Chemical profiling with HPLC-FTMS of exogenous and endogenous chemicals susceptible to the administration of chotosan in an animal model of type 2 diabetes-induced dementia

Journal of Pharmaceutical and Biomedical Analysis

Volumn 104, Issue , 2015, Pages 21-30

  Niu, Yimin ^a   Li, Feng ^a   Inada, Chikako ^a   Tanaka, Ken ^a,c   Watanabe, Shiro ^a   Fujiwara, Hironori ^a   Sasaki Hamada, Sachie ^b   Oka, Jun Ichiro ^b   Matsumoto, Kinzo ^a  

^a UNIVERSITY OF TOYAMA   (Japan)

^b TOKYO UNIVERSITY OF SCIENCE   (Japan)

^c RITSUMEIKAN UNIVERSITY   (Japan)

Author keywords

Chotosan; Glycerophosphocholine; HPLC FTMS; Metabonomics; Type 2 diabetic model

Indexed keywords

ALKALOID; CHOTOSAN; CORYNOXEINE; CYSTEINE; GLYCEROPHOSPHOLIPID; GLYCEROPHOSPHORYLCHOLINE; HIRSUTEINE; KAMPO; METHIONINE; NOOTROPIC AGENT; PURINE; RHYNCHOPHYLLINE; SCOPOLAMINE; TACRINE; TRYPTOPHAN; UNCLASSIFIED DRUG; CHOTO-SAN; HERBACEOUS AGENT; NEUROPROTECTIVE AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEMENTIA; DRUG EFFICACY; EXCITOTOXICITY; FOURIER TRANSFORM MASS SPECTROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIPPOCAMPAL NEURONAL CULTURE; IN VITRO STUDY; LIPID BLOOD LEVEL; LIPID BRAIN LEVEL; MALE; MOUSE; NEUROPHARMACOLOGY; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; SLICE CULTURE; ANIMAL; BRAIN CHEMISTRY; CHEMISTRY; COMPLICATION; DISEASE MODEL; DRUG EFFECTS; HIPPOCAMPUS; MASS SPECTROMETRY; METABOLISM; MUTANT MOUSE STRAIN; PROCEDURES;

ANIMALS; BRAIN CHEMISTRY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DEMENTIA; DIABETES MELLITUS, TYPE 2; DISEASE MODELS, ANIMAL; DRUGS, CHINESE HERBAL; HIPPOCAMPUS; MALE; MASS SPECTROMETRY; MICE, MUTANT STRAINS; NEUROPROTECTIVE AGENTS;

EID: 84912138961     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2014.11.019     Document Type: Article

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