Preparation and in vitro characterization of thermosensitive and mucoadhesive hydrogels for nasal delivery of phenylephrine hydrochloride

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 88, Issue 3, 2014, Pages 998-1004

  Xu, Xiaofeng ^a,c   Shen, Yan ^a   Wang, Wei ^b   Sun, Chunmeng ^a   Li, Chang ^a   Xiong, Yerong ^a   Tu, Jiasheng ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b JOHNSON AND JOHNSON   (United States)

^c Bayi Hospital and Chairman of PLA   (China)

Author keywords

e polylysine; Mucoadhesive; Nasal spray; Phenylephrine hydrochloride; Poloxamer; Sodium hyaluronate; Thermosensitive hydrogel

Indexed keywords

HYALURONIC ACID; NOSE SPRAY; PHENYLEPHRINE; POLOXAMER; POLYLYSINE; SODIUM CHLORIDE; ADHESIVE AGENT; HYDROGEL;

ADHESION; ARTICLE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG RELEASE; EUKARYOTIC FLAGELLUM; FLOW KINETICS; GELATION; HEAT SENSITIVITY; HYDROGEL; IN VITRO STUDY; MOLECULAR WEIGHT; MUCOADHESION; NOSE CAVITY; NOSE OBSTRUCTION; SHEAR STRESS; SUSTAINED DRUG RELEASE; TEMPERATURE; ADMINISTRATION AND DOSAGE; ANIMAL; ANURA; DRUG EFFECTS; INTRANASAL DRUG ADMINISTRATION; METABOLISM; MUCOSA; PIG; PROCEDURES; SYNTHESIS;

ADHESIVES; ADMINISTRATION, INTRANASAL; ANIMALS; ANURA; DRUG DELIVERY SYSTEMS; HYDROGELS; MUCOUS MEMBRANE; PHENYLEPHRINE; SWINE; TEMPERATURE;

EID: 84912085193     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2014.08.015     Document Type: Article

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