Effects of maternal obesity on tissue concentrations of prophylactic cefazolin during cesarean delivery

Obstetrics and Gynecology

Volumn 117, Issue 4, 2011, Pages 877-882

  Pevzner, Leo ^a,b,c   Swank, Morgan ^a,b,c   Krepel, Candace ^a,b,c   Wing, Deborah A ^a,b,c   Chan, Kenneth ^a,b,c   Edmiston, Charles E ^a,b,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

^c LONG BEACH MEMORIAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CEFAZOLIN;

ADIPOSE TISSUE; ADULT; ANTIBIOTIC PROPHYLAXIS; ARTICLE; BODY MASS; CESAREAN SECTION; CLINICAL ARTICLE; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG TISSUE LEVEL; FEMALE; HUMAN; INFECTION PREVENTION; MATERNAL DISEASE; MINIMUM INHIBITORY CONCENTRATION; OBESITY; PRIORITY JOURNAL; SURGICAL INFECTION;

ADIPOSITY; ADULT; ANTHROPOMETRY; ANTIBIOTIC PROPHYLAXIS; BODY MASS INDEX; CEFAZOLIN; CESAREAN SECTION; FEMALE; FOLLOW-UP STUDIES; HUMANS; OBESITY; OBESITY, MORBID; PREGNANCY; PREOPERATIVE CARE; RISK ASSESSMENT; SURGICAL WOUND INFECTION; TREATMENT OUTCOME; YOUNG ADULT;

EID: 79953173265     PISSN: 00297844     EISSN: None     Source Type: Journal    
DOI: 10.1097/AOG.0b013e31820b95e4     Document Type: Article

References (15)

1. Kirkland KB, Briggs JP, Trivette SL, Wilkinson WE, Sexton DJ. The impact of surgical-site infections in the 1990s: attributable mortality, excess length of hospitalization, and extra cost. Infect Control Hosp Epidemiol 1999;20:725-30.
2. Mangram AJ, Horan TC, Pearson ML, Silver LC, Jarvis WR. Guideline for prevention of surgical site infection, 1999. Centers for Disease Control and Prevention (CDC) Hospital Infection Control Practices Advisory Committee. Am J Infect Control 1999;27:97-132.
3. Barie PS. Surgical site infections: epidemiology and prevention. Surg Infect (Larchmt) 2002;3(suppl 1):S9 -21.
4. Liu P, Derendorf H. Antimicrobial tissue concentrations. Infect Dis Clin North Am 2003;17:599-613. (Pubitemid 38029155)
5. Ogden CL, Carroll MD, Curtin LR, McDowell MA, Tabak CJ, Flegal KM. Prevalence of overweight and obesity in the United States, 1999-2004. JAMA 2006;295:1549-55.
6. Obesity in pregnancy. ACOG Committee Opinion No. 315. American College of Obstetricians and Gynecologists. Obstet Gynecol 2005;106:671-5.
7. Tita AT, Rouse DJ, Blackwell S, Saade GR, Spong CY, Andrews WW. Emerging concepts in antibiotic prophylaxis for cesarean delivery: a systematic review. Obstet Gynecol 2009;113:675-82.
8. World Health Organization. BMI classification. Available at: http://www.who.int/bmi/index.jsp?introPage-intro-3.html. Retrieved August 2, 2010.
9. Edmiston CE, Krepel C, Kelly H, Larson J, Andris D, Hennen C, et al. Perioperative antibiotic prophylaxis in the gastric bypass patient: do we achieve therapeutic levels? Surgery 2004;136:738-47. (Pubitemid 39311298)
10. Forse RA, Karam B, MacLean LD, Christou NV. Antibiotic prophylaxis for surgery in morbidly obese patients. Surgery 1989;106:750-6.
11. Clinical and Laboratory Standards Institute. Performance standards for antimicrobial susceptibility testing: twentieth informational supplement, M100-S20. Vol. 30, No. 1. Wayne (PA): Clinical Laboratory Standards Institute; 2010.
12. Fiore Mitchell T, Pearlman MD, Chapman RL, Bhatt-Mehta V, Faix RG. Maternal and transplacental pharmacokinetics of cefazolin. Obstet Gynecol 2001;98:1075-9. (Pubitemid 34075333)
13. Allegaert K, van Mieghem T, Verbesselt R, de Hoon J, Rayyan M, Devlieger R, et al. Cefazolin pharmacokinetics in maternal plasma and amniotic fluid during pregnancy. Am J Obstet Gynecol 2009;200:170.e1-7.
14. Bratzler DW, Houck PM; Surgical Infection Prevention Guideline Writers Workgroup. Antimicrobial prophylaxis for surgery: an advisory statement from the National Surgical Infection Prevention Project. Am J Surg 2005;189:395-404. (Pubitemid 40488232)
15. Anaya DA, Dellinger EP. The obese surgical patient: a susceptible host for infection. Surg Infect (Larchmt) 2006;7:473-80. (Pubitemid 44857100)