메뉴 건너뛰기




Volumn 20, Issue 12, 2014, Pages 1899-1904

Therapeutic benefit of bortezomib on acute graft-versus-host disease is tissue specific and is associated with interleukin-6 levels

Author keywords

Anti IL 6 therapy; Bortezomib; Skin acute graft versus host disease

Indexed keywords

BORTEZOMIB; INTERLEUKIN 6; ANTINEOPLASTIC AGENT; BORONIC ACID DERIVATIVE; NEUTRALIZING ANTIBODY; PYRAZINE DERIVATIVE;

EID: 84912104023     PISSN: 10838791     EISSN: 15236536     Source Type: Journal    
DOI: 10.1016/j.bbmt.2014.07.022     Document Type: Article
Times cited : (21)

References (33)
  • 1
    • 34247573902 scopus 로고    scopus 로고
    • Graft-versus-host disease
    • Shlomchik W.D. Graft-versus-host disease. Nat Rev Immunol 2007, 7:340-352.
    • (2007) Nat Rev Immunol , vol.7 , pp. 340-352
    • Shlomchik, W.D.1
  • 2
    • 77954687870 scopus 로고    scopus 로고
    • Blockade of interleukin-23 signaling results in targeted protection of the colon and allows for separation of graft-versus-host and graft-versus-leukemia responses
    • Das R., Komorowski R., Hessner M.J., et al. Blockade of interleukin-23 signaling results in targeted protection of the colon and allows for separation of graft-versus-host and graft-versus-leukemia responses. Blood 2010, 115:5249-5258.
    • (2010) Blood , vol.115 , pp. 5249-5258
    • Das, R.1    Komorowski, R.2    Hessner, M.J.3
  • 3
    • 34247867901 scopus 로고    scopus 로고
    • Immunobiology of allogeneic hematopoietic stem cell transplantation
    • Welniak L.A., Blazar B.R., Murphy W.J. Immunobiology of allogeneic hematopoietic stem cell transplantation. Ann Rev Immunol 2007, 25:139-170.
    • (2007) Ann Rev Immunol , vol.25 , pp. 139-170
    • Welniak, L.A.1    Blazar, B.R.2    Murphy, W.J.3
  • 4
    • 80052893511 scopus 로고    scopus 로고
    • Implications of TNF-alpha in the pathogenesis and management of GVHD
    • Levine J.E. Implications of TNF-alpha in the pathogenesis and management of GVHD. Int J Hematol 2011, 93:571-577.
    • (2011) Int J Hematol , vol.93 , pp. 571-577
    • Levine, J.E.1
  • 5
    • 84861576998 scopus 로고    scopus 로고
    • Advances in graft-versus-host disease biology and therapy
    • Blazar B.R., Murphy W.J., Abedi M. Advances in graft-versus-host disease biology and therapy. Nat Rev Immunol 2012, 12:443-458.
    • (2012) Nat Rev Immunol , vol.12 , pp. 443-458
    • Blazar, B.R.1    Murphy, W.J.2    Abedi, M.3
  • 6
    • 77953980528 scopus 로고    scopus 로고
    • IL-6: from its discovery to clinical applications
    • Kishimoto T. IL-6: from its discovery to clinical applications. Int Immunol 2010, 22:347-352.
    • (2010) Int Immunol , vol.22 , pp. 347-352
    • Kishimoto, T.1
  • 7
    • 68249160054 scopus 로고    scopus 로고
    • Blockade of interleukin-6 signaling augments regulatory T-cell reconstitution and attenuates the severity of graft-versus-host disease
    • Chen X., Das R., Komorowski R., et al. Blockade of interleukin-6 signaling augments regulatory T-cell reconstitution and attenuates the severity of graft-versus-host disease. Blood 2009, 114:891-900.
    • (2009) Blood , vol.114 , pp. 891-900
    • Chen, X.1    Das, R.2    Komorowski, R.3
  • 8
    • 78751469023 scopus 로고    scopus 로고
    • Interleukin-6 modulates graft-versus-host responses after experimental allogeneic bone marrow transplantation
    • Tawara I., Koyama M., Liu C., et al. Interleukin-6 modulates graft-versus-host responses after experimental allogeneic bone marrow transplantation. Clin Cancer Res 2011, 17:77-88.
    • (2011) Clin Cancer Res , vol.17 , pp. 77-88
    • Tawara, I.1    Koyama, M.2    Liu, C.3
  • 9
    • 84870516776 scopus 로고    scopus 로고
    • IL-6 blockade attenuates the development of murine sclerodermatous chronic graft-versus-host disease
    • Le Huu D., Matsushita T., Jin G., et al. IL-6 blockade attenuates the development of murine sclerodermatous chronic graft-versus-host disease. JInvest Dermatol 2012, 132:2752-2761.
    • (2012) JInvest Dermatol , vol.132 , pp. 2752-2761
    • Le Huu, D.1    Matsushita, T.2    Jin, G.3
  • 10
    • 78049508308 scopus 로고    scopus 로고
    • Effectiveness and safety of tocilizumab, an anti-interleukin-6 receptor monoclonal antibody, in a patient with refractory GI graft-versus-host disease
    • Gergis U., Arnason J., Yantiss R., et al. Effectiveness and safety of tocilizumab, an anti-interleukin-6 receptor monoclonal antibody, in a patient with refractory GI graft-versus-host disease. JClin Oncol 2010, 28:e602-604.
    • (2010) JClin Oncol , vol.28 , pp. e602-604
    • Gergis, U.1    Arnason, J.2    Yantiss, R.3
  • 11
    • 81255163590 scopus 로고    scopus 로고
    • Tocilizumab for the treatment of steroid refractory graft-versus-host disease
    • Drobyski W.R., Pasquini M., Kovatovic K., et al. Tocilizumab for the treatment of steroid refractory graft-versus-host disease. Biol Blood Marrow Transplant 2011, 17:1862-1868.
    • (2011) Biol Blood Marrow Transplant , vol.17 , pp. 1862-1868
    • Drobyski, W.R.1    Pasquini, M.2    Kovatovic, K.3
  • 12
    • 84864568543 scopus 로고    scopus 로고
    • Proteasome inhibitors in multiple myeloma: 10 years later
    • Moreau P., Richardson P.G., Cavo M., et al. Proteasome inhibitors in multiple myeloma: 10 years later. Blood 2012, 120:947-959.
    • (2012) Blood , vol.120 , pp. 947-959
    • Moreau, P.1    Richardson, P.G.2    Cavo, M.3
  • 13
    • 80051915832 scopus 로고    scopus 로고
    • Anti-inflammatory and immunomodulatory effects of bortezomib in various invivo models
    • Tung D., Cheung P.H., Kaur P., et al. Anti-inflammatory and immunomodulatory effects of bortezomib in various invivo models. Pharmacology 2011, 88:100-113.
    • (2011) Pharmacology , vol.88 , pp. 100-113
    • Tung, D.1    Cheung, P.H.2    Kaur, P.3
  • 14
    • 71849095762 scopus 로고    scopus 로고
    • Proteasome inhibition up-regulates inflammatory gene transcription induced by an atypical pathway of NF-kappaB activation
    • Cullen S.J., Ponnappan S., Ponnappan U. Proteasome inhibition up-regulates inflammatory gene transcription induced by an atypical pathway of NF-kappaB activation. Biochem Pharmacol 2010, 79:706-714.
    • (2010) Biochem Pharmacol , vol.79 , pp. 706-714
    • Cullen, S.J.1    Ponnappan, S.2    Ponnappan, U.3
  • 15
    • 67650767034 scopus 로고    scopus 로고
    • Treatment with bortezomib of human CD4+ T cells preserves natural regulatory T cells and allows the emergence of a distinct suppressor T-cell population
    • Blanco B., Perez-Simon J.A., Sanchez-Abarca L.I., et al. Treatment with bortezomib of human CD4+ T cells preserves natural regulatory T cells and allows the emergence of a distinct suppressor T-cell population. Haematologica 2009, 94:975-983.
    • (2009) Haematologica , vol.94 , pp. 975-983
    • Blanco, B.1    Perez-Simon, J.A.2    Sanchez-Abarca, L.I.3
  • 16
    • 59249101291 scopus 로고    scopus 로고
    • Sensitization of human breast cancer cells to natural killer cell-mediated cytotoxicity by proteasome inhibition
    • Ames E., Hallett W.H., Murphy W.J. Sensitization of human breast cancer cells to natural killer cell-mediated cytotoxicity by proteasome inhibition. Clin Exp Immunol 2009, 155:504-513.
    • (2009) Clin Exp Immunol , vol.155 , pp. 504-513
    • Ames, E.1    Hallett, W.H.2    Murphy, W.J.3
  • 17
    • 84866546465 scopus 로고    scopus 로고
    • Bortezomib-based graft-versus-host disease prophylaxis in HLA-mismatched unrelated donor transplantation
    • Koreth J., Stevenson K.E., Kim H.T., et al. Bortezomib-based graft-versus-host disease prophylaxis in HLA-mismatched unrelated donor transplantation. JClin Oncol 2012, 30:3202-3208.
    • (2012) JClin Oncol , vol.30 , pp. 3202-3208
    • Koreth, J.1    Stevenson, K.E.2    Kim, H.T.3
  • 18
    • 70449723162 scopus 로고    scopus 로고
    • Bortezomib, tacrolimus, and methotrexate for prophylaxis of graft-versus-host disease after reduced-intensity conditioning allogeneic stem cell transplantation from HLA-mismatched unrelated donors
    • Koreth J., Stevenson K.E., Kim H.T., et al. Bortezomib, tacrolimus, and methotrexate for prophylaxis of graft-versus-host disease after reduced-intensity conditioning allogeneic stem cell transplantation from HLA-mismatched unrelated donors. Blood 2009, 114:3956-3959.
    • (2009) Blood , vol.114 , pp. 3956-3959
    • Koreth, J.1    Stevenson, K.E.2    Kim, H.T.3
  • 19
    • 27644477944 scopus 로고    scopus 로고
    • Differential effects of proteasome inhibition by bortezomib on murine acute graft-versus-host disease (GVHD): delayed administration of bortezomib results in increased GVHD-dependent gastrointestinal toxicity
    • Sun K., Wilkins D.E., Anver M.R., et al. Differential effects of proteasome inhibition by bortezomib on murine acute graft-versus-host disease (GVHD): delayed administration of bortezomib results in increased GVHD-dependent gastrointestinal toxicity. Blood 2005, 106:3293-3299.
    • (2005) Blood , vol.106 , pp. 3293-3299
    • Sun, K.1    Wilkins, D.E.2    Anver, M.R.3
  • 20
    • 84864817966 scopus 로고    scopus 로고
    • IFN-gamma receptor-deficient donor T cells mediate protection from graft-versus-host disease and preserve graft-versus-tumor responses after allogeneic bone marrow transplantation
    • Sun K., Hsiao H.H., Li M., et al. IFN-gamma receptor-deficient donor T cells mediate protection from graft-versus-host disease and preserve graft-versus-tumor responses after allogeneic bone marrow transplantation. JImmunol 2012, 189:2033-2042.
    • (2012) JImmunol , vol.189 , pp. 2033-2042
    • Sun, K.1    Hsiao, H.H.2    Li, M.3
  • 21
    • 4444354779 scopus 로고    scopus 로고
    • Recipient CD4+ T cells that survive irradiation regulate chronic graft-versus-host disease
    • Anderson B.E., McNiff J.M., Matte C., et al. Recipient CD4+ T cells that survive irradiation regulate chronic graft-versus-host disease. Blood 2004, 104:1565-1573.
    • (2004) Blood , vol.104 , pp. 1565-1573
    • Anderson, B.E.1    McNiff, J.M.2    Matte, C.3
  • 22
    • 37549030450 scopus 로고    scopus 로고
    • Blood-derived dermal langerin+ dendritic cells survey the skin in the steady state
    • Ginhoux F., Collin M.P., Bogunovic M., et al. Blood-derived dermal langerin+ dendritic cells survey the skin in the steady state. JExp Med 2007, 204:3133-3146.
    • (2007) JExp Med , vol.204 , pp. 3133-3146
    • Ginhoux, F.1    Collin, M.P.2    Bogunovic, M.3
  • 23
    • 0033575383 scopus 로고    scopus 로고
    • Prevention of graft versus host disease by inactivation of host antigen-presenting cells
    • Shlomchik W.D., Couzens M.S., Tang C.B., et al. Prevention of graft versus host disease by inactivation of host antigen-presenting cells. Science 1999, 285:412-415.
    • (1999) Science , vol.285 , pp. 412-415
    • Shlomchik, W.D.1    Couzens, M.S.2    Tang, C.B.3
  • 24
    • 24744435772 scopus 로고    scopus 로고
    • Directing transition from innate to acquired immunity: defining a role for IL-6
    • Jones S.A. Directing transition from innate to acquired immunity: defining a role for IL-6. JImmunol 2005, 175:3463-3468.
    • (2005) JImmunol , vol.175 , pp. 3463-3468
    • Jones, S.A.1
  • 25
    • 22144492213 scopus 로고    scopus 로고
    • IL-6 trans-signaling via STAT3 directs T cell infiltration in acute inflammation
    • McLoughlin R.M., Jenkins B.J., Grail D., et al. IL-6 trans-signaling via STAT3 directs T cell infiltration in acute inflammation. Proc Natl Acad Sci U S A 2005, 102:9589-9594.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 9589-9594
    • McLoughlin, R.M.1    Jenkins, B.J.2    Grail, D.3
  • 26
    • 2542599273 scopus 로고    scopus 로고
    • Inhibition of acute graft-versus-host disease with retention of graft-versus-tumor effects by the proteasome inhibitor bortezomib
    • Sun K., Welniak L.A., Panoskaltsis-Mortari A., et al. Inhibition of acute graft-versus-host disease with retention of graft-versus-tumor effects by the proteasome inhibitor bortezomib. Proc Natl Acad Sci U S A 2004, 101:8120-8125.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 8120-8125
    • Sun, K.1    Welniak, L.A.2    Panoskaltsis-Mortari, A.3
  • 27
    • 51649122311 scopus 로고    scopus 로고
    • Differential effects of donor T-cell cytokines on outcome with continuous bortezomib administration after allogeneic bone marrow transplantation
    • Sun K., Li M., Sayers T.J., et al. Differential effects of donor T-cell cytokines on outcome with continuous bortezomib administration after allogeneic bone marrow transplantation. Blood 2008, 112:1522-1529.
    • (2008) Blood , vol.112 , pp. 1522-1529
    • Sun, K.1    Li, M.2    Sayers, T.J.3
  • 28
    • 84900551607 scopus 로고    scopus 로고
    • Dexamethasone Palmitate Ameliorates Macrophages-Rich Graft-versus-Host Disease by Inhibiting Macrophage Functions
    • Nishiwaki S., Nakayama T., Murata M., et al. Dexamethasone Palmitate Ameliorates Macrophages-Rich Graft-versus-Host Disease by Inhibiting Macrophage Functions. PloS One 2014, 9:e96252.
    • (2014) PloS One , vol.9 , pp. e96252
    • Nishiwaki, S.1    Nakayama, T.2    Murata, M.3
  • 29
    • 84892476632 scopus 로고    scopus 로고
    • Interleukin-6 signaling drives fibrosis in unresolved inflammation
    • Fielding C.A., Jones G.W., McLoughlin R.M., et al. Interleukin-6 signaling drives fibrosis in unresolved inflammation. Immunity 2014, 40:40-50.
    • (2014) Immunity , vol.40 , pp. 40-50
    • Fielding, C.A.1    Jones, G.W.2    McLoughlin, R.M.3
  • 30
    • 0034960582 scopus 로고    scopus 로고
    • Il-6 and its soluble receptor orchestrate a temporal switch in the pattern of leukocyte recruitment seen during acute inflammation
    • Hurst S.M., Wilkinson T.S., McLoughlin R.M., et al. Il-6 and its soluble receptor orchestrate a temporal switch in the pattern of leukocyte recruitment seen during acute inflammation. Immunity 2001, 14:705-714.
    • (2001) Immunity , vol.14 , pp. 705-714
    • Hurst, S.M.1    Wilkinson, T.S.2    McLoughlin, R.M.3
  • 31
    • 37049011238 scopus 로고    scopus 로고
    • CXCL10-CXCR3 interactions play an important role in the pathogenesis of acute graft-versus-host disease in the skin following allogeneic stem-cell transplantation
    • Piper K.P., Horlock C., Curnow S.J., et al. CXCL10-CXCR3 interactions play an important role in the pathogenesis of acute graft-versus-host disease in the skin following allogeneic stem-cell transplantation. Blood 2007, 110:3827-3832.
    • (2007) Blood , vol.110 , pp. 3827-3832
    • Piper, K.P.1    Horlock, C.2    Curnow, S.J.3
  • 32
    • 27644442438 scopus 로고    scopus 로고
    • CCR2 is required for CD8-induced graft-versus-host disease
    • Terwey T.H., Kim T.D., Kochman A.A., et al. CCR2 is required for CD8-induced graft-versus-host disease. Blood 2005, 106:3322-3330.
    • (2005) Blood , vol.106 , pp. 3322-3330
    • Terwey, T.H.1    Kim, T.D.2    Kochman, A.A.3
  • 33
    • 0038494591 scopus 로고    scopus 로고
    • Early changes in gene expression profiles of hepatic GVHD uncovered by oligonucleotide microarrays
    • Ichiba T., Teshima T., Kuick R., et al. Early changes in gene expression profiles of hepatic GVHD uncovered by oligonucleotide microarrays. Blood 2003, 102:763-771.
    • (2003) Blood , vol.102 , pp. 763-771
    • Ichiba, T.1    Teshima, T.2    Kuick, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.