
7
-
-
84885772855
-
Host-targeting agents in the treatment of hepatitis C: A beginning and an end?
-
J.M. Baugh, J.A. Garcia-Rivera, and P.A. Gallay Host-targeting agents in the treatment of hepatitis C: a beginning and an end? Antiviral Res 100 2013 555 561
-
(2013)
Antiviral Res
, vol.100
, pp. 555-561
-
-
Baugh, J.M.1
Garcia-Rivera, J.A.2
Gallay, P.A.3
-
8
-
-
84856159009
-
Preliminary study of two antiviral agents for hepatitis C genotype 1
-
A.S. Lok, D.F. Gardiner, E. Lawitz, C. Martorell, G.T. Everson, and R. Ghalib Preliminary study of two antiviral agents for hepatitis C genotype 1 N Engl J Med 366 2012 216 224
-
(2012)
N Engl J Med
, vol.366
, pp. 216-224
-
-
Lok, A.S.1
Gardiner, D.F.2
Lawitz, E.3
Martorell, C.4
Everson, G.T.5
Ghalib, R.6
-
9
-
-
79959438789
-
Telaprevir for previously untreated chronic hepatitis C virus infection
-
I.M. Jacobson, J.G. McHutchison, G. Dusheiko, Adrian M. Di Bisceglie, and K.R. Reddy Telaprevir for previously untreated chronic hepatitis C virus infection N Engl J Med 364 2011 2405 2416
-
(2011)
N Engl J Med
, vol.364
, pp. 2405-2416
-
-
Jacobson, I.M.1
McHutchison, J.G.2
Dusheiko, G.3
Di Bisceglie, A.M.4
Reddy, K.R.5
-
10
-
-
79959381354
-
Telaprevir for retreatment of HCV infection
-
S. Zeuzem, P. Andreone, S. Pol, E. Lawitz, M. Diago, and S. Roberts Telaprevir for retreatment of HCV infection N Engl J Med 364 2011 2417 2428
-
(2011)
N Engl J Med
, vol.364
, pp. 2417-2428
-
-
Zeuzem, S.1
Andreone, P.2
Pol, S.3
Lawitz, E.4
Diago, M.5
Roberts, S.6
-
11
-
-
79953173221
-
Boceprevir for untreated chronic HCV genotype 1 infection
-
F. Poordad, J. McCone, B.R. Bacon, S. Bruno, M.P. Manns, and M.S. Sulkowski Boceprevir for untreated chronic HCV genotype 1 infection N Engl J Med 364 2011 1195 1206
-
(2011)
N Engl J Med
, vol.364
, pp. 1195-1206
-
-
Poordad, F.1
McCone, J.2
Bacon, B.R.3
Bruno, S.4
Manns, M.P.5
Sulkowski, M.S.6
-
12
-
-
84877730954
-
Sofosbuvir for previously untreated chronic hepatitis C infection
-
E. Lawitz, A. Mangia, D. Wyles, M. Rodriguez-Torres, T. Hassanein, and S.C. Gordon Sofosbuvir for previously untreated chronic hepatitis C infection N Engl J Med 368 2013 1878 1887
-
(2013)
N Engl J Med
, vol.368
, pp. 1878-1887
-
-
Lawitz, E.1
Mangia, A.2
Wyles, D.3
Rodriguez-Torres, M.4
Hassanein, T.5
Gordon, S.C.6
-
13
-
-
84877739274
-
Sofosbuvir for hepatitis C genotype 2 or 3 in patients without treatment options
-
I.M. Jacobson, S.C. Gordon, K.V. Kowdley, E.M. Yoshida, M. Rodriguez-Torres, and M.S. Sulkowski Sofosbuvir for hepatitis C genotype 2 or 3 in patients without treatment options N Engl J Med 368 2013 1867 1877
-
(2013)
N Engl J Med
, vol.368
, pp. 1867-1877
-
-
Jacobson, I.M.1
Gordon, S.C.2
Kowdley, K.V.3
Yoshida, E.M.4
Rodriguez-Torres, M.5
Sulkowski, M.S.6
-
14
-
-
84900992889
-
Sofosbuvir and ribavirin in HCV genotypes 2 and 3
-
S. Zeuzem, G.M. Dusheiko, R. Salupere, A. Mangia, R. Flisiak, and R.H. Hyland Sofosbuvir and ribavirin in HCV genotypes 2 and 3 N Engl J Med 370 2014 1993 2001
-
(2014)
N Engl J Med
, vol.370
, pp. 1993-2001
-
-
Zeuzem, S.1
Dusheiko, G.M.2
Salupere, R.3
Mangia, A.4
Flisiak, R.5
Hyland, R.H.6
-
15
-
-
84907447002
-
Once-daily simeprevir (TMC435) plus sofosbuvir (GS-7977) with or without ribavirin in HCV genotype 1 prior null responders with Metavir F0-2: COSMOS Study subgroup analysis
-
M. Sulkowski, I.M. Jacobson, R. Ghalib, M. Rodriguez-Torres, Z. Younossi, and A. Corregidor Once-daily simeprevir (TMC435) plus sofosbuvir (GS-7977) with or without ribavirin in HCV genotype 1 prior null responders with Metavir F0-2: COSMOS Study subgroup analysis J Hepatol 60 2014 S4
-
(2014)
J Hepatol
, vol.60
, pp. 4
-
-
Sulkowski, M.1
Jacobson, I.M.2
Ghalib, R.3
Rodriguez-Torres, M.4
Younossi, Z.5
Corregidor, A.6
-
16
-
-
84902529217
-
Simeprevir plus sofosbuvir with/without ribavirin in HCV genotype 1 prior null-responder/treatment-naïve patients (COSMOS study): Primary endpoint (SVR12) results in patients with Metavir F3-4 (Cohort 2)
-
E. Lawitz, R. Ghalib, M. Rodriguez-Torres, Z.M. Younossi, A. Corregidor, and M.S. Sulkowski Simeprevir plus sofosbuvir with/without ribavirin in HCV genotype 1 prior null-responder/treatment-naïve patients (COSMOS study): primary endpoint (SVR12) results in patients with Metavir F3-4 (Cohort 2) J Hepatol 60 2014 S524
-
(2014)
J Hepatol
, vol.60
, pp. 524
-
-
Lawitz, E.1
Ghalib, R.2
Rodriguez-Torres, M.3
Younossi, Z.M.4
Corregidor, A.5
Sulkowski, M.S.6
-
17
-
-
84892619580
-
Daclatasvir plus sofosbuvir for previously treated or untreated chronic HCV infection
-
M.S. Sulkowski, D.F. Gardiner, M. Rodriguez-Torres, K.R. Reddy, T. Hassanein, and I. Jacobson Daclatasvir plus sofosbuvir for previously treated or untreated chronic HCV infection N Engl J Med 370 2014 211 221
-
(2014)
N Engl J Med
, vol.370
, pp. 211-221
-
-
Sulkowski, M.S.1
Gardiner, D.F.2
Rodriguez-Torres, M.3
Reddy, K.R.4
Hassanein, T.5
Jacobson, I.6
-
18
-
-
84900339263
-
Ledipasvir and sofosbuvir for untreated HCV genotype 1 infection
-
N. Afdhal, S. Zeuzem, P. Kwo, M. Chojkier, N. Gitlin, and M. Puoti Ledipasvir and sofosbuvir for untreated HCV genotype 1 infection N Engl J Med 370 2014 1889 1898
-
(2014)
N Engl J Med
, vol.370
, pp. 1889-1898
-
-
Afdhal, N.1
Zeuzem, S.2
Kwo, P.3
Chojkier, M.4
Gitlin, N.5
Puoti, M.6
-
19
-
-
84898669547
-
Ledipasvir and sofosbuvir for previously treated HCV genotype 1 infection
-
N. Afdhal, K.R. Reddy, D.R. Nelson, E. Lawitz, S.C. Gordon, and E. Schiff Ledipasvir and sofosbuvir for previously treated HCV genotype 1 infection N Engl J Med 370 2014 1483 1493
-
(2014)
N Engl J Med
, vol.370
, pp. 1483-1493
-
-
Afdhal, N.1
Reddy, K.R.2
Nelson, D.R.3
Lawitz, E.4
Gordon, S.C.5
Schiff, E.6
-
20
-
-
84900326091
-
Ledipasvir and sofosbuvir for 8 or 12 weeks for chronic HCV without cirrhosis
-
K.V. Kowdley, S.C. Gordon, K.R. Reddy, L. Rossaro, D.E. Bernstein, and E. Lawitz Ledipasvir and sofosbuvir for 8 or 12 weeks for chronic HCV without cirrhosis N Engl J Med 370 2014 1879 1888
-
(2014)
N Engl J Med
, vol.370
, pp. 1879-1888
-
-
Kowdley, K.V.1
Gordon, S.C.2
Reddy, K.R.3
Rossaro, L.4
Bernstein, D.E.5
Lawitz, E.6
-
21
-
-
84898441875
-
MK-5172: A second-generation protease inhibitor for the treatment of hepatitis C virus infection
-
I. Gentile, A.R. Buonomo, F. Borgia, E. Zappulo, G. Castaldo, and G. Borgia MK-5172: a second-generation protease inhibitor for the treatment of hepatitis C virus infection Expert Opin Investig Drugs 23 2014 719 728
-
(2014)
Expert Opin Investig Drugs
, vol.23
, pp. 719-728
-
-
Gentile, I.1
Buonomo, A.R.2
Borgia, F.3
Zappulo, E.4
Castaldo, G.5
Borgia, G.6
-
22
-
-
84913600667
-
ABT-493, a potent HCV NS3/4A protease inhibitor with broad genotype coverage
-
T. Ng, T. Reisch, T. Middleton, K. McDaniel, D. Kempf, and L. Lu ABT-493, a potent HCV NS3/4A protease inhibitor with broad genotype coverage Top Antivir Med 22 2014 314
-
(2014)
Top Antivir Med
, vol.22
, pp. 314
-
-
Ng, T.1
Reisch, T.2
Middleton, T.3
McDaniel, K.4
Kempf, D.5
Lu, L.6
-
23
-
-
84889888952
-
Discovery of MK-8742: An HCV NS5A inhibitor with broad genotype activity
-
C.A. Coburn, P.T. Meinke, W. Chang, C.M. Fandozzi, D.J. Graham, and B. Hu Discovery of MK-8742: an HCV NS5A inhibitor with broad genotype activity ChemMedChem 8 2013 1930 1940
-
(2013)
ChemMedChem
, vol.8
, pp. 1930-1940
-
-
Coburn, C.A.1
Meinke, P.T.2
Chang, W.3
Fandozzi, C.M.4
Graham, D.J.5
Hu, B.6
-
24
-
-
84896296896
-
1191 GS-5816, a second generation HCV NS5A inhibitor with potent antiviral activity, broad genotypic coverage and a high resistance barrier
-
G. Cheng, M. Yu, B. Peng, Y. Lee, A. Trejo-Martin, and R. Gong 1191 GS-5816, a second generation HCV NS5A inhibitor with potent antiviral activity, broad genotypic coverage and a high resistance barrier J Hepatol 58 2013 S484
-
(2013)
J Hepatol
, vol.58
, pp. 484
-
-
Cheng, G.1
Yu, M.2
Peng, B.3
Lee, Y.4
Trejo-Martin, A.5
Gong, R.6
-
25
-
-
84891533036
-
Preclinical characterization of GSK2336805, a novel inhibitor of hepatitis C virus replication that selects for resistance in NS5A
-
J. Walker, R. Crosby, A. Wang, E. Woldu, J. Vamathevan, and C. Voitenleitner Preclinical characterization of GSK2336805, a novel inhibitor of hepatitis C virus replication that selects for resistance in NS5A Antimicrob Agents Chemother 58 2014 38 47
-
(2014)
Antimicrob Agents Chemother
, vol.58
, pp. 38-47
-
-
Walker, J.1
Crosby, R.2
Wang, A.3
Woldu, E.4
Vamathevan, J.5
Voitenleitner, C.6
-
26
-
-
84913601199
-
ABT-530, an HCV NS5A inhibitor with potent pangenotypic activity and high barrier to resistance
-
T. Ng, P. Krishnan, W. Kati, T. Reisch, L. Lu, and T. Dekhtyar ABT-530, an HCV NS5A inhibitor with potent pangenotypic activity and high barrier to resistance Top Antivir Med 22 2014 315
-
(2014)
Top Antivir Med
, vol.22
, pp. 315
-
-
Ng, T.1
Krishnan, P.2
Kati, W.3
Reisch, T.4
Lu, L.5
Dekhtyar, T.6
-
27
-
-
84892591928
-
Phase 2b trial of interferon-free therapy for hepatitis C virus genotype 1
-
K.V. Kowdley, E. Lawitz, F. Poordad, D.E. Cohen, D.R. Nelson, and S. Zeuzem Phase 2b trial of interferon-free therapy for hepatitis C virus genotype 1 N Engl J Med 370 2014 222 232
-
(2014)
N Engl J Med
, vol.370
, pp. 222-232
-
-
Kowdley, K.V.1
Lawitz, E.2
Poordad, F.3
Cohen, D.E.4
Nelson, D.R.5
Zeuzem, S.6
-
28
-
-
84896698870
-
Interferon- and ribavirin-free regimen of ABT-450/r + ABT-267 in HCV genotype 1b-infected treatment-naïve patients and prior null responders
-
E. Lawitz, C. Hezode, P. Varunok, P.J. Thuluvath, T. Baykal, and M. Kapoor Interferon- and ribavirin-free regimen of ABT-450/r + ABT-267 in HCV genotype 1b-infected treatment-naïve patients and prior null responders Hepatology 58 2013 62A
-
(2013)
Hepatology
, vol.58
, pp. 62A
-
-
Lawitz, E.1
Hezode, C.2
Varunok, P.3
Thuluvath, P.J.4
Baykal, T.5
Kapoor, M.6
-
29
-
-
84908100925
-
Results from the phase 2 PEARL-I study: Interferon-free regimens of ABT-450/R + ABT-267 with or without ribavirin in patients with HCV genotype 4 infection
-
C. Hezode, P. Marcellin, S. Pol, T. Hassanein, K. Fleischer-Stepniewska, and T. Baykal Results from the phase 2 PEARL-I study: interferon-free regimens of ABT-450/R + ABT-267 with or without ribavirin in patients with HCV genotype 4 infection J Hepatol 60 2014 S24
-
(2014)
J Hepatol
, vol.60
, pp. 24
-
-
Hezode, C.1
Marcellin, P.2
Pol, S.3
Hassanein, T.4
Fleischer-Stepniewska, K.5
Baykal, T.6
-
30
-
-
84913545145
-
-
[accessed on 30.08.14]
-
< http://www.clinicaltrials.gov/ct2/show/NCT02068222 > [accessed on 30.08.14].
-
-
-
-
31
-
-
84913533797
-
SVR4 results for the combination of ACH-3102 and sovaprevir, with ribavirin, in subjects with genotype 1 chronic hepatitis C infection
-
A. Muir, F. Poordad, A. Sheikh, M. Elkashab, and R. Brennan SVR4 results for the combination of ACH-3102 and sovaprevir, with ribavirin, in subjects with genotype 1 chronic hepatitis C infection Hepatol Int 8 2014 395
-
(2014)
Hepatol Int
, vol.8
, pp. 395
-
-
Muir, A.1
Poordad, F.2
Sheikh, A.3
Elkashab, M.4
Brennan, R.5
-
32
-
-
84913545144
-
-
[accessed on 03.08.14]
-
< http://ir.achillion.com/releasedetail.cfm?releaseid=853707 > [accessed on 03.08.14].
-
-
-
-
33
-
-
84879693219
-
Dual oral therapy with daclatasvir and asunaprevir for patients with HCV genotype 1b infection and limited treatment options
-
Y. Suzuki, K. Ikeda, F. Suzuki, J. Toyota, Y. Karino, and K. Chayama Dual oral therapy with daclatasvir and asunaprevir for patients with HCV genotype 1b infection and limited treatment options J Hepatol 58 2013 655 662
-
(2013)
J Hepatol
, vol.58
, pp. 655-662
-
-
Suzuki, Y.1
Ikeda, K.2
Suzuki, F.3
Toyota, J.4
Karino, Y.5
Chayama, K.6
-
34
-
-
84894099866
-
Randomized trial of daclatasvir and asunaprevir with or without PegIFN/RBV for hepatitis C virus genotype 1 null responders
-
A.S. Lok, D.F. Gardiner, C. Hézode, E.J. Lawitz, M. Bourlière, and G.T. Everson Randomized trial of daclatasvir and asunaprevir with or without PegIFN/RBV for hepatitis C virus genotype 1 null responders J Hepatol 60 2014 490 499
-
(2014)
J Hepatol
, vol.60
, pp. 490-499
-
-
Lok, A.S.1
Gardiner, D.F.2
Hézode, C.3
Lawitz, E.J.4
Bourlière, M.5
Everson, G.T.6
-
35
-
-
84901595218
-
Daclatasvir plus asunaprevir for chronic HCV genotype 1b infection
-
H. Kumada, Y. Suzuki, K. Ikeda, J. Toyota, Y. Karino, and K. Chayama Daclatasvir plus asunaprevir for chronic HCV genotype 1b infection Hepatology 59 2014 2083 2091
-
(2014)
Hepatology
, vol.59
, pp. 2083-2091
-
-
Kumada, H.1
Suzuki, Y.2
Ikeda, K.3
Toyota, J.4
Karino, Y.5
Chayama, K.6
-
36
-
-
84900986946
-
All-oral dual therapy with daclatasvir and asunaprevir in patients with HCV genotype 1b infection: Phase 3 study results
-
M. Manns, S. Pol, I. Jacobson, P. Marcellin, S. Gordon, and C. Peng All-oral dual therapy with daclatasvir and asunaprevir in patients with HCV genotype 1b infection: phase 3 study results J Hepatol 60 2014 S524
-
(2014)
J Hepatol
, vol.60
, pp. 524
-
-
Manns, M.1
Pol, S.2
Jacobson, I.3
Marcellin, P.4
Gordon, S.5
Peng, C.6
-
37
-
-
84913532269
-
Daclatasvir in combination with simeprevir ± ribavirin for hepatitis C virus genotype 1 infection (Abstract 28LB)
-
S. Zeuzem, C. Hezode, J.P. Bronowicki, V. Loustad-Ratti, F. Gea, and M. Buti Daclatasvir in combination with simeprevir ± ribavirin for hepatitis C virus genotype 1 infection (Abstract 28LB) Top Antivir Med 22 2014 15 16
-
(2014)
Top Antivir Med
, vol.22
, pp. 15-16
-
-
Zeuzem, S.1
Hezode, C.2
Bronowicki, J.P.3
Loustad-Ratti, V.4
Gea, F.5
Buti, M.6
-
38
-
-
84913595820
-
-
gov: May 19
-
A study of pharmacokinetics, efficacy, safety, tolerability, of the combination of simeprevir (TMC435), daclatasvir (BMS-790052), and ribavirin (RBV) in patients with recurrent chronic hepatitis C genotype 1b infection after orthotopic liver transplantation - Full text view - ClinicalTrials.gov: May 19, 2014; available from: http://www.clinicaltrials.gov/ct2/show/NCT01938625.
-
(2014)
A Study of Pharmacokinetics, Efficacy, Safety, Tolerability, of the Combination of Simeprevir (TMC435), Daclatasvir (BMS-790052), and Ribavirin (RBV) in Patients with Recurrent Chronic Hepatitis C Genotype 1b Infection after Orthotopic Liver Transplantation - Full Text View ClinicalTrials
-
-
-
39
-
-
84913537232
-
A phase II study of samatasvir (IDX719) in combination with simeprevir and ribavirin in treatment naïve HCV-infected subjects with genotypes 1b and 4 (HELIX-1 study)
-
E. Lawitz, M. Rodriguez-Torres, T. Nguyen, A. Sheikh, H. Tobias, and J. Galati A phase II study of samatasvir (IDX719) in combination with simeprevir and ribavirin in treatment naïve HCV-infected subjects with genotypes 1b and 4 (HELIX-1 study) J Hepatol 60 2014 S495
-
(2014)
J Hepatol
, vol.60
, pp. 495
-
-
Lawitz, E.1
Rodriguez-Torres, M.2
Nguyen, T.3
Sheikh, A.4
Tobias, H.5
Galati, J.6
-
40
-
-
84893845406
-
High efficacy and safety of the all-oral combination regimen, MK-5172/MK-8742 +/- RBV for 12 weeks in HCV genotype 1 infected patients: The C- WORTHY Study
-
E. Lawitz, J.M. Vierling, A. Murillo, M. Kugelmas, J. Gerstoft, and P. Winkle High efficacy and safety of the all-oral combination regimen, MK-5172/MK-8742 +/- RBV for 12 weeks in HCV genotype 1 infected patients: the C- WORTHY Study Hepatology 58 2013 62A
-
(2013)
Hepatology
, vol.58
, pp. 62A
-
-
Lawitz, E.1
Vierling, J.M.2
Murillo, A.3
Kugelmas, M.4
Gerstoft, J.5
Winkle, P.6
-
41
-
-
84902496363
-
Safety and efficacy of the all-oral regimen of MK-5172/MK-8742 ± ribavirin in treatment-naïve, non-cirrhotic patients with hepatitis C virus genotype 1 infection: The C-WORTHY study
-
C. Hezode, L. Serfaty, J.M. Vierling, M. Kugelmas, B. Pearlman, and W. Sievert Safety and efficacy of the all-oral regimen of MK-5172/MK-8742 ± ribavirin in treatment-naïve, non-cirrhotic patients with hepatitis C virus genotype 1 infection: The C-WORTHY study J Hepatol 60 2014 S5
-
(2014)
J Hepatol
, vol.60
, pp. 5
-
-
Hezode, C.1
Serfaty, L.2
Vierling, J.M.3
Kugelmas, M.4
Pearlman, B.5
Sievert, W.6
-
42
-
-
84904602144
-
Efficacy and safety of MK-5172 and MK-8742 ± ribavirin in hepatitis C genotype 1 infected patients with cirrhosis or previous null-response: The C-WORTHY study
-
E. Lawitz, C. Hezode, E. Gane, E. Tam, M. Lagging, and L. Balart Efficacy and safety of MK-5172 AND MK-8742 ± ribavirin in hepatitis C genotype 1 infected patients with cirrhosis or previous null-response: The C-WORTHY study J Hepatol 60 2014 S25
-
(2014)
J Hepatol
, vol.60
, pp. 25
-
-
Lawitz, E.1
Hezode, C.2
Gane, E.3
Tam, E.4
Lagging, M.5
Balart, L.6
-
45
-
-
84871765489
-
Exploratory study of oral combination antiviral therapy for hepatitis C
-
F. Poordad, E. Lawitz, K.V. Kowdley, D.E. Cohen, T. Podsadecki, and S. Siggelkow Exploratory study of oral combination antiviral therapy for hepatitis C N Engl J Med 368 2013 45 53
-
(2013)
N Engl J Med
, vol.368
, pp. 45-53
-
-
Poordad, F.1
Lawitz, E.2
Kowdley, K.V.3
Cohen, D.E.4
Podsadecki, T.5
Siggelkow, S.6
-
46
-
-
84879152382
-
A phase 2a trial of 12-week interferon-free therapy with two direct-acting antivirals (ABT-450/r, ABT-072) and ribavirin in IL28B C/C patients with chronic hepatitis C genotype 1
-
E. Lawitz, F. Poordad, K.V. Kowdley, D.E. Cohen, T. Podsadecki, and S. Siggelkow A phase 2a trial of 12-week interferon-free therapy with two direct-acting antivirals (ABT-450/r, ABT-072) and ribavirin in IL28B C/C patients with chronic hepatitis C genotype 1 J Hepatol 59 2013 18 23
-
(2013)
J Hepatol
, vol.59
, pp. 18-23
-
-
Lawitz, E.1
Poordad, F.2
Kowdley, K.V.3
Cohen, D.E.4
Podsadecki, T.5
Siggelkow, S.6
-
47
-
-
84913539309
-
Lack of impact of baseline resistance associated variants (RAVS) on treatment outcome in the aviator study with ABT-450/r, ABT-333, and ABT-267 +/- RBV
-
P. Krishnan, R. Tripathi, M. Irvin, J. Beyer, T. Reisch, and G. Schnell Lack of impact of baseline resistance associated variants (RAVS) on treatment outcome in the aviator study with ABT-450/r, ABT-333, and ABT-267 +/- RBV J Hepatol 60 2014 S498
-
(2014)
J Hepatol
, vol.60
, pp. 498
-
-
Krishnan, P.1
Tripathi, R.2
Irvin, M.3
Beyer, J.4
Reisch, T.5
Schnell, G.6
-
48
-
-
84899068302
-
Treatment of HCV with ABT-450/r-ombitasvir and dasabuvir with ribavirin
-
J.J. Feld, K.V. Kowdley, E. Coakley, S. Sigal, D.R. Nelson, and D. Crawford Treatment of HCV with ABT-450/r-ombitasvir and dasabuvir with ribavirin N Engl J Med 370 2014 1594 1603
-
(2014)
N Engl J Med
, vol.370
, pp. 1594-1603
-
-
Feld, J.J.1
Kowdley, K.V.2
Coakley, E.3
Sigal, S.4
Nelson, D.R.5
Crawford, D.6
-
49
-
-
84899106124
-
Retreatment of HCV with ABT-450/r-ombitasvir and dasabuvir with ribavirin
-
S. Zeuzem, I.M. Jacobson, T. Baykal, R.T. Marinho, F. Poordad, and M. Bourlière Retreatment of HCV with ABT-450/r-ombitasvir and dasabuvir with ribavirin N Engl J Med 370 2014 1604 1614
-
(2014)
N Engl J Med
, vol.370
, pp. 1604-1614
-
-
Zeuzem, S.1
Jacobson, I.M.2
Baykal, T.3
Marinho, R.T.4
Poordad, F.5
Bourlière, M.6
-
50
-
-
84901036125
-
ABT-450/r-ombitasvir and dasabuvir with ribavirin for hepatitis C with cirrhosis
-
F. Poordad, C. Hezode, R. Trinh, K.V. Kowdley, S. Zeuzem, and K. Agarwal ABT-450/r-ombitasvir and dasabuvir with ribavirin for hepatitis C with cirrhosis N Engl J Med 370 2014 1973 1982
-
(2014)
N Engl J Med
, vol.370
, pp. 1973-1982
-
-
Poordad, F.1
Hezode, C.2
Trinh, R.3
Kowdley, K.V.4
Zeuzem, S.5
Agarwal, K.6
-
51
-
-
84901044326
-
ABT-450/r-ombitasvir and dasabuvir with or without ribavirin for HCV
-
P. Ferenci, D. Bernstein, J. Lalezari, D. Cohen, Y. Luo, and C. Cooper ABT-450/r-ombitasvir and dasabuvir with or without ribavirin for HCV N Engl J Med 370 2014 1983 1992
-
(2014)
N Engl J Med
, vol.370
, pp. 1983-1992
-
-
Ferenci, P.1
Bernstein, D.2
Lalezari, J.3
Cohen, D.4
Luo, Y.5
Cooper, C.6
-
52
-
-
84904647749
-
ABT-450, ritonavir, ombitasvir, and dasabuvir achieves 97% and 100% sustained virologic response with or without ribavirin in treatment-experienced patients with HCV genotype 1b infection
-
P. Andreone, M.G. Colombo, J.V. Enejosa, I. Koksal, P. Ferenci, and A. Maieron ABT-450, ritonavir, ombitasvir, and dasabuvir achieves 97% and 100% sustained virologic response with or without ribavirin in treatment-experienced patients with HCV genotype 1b infection Gastroenterology 147 2014 359 365
-
(2014)
Gastroenterology
, vol.147
, pp. 359-365
-
-
Andreone, P.1
Colombo, M.G.2
Enejosa, J.V.3
Koksal, I.4
Ferenci, P.5
Maieron, A.6
-
53
-
-
84904011036
-
Results of the phase 2 study M12-999: Interferon-free regimen of ABT-450/r/ABT-267 + ABT-333 + ribavirin in liver transplant recipients with recurrent HCV genotype 1 infection
-
P. Kwo, P. Mantry, E. Coakley, H. Te, H. Vargas, and R. Brown Results of the phase 2 study M12-999: interferon-free regimen of ABT-450/r/ABT-267 + ABT-333 + ribavirin in liver transplant recipients with recurrent HCV genotype 1 infection J Hepatol 60 2014 S47
-
(2014)
J Hepatol
, vol.60
, pp. 47
-
-
Kwo, P.1
Mantry, P.2
Coakley, E.3
Te, H.4
Vargas, H.5
Brown, R.6
-
54
-
-
84892761609
-
Efficacy of an interferon- and ribavirin-free regimen of daclatasvir, asunaprevir, and BMS-791325 in treatment-naive patients with HCV genotype 1 infection
-
G.T. Everson, K.D. Sims, M. Rodriguez-Torres, C. Hézode, E. Lawitz, and M. Bourlière Efficacy of an interferon- and ribavirin-free regimen of daclatasvir, asunaprevir, and BMS-791325 in treatment-naive patients with HCV genotype 1 infection Gastroenterology 146 2014 420 429
-
(2014)
Gastroenterology
, vol.146
, pp. 420-429
-
-
Everson, G.T.1
Sims, K.D.2
Rodriguez-Torres, M.3
Hézode, C.4
Lawitz, E.5
Bourlière, M.6
-
55
-
-
84893844708
-
LB-1: Phase 2b study of the interferon-free and ribavirin-free combination of daclatasvir, asunaprevir, and BMS-791325 for 12 weeks in treatment-naïve patients with chronic HCV genotype 1 infection
-
G.T. Everson, K.D. Sims, P.J. Thuluvath, E. Lawitz, T. Hassanein, and M. Rodriguez-Torres LB-1: phase 2b study of the interferon-free and ribavirin-free combination of daclatasvir, asunaprevir, and BMS-791325 for 12 weeks in treatment-naïve patients with chronic HCV genotype 1 infection Hepatology 58 2013 1377A
-
(2013)
Hepatology
, vol.58
, pp. 1377A
-
-
Everson, G.T.1
Sims, K.D.2
Thuluvath, P.J.3
Lawitz, E.4
Hassanein, T.5
Rodriguez-Torres, M.6
-
56
-
-
84908092431
-
All-oral therapy with daclatasvir in combination with asunaprevir and BMS-791325 for treatment-naïve patients with chronic HCV genotype 4 infection
-
T. Hassanein, K. Sims, M. Bennett, N. Gitlin, E. Lawitz, and T. Nguyen All-oral therapy with daclatasvir in combination with asunaprevir and BMS-791325 for treatment-naïve patients with chronic HCV genotype 4 infection J Hepatol 60 2014 S472
-
(2014)
J Hepatol
, vol.60
, pp. 472
-
-
Hassanein, T.1
Sims, K.2
Bennett, M.3
Gitlin, N.4
Lawitz, E.5
Nguyen, T.6
-
61
-
-
33646015668
-
The non-immunosuppressive cyclosporin DEBIO-025 is a potent inhibitor of hepatitis C virus replication in vitro
-
J. Paeshuyse, A. Kaul, E. de Clercq, B. Rosenwirth, J. Dumont, and P. Scalfaro The non-immunosuppressive cyclosporin DEBIO-025 is a potent inhibitor of hepatitis C virus replication in vitro Hepatology 43 2006 761 770
-
(2006)
Hepatology
, vol.43
, pp. 761-770
-
-
Paeshuyse, J.1
Kaul, A.2
De Clercq, E.3
Rosenwirth, B.4
Dumont, J.5
Scalfaro, P.6
-
62
-
-
67650550814
-
The isomerase active site of cyclophilin A is critical for hepatitis C virus replication
-
U. Chatterji, M. Bobardt, S. Selvarajah, F. Yang, H. Tang, and N. Sakamoto The isomerase active site of cyclophilin A is critical for hepatitis C virus replication J Biol Chem 284 2009 16998 17005
-
(2009)
J Biol Chem
, vol.284
, pp. 16998-17005
-
-
Chatterji, U.1
Bobardt, M.2
Selvarajah, S.3
Yang, F.4
Tang, H.5
Sakamoto, N.6
-
63
-
-
62949181285
-
Debio 025, a cyclophilin binding molecule, is highly efficient in clearing hepatitis C virus (HCV) replicon-containing cells when used alone or in combination with specifically targeted antiviral therapy for HCV (STAT-C) inhibitors
-
L. Coelmont, S. Kaptein, J. Paeshuyse, I. Vliegen, J. Dumont, and G. Vuagniaux Debio 025, a cyclophilin binding molecule, is highly efficient in clearing hepatitis C virus (HCV) replicon-containing cells when used alone or in combination with specifically targeted antiviral therapy for HCV (STAT-C) inhibitors Antimicrob Agents Chemother 53 2009 967 976
-
(2009)
Antimicrob Agents Chemother
, vol.53
, pp. 967-976
-
-
Coelmont, L.1
Kaptein, S.2
Paeshuyse, J.3
Vliegen, I.4
Dumont, J.5
Vuagniaux, G.6
-
64
-
-
84884818909
-
Targeting miRNAs to treat hepatitis C virus infections and liver pathology: Inhibiting the virus and altering the host
-
P.A. Thibault, and J.A. Wilson Targeting miRNAs to treat hepatitis C virus infections and liver pathology: inhibiting the virus and altering the host Pharmacol Res 75 2013 48 59
-
(2013)
Pharmacol Res
, vol.75
, pp. 48-59
-
-
Thibault, P.A.1
Wilson, J.A.2
-
65
-
-
84877258007
-
Treatment of HCV infection by targeting microRNA
-
Harry L.A. Janssen, H.W. Reesink, E.J. Lawitz, S. Zeuzem, M. Rodriguez-Torres, and K. Patel Treatment of HCV infection by targeting microRNA N Engl J Med 368 2013 1685 1694
-
(2013)
N Engl J Med
, vol.368
, pp. 1685-1694
-
-
Janssen, H.L.A.1
Reesink, H.W.2
Lawitz, E.J.3
Zeuzem, S.4
Rodriguez-Torres, M.5
Patel, K.6
|