Prevention and management of cesarean wound infection

Obstetrics and Gynecology Clinics of North America

Volumn 41, Issue 4, 2014, Pages 671-689

  Fitzwater, Joseph L ^a   Tita, Alan T N ^a  

^a Division of Maternal Fetal Medicine   (United States)

Author keywords

Cesarean; Management; Surgical site infections; Treatment; Wound

Indexed keywords

AMINOGLYCOSIDE; AMPICILLIN; ANTIBIOTIC AGENT; AZITHROMYCIN; AZTREONAM; CARBAPENEM DERIVATIVE; CEPHALOSPORIN; CLINDAMYCIN; CLINDAMYCIN PLUS AMINOGLYCOSIDE; CORTICOSTEROID; PIPERACILLIN PLUS TAZOBACTAM; UNCLASSIFIED DRUG; VANCOMYCIN;

ADD ON THERAPY; ANTIBIOTIC PROPHYLAXIS; ANTIBIOTIC THERAPY; CESAREAN SECTION; CHORIOAMNIONITIS; COMORBIDITY; DEBRIDEMENT; DIABETES MELLITUS; GYNECOLOGICAL EXAMINATION; HEMATOMA; HUMAN; HYPERTENSION; INFECTION PREVENTION; LABOR; LABOR MANAGEMENT; MICROBIOLOGY; MORBIDITY; MULTIPLE PREGNANCY; NECROTIZING FASCIITIS; NUTRITION; OBESITY; OPERATION DURATION; OPERATIVE BLOOD LOSS; PATHOPHYSIOLOGY; PREMATURE FETUS MEMBRANE RUPTURE; PRENATAL CARE; PREVALENCE; REVIEW; SURGICAL INFECTION; TOBACCO USE; WOUND CLOSURE; WOUND DRESSING; WOUND INFECTION; ADULT; ADVERSE EFFECTS; BANDAGE; EARLY DIAGNOSIS; FASCIITIS, NECROTIZING; FEMALE; PRACTICE GUIDELINE; PREGNANCY; PROCEDURES; RISK FACTOR; SURGICAL WOUND INFECTION;

ADULT; ANTIBIOTIC PROPHYLAXIS; BANDAGES; CESAREAN SECTION; DEBRIDEMENT; EARLY DIAGNOSIS; FASCIITIS, NECROTIZING; FEMALE; HUMANS; PRACTICE GUIDELINES AS TOPIC; PREGNANCY; RISK FACTORS; SURGICAL WOUND INFECTION;

EID: 84912533775     PISSN: 08898545     EISSN: 15580474     Source Type: Journal    
DOI: 10.1016/j.ogc.2014.08.008     Document Type: Review

References (72)

1. Horan T.C., Gaynes R.P., Martone W.J., et al. CDC definitions of nosocomial surgical site infections, 1992: a modification of CDC definitions of surgical wound infections. Infect Control Hosp Epidemiol 1992, 13:606-608.
2. Magill S.S., Edwards J.R., Bamberg W., et al. Emerging infections program healthcare-associated infections and antimicrobial use prevalence survey team. Multistate point-prevalence survey of health care-associated infections. NEngl J Med 2014, 370:1198-1208.
3. Cataife G., Weinberg D.A., Wong H.H., et al. The effect of Surgical Care Improvement Project (SCIP) compliance on surgical site infections (SSI). Med Care 2014, 52:S66-S73.
4. Martin J.A., Hamilton B.E., Ventura S.J., et al. Births: final data for 2012. Natl Vital Stat Rep 2013, 62:1-87.
5. Opøien H.K., Valbø A., Grinde-Andersen A., et al. Post-cesarean surgical site infections according to CDC standards: rates and risk factors. A prospective cohort study. Acta Obstet Gynecol Scand 2007, 86:1097-1102.
6. Olsen M.A., Butler A.M., Willers D.M., et al. Risk factors for surgical site infection after low transverse cesarean section. Infect Control Hosp Epidemiol 2008, 29:477-484.
7. Chaim W., Bashiri A., Bar-David J., et al. Prevalence and clinical significance of postpartum endometritis and wound infection. Infect Dis Obstet Gynecol 2000, 8:77-82.
8. Charrier L., Serafini P., Ribatti A., et al. Post-partum surgical wound infections: incidence after caesarean section in an Italian hospital. JPrev Med Hyg 2009, 50:159-163.
9. Schneid-Kofman N., Sheiner E., Levy A., et al. Risk factors for wound infection following cesarean deliveries. Int J Gynaecol Obstet 2005, 90:10-15.
10. Tran T.S., Jamulitrat S., Chongsuvivatwong V., et al. Risk factors for postcesarean surgical site infection. Obstet Gynecol 2000, 95:367-371.
11. Wloch C., Wilson J., Lamagni T., et al. Risk factors for surgical site infection following caesarean section in England: results from a multicentre cohort study. BJOG 2012, 119:1324-1333.
12. Gibbs R.S. Clinical risk factors for puerperal infection. Obstet Gynecol 1980, 55:178S-184S.
13. Sachs B.P., Yeh J., Acker D., et al. Cesarean section-related maternal mortality in Massachusetts, 1954-1985. Obstet Gynecol 1988, 71:385-388.
14. Bodelon C., Bernabe-Ortiz A., Schiff M.A., et al. Factors associated with peripartum hysterectomy. Obstet Gynecol 2009, 114:115-123.
15. de Lissovoy G., Fraeman K., Hutchins V., et al. Surgical site infection: incidence and impact on hospital utilization and treatment costs. Am J Infect Control 2009, 37:387-397.
16. Olsen M.A., Butler A.M., Willers D.M., et al. Comparison of costs of surgical site infection and endometritis after cesarean delivery using claims and medical record data. Infect Control Hosp Epidemiol 2010, 31:872-875.
17. Vermillion S.T., Lamoutte C., Soper D.E., et al. Wound infection after cesarean: effect of subcutaneous tissue thickness. Obstet Gynecol 2000, 95:923-926.
18. Myles T.D., Gooch J., Santolaya J. Obesity as an independent risk factor for infectious morbidity in patients who undergo cesarean delivery. Obstet Gynecol 2002, 100:959-964.
19. Alanis M.C., Villers M.S., Law T.L., et al. Complications of cesarean delivery in the massively obese parturient. Am J Obstet Gynecol 2010, 203:271.e1-271.e7.
20. Avila C., Bhangoo R., Figueroa R., et al. Association of smoking with wound complications after cesarean delivery. JMatern Fetal Neonatal Med 2012, 25:1250-1253.
21. De Vivo A., Mancuso A., Giacobbe A., et al. Wound length and corticosteroid administration as risk factors for surgical-site complications following cesarean section. Acta Obstet Gynecol Scand 2010, 89:355-359.
22. Emmons S.L., Krohn M., Jackson M., et al. Development of wound infections among women undergoing cesarean section. Obstet Gynecol 1988, 72:559-564.
23. Henderson E., Love E.J. Incidence of hospital-acquired infections associated with caesarean section. JHosp Infect 1995, 29:245-255.
24. Killian C.A., Graffunder E.M., Vinciguerra T.J., et al. Risk factors for surgical-site infections following cesarean section. Infect Control Hosp Epidemiol 2001, 22:613-617.
25. McLean M., Hines R., Polinkovsky M., et al. Type of skin incision and wound complications in the obese parturient. Am J Perinatol 2012, 29:301-306.
26. Pelle H., Jepsen O.B., Larsen S.O., et al. Wound infection after cesarean section. Infect Control 1986, 7:456-461.
27. Takoudes T.C., Weitzen S., Slocum J., et al. Risk of cesarean wound complications in diabetic gestations. Am J Obstet Gynecol 2004, 191:958-963.
28. Janis J.E., Kwon R.K., Lalonde D.H. Apractical guide to wound healing. Plast Reconstr Surg 2010, 125:230e-244e.
29. Stadelmann W.K., Digenis A.G., Tobin G.R. Impediments to wound healing. Am J Surg 1998, 176:39S-47S.
30. Stechmiller J.K. Understanding the role of nutrition and wound healing. Nutr Clin Pract 2010, 25:61-68.
31. Alexander J.M., Leveno K.J., Rouse D.J., et al. National Institute of Child Health and Human Development (NICHD) Maternal-Fetal Medicine Units Network (MFMU). Comparison of maternal and infant outcomes from primary cesarean delivery during the second compared with first stage of labor. Obstet Gynecol 2007, 109:917-921.
32. Spong C.Y., Berghella V., Wenstrom K.D., et al. Preventing the first cesarean delivery: summary of a joint Eunice Kennedy Shriver National Institute of Child Health and Human Development, Society for Maternal-Fetal Medicine, and American College of Obstetricians and Gynecologists Workshop. Obstet Gynecol 2012, 120:1181-1193.
33. Cetin A., Cetin M. Superficial wound disruption after cesarean delivery: effect of the depth and closure of subcutaneous tissue. Int J Gynaecol Obstet 1997, 57:17-21.
34. Chelmow D., Rodriguez E.J., Sabatini M.M. Suture closure of subcutaneous fat and wound disruption after cesarean delivery: a meta-analysis. Obstet Gynecol 2004, 103:974-980.
35. Tipton A.M., Cohen S.A., Chelmow D. Wound infection in the obese pregnant woman. Semin Perinatol 2011, 35:345-349.
36. Gates S., Anderson E.R. Wound drainage for caesarean section. Cochrane Database Syst Rev 2013, (12). CD004549.
37. Hellums E.K., Lin M.G., Ramsey P.S. Prophylactic subcutaneous drainage for prevention of wound complications after cesarean delivery-a metaanalysis. Am J Obstet Gynecol 2007, 197:229-235.
38. Arnold M., Barbul A. Nutrition and wound healing. Plast Reconstr Surg 2006, 117:42S-58S.
39. Wicke C., Halliday B., Allen D., et al. Effects of steroids and retinoids on wound healing. Arch Surg 2000, 135:1265-1270.
40. Munn M.B., Rouse D.J., Owen J. Intraoperative hypothermia and post-cesarean wound infection. Obstet Gynecol 1998, 91(4):582-584.
41. American College of Obstetricians and Gynecologists ACOG practice bulletin No. 120: use of prophylactic antibiotics in labor and delivery. Obstet Gynecol 2011, 117:1472-1483.
42. Tita A.T., Rouse D.J., Blackwell S., et al. Emerging concepts in antibiotic prophylaxis for cesarean delivery: a systematic review. Obstet Gynecol 2009, 113:675-682.
43. Smaill F.M., Gyte G.M. Antibiotic prophylaxis versus no prophylaxis for preventing infection after cesarean section. Cochrane Database Syst Rev 2010, (1). CD007482.
44. Alfirevic Z., Gyte G.M., Dou L. Different classes of antibiotics given to women routinely for preventing infection at caesarean section. Cochrane Database Syst Rev 2010, (10). CD008726.
45. Pevzner L., Swank M., Krepel C., et al. Effects of maternal obesity on tissue concentrations of prophylactic cefazolin during cesarean delivery. Obstet Gynecol 2011, 117:877-882.
46. Dahlke J.D., Mendez-Figueroa H., Rouse D.J., et al. Evidence-based surgery for cesarean delivery: an updated systematic review. Am J Obstet Gynecol 2013, 209:294-306.
47. Hadiati D.R., Hakimi M., Nurdiati D.S. Skin preparation for preventing infection following caesarean section. Cochrane Database Syst Rev 2012, (9). CD007462.
48. Darouiche R.O., Wall M.J., Itani K.M., et al. Chlorhexidine-alcohol versus povidone-iodine for surgical-site antisepsis. NEngl J Med 2010, 362:18-26.
49. Haas D.M., Morgan S., Contreras K. Vaginal preparation with antiseptic solution before cesarean section for preventing postoperative infections. Cochrane Database Syst Rev 2013, (1). CD007892.
50. Duff P. Asimple checklist for preventing major complications associated with cesarean delivery. Obstet Gynecol 2010, 116:1393-1396.
51. Ramsey P.S., White A.M., Guinn D.A., et al. Subcutaneous tissue reapproximation, alone or in combination with drain, in obese women undergoing cesarean delivery. Obstet Gynecol 2005, 105:967-973.
52. Walter C.J., Dumville J.C., Sharp C.A., et al. Systematic review and meta-analysis of wound dressings in the prevention of surgical-site infections in surgical wounds healing by primary intention. Br J Surg 2012, 99:1185-1194.
53. Connery S.A., Downes K.L., Young C. Aretrospective study evaluating silver-impregnated dressings on cesarean wound healing. Adv Skin Wound Care 2012, 25:414-419.
54. Hudson D.A., Adams K.G., Huyssteen A.V., et al. Simplified negative pressure wound therapy: clinical evaluation of an ultraportable, no-canister system. Int Wound J 2013, [Epub ahead of print].
55. Webster J., Scuffham P., Sherriff K.L., et al. Negative pressure wound therapy for skin grafts and surgical wounds healing by primary intention. Cochrane Database Syst Rev 2012, (4). CD009261.
56. Gibbs C., Orth T., Gerkovich M., et al. Traditional dressing compared with an external negative pressure system in preventing wound complications. Obstet Gynecol 2014, 123(Suppl 1):145S.
57. Toon C.D., Ramamoorthy R., Davidson B.R., et al. Early versus delayed dressing removal after primary closure of clean and clean-contaminated surgical wounds. Cochrane Database Syst Rev 2013, (9). CD010259.
58. Toon C.D., Sinha S., Davidson B.R., et al. Early versus delayed post-operative bathing or showering to prevent wound complications. Cochrane Database Syst Rev 2013, (10). CD010075.
59. Wild T., Rahbarnia A., Kellner M., et al. Basics in nutrition and wound healing. Nutrition 2010, 26:862-866.
60. Li J., Chen J., Kirsner R. Pathophysiology of acute wound healing. Clin Dermatol 2007, 25:9-18.
61. Roberts S., Maccato M., Faro S., et al. The microbiology of post-cesarean wound morbidity. Obstet Gynecol 1993, 81:383-386.
62. Andrews W.W., Shah S.R., Goldenberg R.L., et al. Association of post-cesarean delivery endometritis with colonization of the chorioamnion by Ureaplasma urealyticum. Obstet Gynecol 1995, 85:509-514.
63. Owen J., Andrews W.W. Wound complications after cesarean sections. Clin Obstet Gynecol 1994, 37:842-855.
64. Williams obstetrics 2014, McGraw-Hill, New York. 24th edition. F.G. Cunningham, K.J. Leveno, S.L. Bloom (Eds.).
65. Mudge E.J. Recent accomplishments in wound healing. Int Wound J 2014, [Epub ahead of print].
66. Smith F., Dryburgh N., Donaldson J., et al. Debridement for surgical wounds. Cochrane Database Syst Rev 2013, (9). CD006214.
67. McNeeley S.G., Hendrix S.L., Bennett S.M., et al. Synthetic graft placement in the treatment of fascial dehiscence with necrosis and infection. Am J Obstet Gynecol 1998, 179:1430-1434.
68. Goepfert A.R., Guinn D.A., Andrews W.W., et al. Necrotizing fasciitis after cesarean delivery. Obstet Gynecol 1997, 89:409-412.
69. Gallup D.G., Meguiar R.V. Coping with necrotizing fasciitis. Contemp Ob Gyn 2004, 49:38.
70. Vermeulen H., Ubbink D., Goossens A., et al. Dressings and topical agents for surgical wounds healing by secondary intention. Cochrane Database Syst Rev 2004, (2). CD003554.
71. Argenta P.A., Rahaman J., Gretz H.F., et al. Vacuum-assisted closure in the treatment of complex gynecologic wound failures. Obstet Gynecol 2002, 99:497-501.
72. Wechter M.E., Pearlman M.D., Hartmann K.E. Reclosure of the disrupted laparotomy wound: a systematic review. Obstet Gynecol 2005, 106:376-383.