Development of a flow cytometry-based pulse-width assay for detection of aggregates in cellular therapeutics to be infused by catheter

Cytotherapy

Volumn 16, Issue 11, 2014, Pages 1545-1557

  Hickerson, Darren H M ^a   White, Hannah Storrie ^a   Nguyen, Alan ^a   Nieman, Elizabeth ^a   Meadows, Norin ^a   Gentry, Tracy ^b   Foster, Sandra J ^c   Balber, Andrew E ^b   Fiordalisi, Michelle ^a   Hinson, James M ^d  

^a Bank of America   (United States)

^b DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c LLC   (United States)

^d Unicorn Pharma   (United States)

Author keywords

Bone marrow; Cell aggregation; Flow cytometry; Pulse width; Stem cells; Stroke

Indexed keywords

ALDEHYDE DEHYDROGENASE; CONCANAVALIN A; MICROSPHERE;

ARTERY CATHETER; ARTICLE; BRAIN ISCHEMIA; CALIBRATION; CELL AGGREGATION; CELL ASSAY; CELL COUNT; CELL PRODUCT RELEASE ASSAY; CELL SELECTION; CELL THERAPY; CLINICAL TRIAL (TOPIC); CONTROLLED STUDY; FLOW CYTOMETER; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN TISSUE; INTERMETHOD COMPARISON; LIMIT OF DETECTION; NORMAL HUMAN; PARTICLE SIZE; PROTEIN EXPRESSION; PULSE WIDTH FLOW CYTOMETRY; PURIFICATION; QUANTITATIVE ANALYSIS; ADVERSE EFFECTS; BIOLOGICAL THERAPY; BIOSYNTHESIS; BONE MARROW CELL; CATHETER; CEREBROVASCULAR ACCIDENT; GENE EXPRESSION REGULATION; IMMUNOLOGY; ISOLATION AND PURIFICATION; PATHOLOGY; STEM CELL;

ALDEHYDE DEHYDROGENASE; BONE MARROW CELLS; BRAIN ISCHEMIA; CATHETERS; CELL AGGREGATION; CELL- AND TISSUE-BASED THERAPY; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; HUMANS; LIMIT OF DETECTION; STEM CELLS; STROKE;

EID: 84912521458     PISSN: 14653249     EISSN: 14772566     Source Type: Journal    
DOI: 10.1016/j.jcyt.2014.05.004     Document Type: Article

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